Zinc in PDB 9fgp: Cilia and Flagella Associated Protein 299
Protein crystallography data
The structure of Cilia and Flagella Associated Protein 299, PDB code: 9fgp
was solved by
N.D.Wright,
L.Koekemoer,
Structural Genomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
58.07 /
1.49
|
Space group
|
P 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
31.756,
34.449,
58.984,
91.35,
100,
90.09
|
R / Rfree (%)
|
17.5 /
21.9
|
Zinc Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
12;
Binding sites:
The binding sites of Zinc atom in the Cilia and Flagella Associated Protein 299
(pdb code 9fgp). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 12 binding sites of Zinc where determined in the
Cilia and Flagella Associated Protein 299, PDB code: 9fgp:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Zinc binding site 1 out
of 12 in 9fgp
Go back to
Zinc Binding Sites List in 9fgp
Zinc binding site 1 out
of 12 in the Cilia and Flagella Associated Protein 299
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Cilia and Flagella Associated Protein 299 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn301
b:8.3
occ:1.00
|
OD1
|
A:ASP164
|
1.9
|
9.7
|
1.0
|
OE1
|
A:GLU125
|
2.0
|
9.0
|
1.0
|
CG
|
A:ASP164
|
2.8
|
8.6
|
1.0
|
CD
|
A:GLU125
|
2.8
|
9.2
|
1.0
|
OD2
|
A:ASP164
|
3.0
|
9.3
|
1.0
|
OE2
|
A:GLU125
|
3.1
|
11.6
|
1.0
|
O
|
A:HOH433
|
3.7
|
7.0
|
1.0
|
O
|
A:HOH420
|
3.7
|
15.1
|
1.0
|
CB
|
A:ASP164
|
4.2
|
8.8
|
1.0
|
CG
|
A:GLU125
|
4.3
|
8.4
|
1.0
|
N
|
A:ASP164
|
4.6
|
8.0
|
1.0
|
CA
|
A:ASP164
|
4.7
|
7.9
|
1.0
|
CB
|
A:GLU125
|
4.7
|
7.9
|
1.0
|
N
|
A:GLU125
|
4.8
|
7.4
|
1.0
|
|
Zinc binding site 2 out
of 12 in 9fgp
Go back to
Zinc Binding Sites List in 9fgp
Zinc binding site 2 out
of 12 in the Cilia and Flagella Associated Protein 299
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Cilia and Flagella Associated Protein 299 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn302
b:36.5
occ:0.60
|
OE2
|
A:GLU102
|
2.2
|
22.4
|
1.0
|
CD
|
A:GLU102
|
3.0
|
17.7
|
1.0
|
OE1
|
A:GLU102
|
3.1
|
19.1
|
1.0
|
OG
|
B:SER90
|
3.4
|
56.5
|
1.0
|
NH2
|
A:ARG106
|
3.7
|
21.5
|
1.0
|
O
|
B:MET91
|
4.1
|
20.2
|
1.0
|
N
|
B:MET91
|
4.3
|
31.8
|
1.0
|
CG
|
A:GLU102
|
4.4
|
12.1
|
1.0
|
CE2
|
A:PHE145
|
4.5
|
16.8
|
1.0
|
CZ
|
A:ARG106
|
4.7
|
18.1
|
1.0
|
O
|
A:HOH510
|
4.7
|
29.8
|
1.0
|
CB
|
B:SER90
|
4.7
|
45.7
|
1.0
|
NE
|
A:ARG106
|
4.8
|
19.1
|
1.0
|
CD2
|
A:PHE145
|
4.8
|
16.4
|
1.0
|
C
|
B:MET91
|
5.0
|
20.2
|
1.0
|
O
|
A:HOH415
|
5.0
|
16.7
|
1.0
|
|
Zinc binding site 3 out
of 12 in 9fgp
Go back to
Zinc Binding Sites List in 9fgp
Zinc binding site 3 out
of 12 in the Cilia and Flagella Associated Protein 299
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Cilia and Flagella Associated Protein 299 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn303
b:23.8
occ:1.00
