Zinc in PDB 9ja1: The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae
Enzymatic activity of The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae
All present enzymatic activity of The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae:
2.7.7.6;
Other elements in 9ja1:
The structure of The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae
(pdb code 9ja1). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the
The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae, PDB code: 9ja1:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
Zinc binding site 1 out
of 6 in 9ja1
Go back to
Zinc Binding Sites List in 9ja1
Zinc binding site 1 out
of 6 in the The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn1801
b:167.4
occ:1.00
|
SG
|
A:CYS110
|
2.3
|
115.9
|
1.0
|
SG
|
A:CYS107
|
2.3
|
113.9
|
1.0
|
SG
|
A:CYS167
|
2.3
|
138.7
|
1.0
|
SG
|
A:CYS148
|
3.2
|
126.8
|
1.0
|
CB
|
A:CYS107
|
3.3
|
103.0
|
1.0
|
CB
|
A:CYS167
|
3.5
|
134.5
|
1.0
|
CB
|
A:CYS110
|
3.6
|
107.9
|
1.0
|
N
|
A:CYS167
|
3.8
|
136.5
|
1.0
|
CB
|
A:CYS148
|
3.8
|
127.7
|
1.0
|
N
|
A:CYS110
|
3.9
|
109.1
|
1.0
|
CA
|
A:CYS167
|
4.2
|
136.2
|
1.0
|
CB
|
A:HIS109
|
4.3
|
110.6
|
1.0
|
CA
|
A:CYS110
|
4.4
|
109.1
|
1.0
|
C
|
A:GLY166
|
4.5
|
131.2
|
1.0
|
CA
|
A:GLY166
|
4.6
|
129.6
|
1.0
|
C
|
A:HIS109
|
4.7
|
107.2
|
1.0
|
CA
|
A:CYS107
|
4.7
|
101.7
|
1.0
|
N
|
A:HIS109
|
4.8
|
104.9
|
1.0
|
CA
|
A:HIS109
|
4.9
|
108.1
|
1.0
|
NE2
|
A:GLN171
|
5.0
|
111.8
|
1.0
|
N
|
A:GLY168
|
5.0
|
127.8
|
1.0
|
|
Zinc binding site 2 out
of 6 in 9ja1
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Zinc Binding Sites List in 9ja1
Zinc binding site 2 out
of 6 in the The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn1802
b:113.4
occ:1.00
|
NE2
|
A:HIS80
|
2.1
|
80.2
|
1.0
|
SG
|
A:CYS77
|
2.3
|
90.6
|
1.0
|
SG
|
A:CYS67
|
2.3
|
92.9
|
1.0
|
SG
|
A:CYS70
|
2.3
|
96.2
|
1.0
|
CD2
|
A:HIS80
|
2.4
|
73.5
|
1.0
|
CE1
|
A:HIS80
|
3.3
|
74.8
|
1.0
|
CB
|
A:CYS67
|
3.4
|
91.3
|
1.0
|
CB
|
A:CYS70
|
3.4
|
87.1
|
1.0
|
CB
|
A:CYS77
|
3.6
|
79.3
|
1.0
|
N
|
A:CYS70
|
3.7
|
90.9
|
1.0
|
CG
|
A:HIS80
|
3.7
|
69.1
|
1.0
|
ND1
|
A:HIS80
|
4.1
|
71.7
|
1.0
|
CA
|
A:CYS70
|
4.2
|
88.4
|
1.0
|
CA
|
A:CYS77
|
4.5
|
76.2
