Zinc in PDB 8c4d: N-Acetylmuramoyl-L-Alanine Amidase From Enterococcus Faecium Prophage Genome

The structure of N-Acetylmuramoyl-L-Alanine Amidase From Enterococcus Faecium Prophage Genome, PDB code: 8c4d was solved by A.C.Papageorgiou, G.E.Premetis, N.E.Labrou, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.73 / 1.97
Space group	P 43 2 2
Cell size a, b, c (Å), α, β, γ (°)	74.713, 74.713, 133.272, 90, 90, 90
R / Rfree (%)	17.3 / 19.5

The structure of N-Acetylmuramoyl-L-Alanine Amidase From Enterococcus Faecium Prophage Genome also contains other interesting chemical elements:

Sodium	(Na)	3 atoms
Chlorine	(Cl)	4 atoms

The binding sites of Zinc atom in the N-Acetylmuramoyl-L-Alanine Amidase From Enterococcus Faecium Prophage Genome (pdb code 8c4d). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the N-Acetylmuramoyl-L-Alanine Amidase From Enterococcus Faecium Prophage Genome, PDB code: 8c4d:

Zinc binding site 1 out of 1 in the N-Acetylmuramoyl-L-Alanine Amidase From Enterococcus Faecium Prophage Genome


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of N-Acetylmuramoyl-L-Alanine Amidase From Enterococcus Faecium Prophage Genome within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn402 b:37.8 occ:1.00 ND1 A:HIS27 2.2 24.6 1.0 ND1 A:HIS132 2.2 32.6 1.0 SG A:CYS140 2.3 30.6 1.0 CL A:CL403 2.8 60.4 1.0 O A:HOH655 3.1 55.7 1.0 CG A:HIS132 3.1 28.6 1.0 CG A:HIS27 3.2 23.9 1.0 CB A:CYS140 3.2 40.4 1.0 CE1 A:HIS27 3.2 25.8 1.0 CE1 A:HIS132 3.3 33.8 1.0 CB A:HIS132 3.3 26.6 1.0 CB A:HIS27 3.4 25.2 1.0 CA A:HIS27 4.1 24.6 1.0 CD2 A:HIS132 4.3 31.8 1.0 CD2 A:HIS27 4.3 25.9 1.0 NE2 A:HIS27 4.3 24.4 1.0 NE2 A:HIS132 4.4 37.7 1.0 O A:HOH504 4.4 28.2 1.0 OE1 A:GLU90 4.4 37.2 1.0 O A:HOH599 4.6 60.1 1.0 O A:HIS76 4.7 26.3 1.0 CA A:CYS140 4.7 33.4 1.0 O A:ASN28 4.7 26.8 1.0 N A:ASN28 4.8 23.3 1.0 CA A:HIS132 4.8 26.0 1.0 O A:HOH629 4.9 58.5 1.0

G.E.Premetis, A.Stathi, A.C.Papageorgiou, N.E.Labrou. Structural and Functional Features of A Broad-Spectrum Prophage-Encoded Enzybiotic From Enterococcus Faecium. Sci Rep V. 13 7450 2023.
ISSN: ESSN 2045-2322
PubMed: 37156923
DOI: 10.1038/S41598-023-34309-2