|
1.0
|
O
|
A:LEU58
|
4.5
|
79.5
|
1.0
|
CB
|
A:THR69
|
4.5
|
77.9
|
1.0
|
N
|
A:GLY79
|
4.5
|
63.9
|
1.0
|
CA
|
A:GLY59
|
4.6
|
82.8
|
1.0
|
CA
|
A:GLY79
|
4.7
|
62.7
|
1.0
|
C
|
A:THR69
|
4.8
|
84.1
|
1.0
|
CA
|
A:CYS67
|
4.8
|
89.6
|
1.0
|
CD
|
A:PRO78
|
4.9
|
67.2
|
1.0
|
N
|
A:HIS80
|
4.9
|
69.3
|
1.0
|
C
|
A:GLY79
|
5.0
|
72.8
|
1.0
|
CB
|
A:HIS80
|
5.0
|
67.6
|
1.0
|
C
|
A:CYS77
|
5.0
|
77.5
|
1.0
|
|
Zinc binding site 3 out
of 6 in 9ja1
Go back to
Zinc Binding Sites List in 9ja1
Zinc binding site 3 out
of 6 in the The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn1301
b:141.3
occ:1.00
|
SG
|
B:CYS1163
|
2.3
|
85.8
|
1.0
|
SG
|
B:CYS1182
|
2.3
|
98.2
|
1.0
|
SG
|
B:CYS1185
|
2.3
|
100.3
|
1.0
|
SG
|
B:CYS1166
|
2.3
|
72.8
|
1.0
|
CB
|
B:CYS1163
|
2.9
|
70.3
|
1.0
|
CB
|
B:CYS1182
|
3.4
|
90.3
|
1.0
|
CB
|
B:CYS1166
|
3.7
|
67.7
|
1.0
|
CB
|
B:CYS1185
|
4.0
|
91.5
|
1.0
|
N
|
B:CYS1166
|
4.0
|
68.3
|
1.0
|
CB
|
B:ASN1187
|
4.3
|
84.6
|
1.0
|
CA
|
B:CYS1163
|
4.4
|
69.4
|
1.0
|
CA
|
B:CYS1166
|
4.5
|
65.2
|
1.0
|
O
|
B:CYS1182
|
4.6
|
89.0
|
1.0
|
ND2
|
B:ASN1187
|
4.6
|
91.1
|
1.0
|
CA
|
B:CYS1182
|
4.7
|
88.6
|
1.0
|
C
|
B:CYS1182
|
4.9
|
88.1
|
1.0
|
CB
|
B:ILE1165
|
5.0
|
65.0
|
1.0
|
N
|
B:CYS1185
|
5.0
|
89.8
|
1.0
|
|
Zinc binding site 4 out
of 6 in 9ja1
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Zinc Binding Sites List in 9ja1
Zinc binding site 4 out
of 6 in the The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn401
b:185.1
occ:1.00
|
CB
|
C:CYS88
|
2.1
|
139.3
|
1.0
|
SG
|
C:CYS95
|
2.3
|
95.4
|
1.0
|
SG
|
C:CYS86
|
2.3
|
124.9
|
1.0
|
SG
|
C:CYS88
|
2.3
|
145.2
|
1.0
|
CB
|
C:CYS92
|
3.2
|
89.5
|
1.0
|
CB
|
C:CYS86
|
3.2
|
118.2
|
1.0
|
CB
|
C:CYS95
|
3.3
|
85.0
|
1.0
|
CA
|
C:CYS88
|
3.6
|
138.1
|
1.0
|
SG
|
C:CYS92
|
3.7
|
90.6
|
1.0
|
N
|
C:CYS88
|
4.1
|
139.8
|
1.0
|
O
|
C:GLU89
|
4.2
|
134.5
|
1.0
|
N
|
C:GLU89
|
4.3
|
136.4
|
1.0
|
C
|
C:CYS88
|
4.3
|
140.2
|
1.0
|
CA
|
C:CYS86
|
4.4
|
119.7
|
1.0
|
C
|
C:CYS86
|
4.4
|
121.5
|
1.0
|
O
|
C:CYS86
|
4.5
|
117.7
|
1.0
|
CA
|
C:CYS95
|
4.5
|
84.5
|
1.0
|
CA
|
C:CYS92
|
4.6
|
93.2
|
1.0
|
N
|
C:CYS95
|
4.6
|
80.6
|
1.0
|
C
|
C:PHE87
|
4.8
|
138.2
|
1.0
|
N
|
C:CYS92
|
4.9
|
95.2
|
1.0
|
N
|
C:PHE87
|
5.0
|
138.0
|
1.0
|
|
Zinc binding site 5 out
of 6 in 9ja1
Go back to
Zinc Binding Sites List in 9ja1
Zinc binding site 5 out
of 6 in the The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
J:Zn101
b:103.4
occ:1.00
|
SG
|
J:CYS46
|
2.3
|
66.4
|
1.0
|
SG
|
J:CYS45
|
2.3
|
78.7
|
1.0
|
SG
|
J:CYS7
|
2.3
|
67.9
|
1.0
|
SG
|
J:CYS10
|
2.3
|
59.6
|
1.0
|
N
|
J:CYS46
|
3.2
|
40.5
|
1.0
|
CB
|
J:CYS7
|
3.3
|
45.9
|
1.0
|
CB
|
J:CYS46
|
3.5
|
41.2
|
1.0
|
CA
|
J:CYS46
|
3.5
|
41.3
|
1.0
|
CB
|
J:CYS10
|
3.5
|
48.0
|
1.0
|
C
|
J:CYS45
|
3.6
|
49.1
|
1.0
|
CB
|
J:CYS45
|
3.7
|
55.4
|
1.0
|
N
|
J:CYS10
|
4.0
|
50.2
|
1.0
|
O
|
J:CYS45
|
4.1
|
59.5
|
1.0
|
CA
|
J:CYS45
|
4.3
|
50.0
|
1.0
|
CA
|
J:CYS10
|
4.3
|
45.6
|
1.0
|
CB
|
J:SER9
|
4.6
|
54.3
|
1.0
|
N
|
J:GLY11
|
4.7
|
38.3
|
1.0
|
CA
|
J:CYS7
|
4.7
|
40.1
|
1.0
|
CB
|
J:LYS12
|
4.7
|
44.5
|
1.0
|
C
|
J:SER9
|
4.9
|
56.1
|
1.0
|
N
|
J:LYS12
|
4.9
|
50.8
|
1.0
|
C
|
J:CYS46
|
5.0
|
52.4
|
1.0
|
|
Zinc binding site 6 out
of 6 in 9ja1
Go back to
Zinc Binding Sites List in 9ja1
Zinc binding site 6 out
of 6 in the The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
L:Zn101
b:190.2
occ:1.00
|
SG
|
L:CYS51
|
2.3
|
155.2
|
1.0
|
SG
|
L:CYS48
|
2.3
|
158.8
|
1.0
|
SG
|
L:CYS31
|
2.3
|
145.4
|
1.0
|
SG
|
L:CYS34
|
2.3
|
156.9
|
1.0
|
O
|
L:GLU33
|
2.5
|
147.6
|
1.0
|
CB
|
L:CYS48
|
3.4
|
155.3
|
1.0
|
CB
|
L:CYS31
|
3.4
|
139.3
|
1.0
|
CB
|
L:CYS34
|
3.4
|
153.7
|
1.0
|
CB
|
L:CYS51
|
3.6
|
152.7
|
1.0
|
C
|
L:GLU33
|
3.7
|
146.6
|
1.0
|
N
|
L:CYS51
|
3.7
|
152.4
|
1.0
|
O
|
L:CYS34
|
4.1
|
147.9
|
1.0
|
CA
|
L:CYS51
|
4.1
|
153.0
|
1.0
|
O
|
L:CYS51
|
4.2
|
152.3
|
1.0
|
CA
|
L:CYS34
|
4.2
|
153.3
|
1.0
|
C
|
L:CYS34
|
4.3
|
151.1
|
1.0
|
N
|
L:CYS34
|
4.4
|
152.5
|
1.0
|
C
|
L:CYS51
|
4.6
|
152.2
|
1.0
|
CB
|
L:ASP50
|
4.6
|
151.7
|
1.0
|
CA
|
L:CYS31
|
4.8
|
138.9
|
1.0
|
CA
|
L:CYS48
|
4.8
|
156.5
|
1.0
|
CA
|
L:GLU33
|
4.8
|
145.5
|
1.0
|
C
|
L:ASP50
|
4.8
|
151.4
|
1.0
|
N
|
L:ASP50
|
4.8
|
153.2
|
1.0
|
N
|
L:SER35
|
5.0
|
149.5
|
1.0
|
N
|
L:GLU33
|
5.0
|
145.8
|
1.0
|
|
Reference:
J.Ma,
G.Yi,
P.Zhang.
The Rna Polymerase II Elongation Complex From Saccharomyces Cerevisiae To Be Published.
Page generated: Thu Oct 31 15:41:43 2024
|