|
NH2
|
A:ARG154
|
3.1
|
10.7
|
1.0
|
NZ
|
A:LYS149
|
3.2
|
9.1
|
1.0
|
O
|
A:HOH504
|
3.3
|
17.3
|
1.0
|
O
|
A:HOH518
|
3.5
|
26.5
|
1.0
|
CD
|
A:LYS149
|
3.7
|
8.8
|
1.0
|
CE
|
A:LYS149
|
3.7
|
8.7
|
1.0
|
O
|
A:HOH425
|
3.9
|
8.3
|
1.0
|
NE
|
A:ARG154
|
4.0
|
13.1
|
1.0
|
CZ
|
A:ARG154
|
4.0
|
12.7
|
1.0
|
OH
|
A:TYR144
|
4.1
|
7.6
|
1.0
|
CG
|
A:LYS149
|
4.7
|
8.0
|
1.0
|
OE1
|
A:GLU139
|
5.0
|
14.4
|
1.0
|
|
Zinc binding site 4 out
of 12 in 9fgp
Go back to
Zinc Binding Sites List in 9fgp
Zinc binding site 4 out
of 12 in the Cilia and Flagella Associated Protein 299
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Cilia and Flagella Associated Protein 299 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn304
b:12.4
occ:0.33
|
CD2
|
A:HIS134
|
2.1
|
11.5
|
1.0
|
O
|
A:HOH511
|
2.6
|
9.8
|
1.0
|
NE2
|
A:HIS134
|
3.0
|
12.8
|
1.0
|
CG
|
A:HIS134
|
3.1
|
10.9
|
1.0
|
CD
|
A:LYS137
|
3.1
|
28.8
|
1.0
|
ZN
|
A:ZN306
|
3.5
|
8.5
|
0.5
|
CB
|
A:HIS134
|
3.7
|
11.0
|
1.0
|
NZ
|
A:LYS137
|
3.8
|
34.7
|
1.0
|
CG
|
A:PRO174
|
3.9
|
9.0
|
1.0
|
CA
|
A:HIS134
|
3.9
|
9.3
|
1.0
|
CB
|
A:PRO174
|
4.0
|
9.6
|
1.0
|
CE
|
A:LYS137
|
4.0
|
32.7
|
1.0
|
CE1
|
A:HIS134
|
4.1
|
13.6
|
1.0
|
ND1
|
A:HIS134
|
4.1
|
12.7
|
1.0
|
CG
|
A:LYS137
|
4.2
|
26.8
|
1.0
|
CB
|
A:LYS137
|
4.2
|
21.3
|
1.0
|
O
|
A:HIS134
|
4.5
|
11.6
|
1.0
|
C
|
A:HIS134
|
4.7
|
9.4
|
1.0
|
CG2
|
A:THR138
|
4.9
|
21.3
|
1.0
|
CD
|
A:PRO174
|
4.9
|
9.3
|
1.0
|
N
|
A:HIS134
|
5.0
|
8.7
|
1.0
|
|
Zinc binding site 5 out
of 12 in 9fgp
Go back to
Zinc Binding Sites List in 9fgp
Zinc binding site 5 out
of 12 in the Cilia and Flagella Associated Protein 299
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Cilia and Flagella Associated Protein 299 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn305
b:8.2
occ:1.00
|
OD2
|
A:ASP200
|
2.0
|
10.8
|
1.0
|
CG
|
A:ASP200
|
2.6
|
10.1
|
1.0
|
OD1
|
A:ASP200
|
2.7
|
9.4
|
1.0
|
O
|
A:HOH402
|
3.6
|
10.1
|
1.0
|
CB
|
A:ASP200
|
4.1
|
9.6
|
1.0
|
CD
|
A:PRO201
|
4.6
|
10.7
|
1.0
|
CG
|
A:PRO201
|
4.8
|
11.2
|
1.0
|
CB
|
A:LYS202
|
4.9
|
9.7
|
1.0
|
|
Zinc binding site 6 out
of 12 in 9fgp
Go back to
Zinc Binding Sites List in 9fgp
Zinc binding site 6 out
of 12 in the Cilia and Flagella Associated Protein 299
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Cilia and Flagella Associated Protein 299 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn306
b:8.5
occ:0.50
|
NE2
|
A:HIS134
|
2.0
|
12.8
|
1.0
|
CD2
|
A:HIS134
|
3.0
|
11.5
|
1.0
|
CE1
|
A:HIS134
|
3.0
|
13.6
|
1.0
|
CG2
|
A:THR138
|
3.5
|
21.3
|
1.0
|
ZN
|
A:ZN304
|
3.5
|
12.4
|
0.3
|
CG
|
A:HIS134
|
4.1
|
10.9
|
1.0
|
ND1
|
A:HIS134
|
4.1
|
12.7
|
1.0
|
CG
|
A:PRO174
|
4.6
|
9.0
|
1.0
|
CB
|
A:THR138
|
4.9
|
18.5
|
1.0
|
|
Zinc binding site 7 out
of 12 in 9fgp
Go back to
Zinc Binding Sites List in 9fgp
Zinc binding site 7 out
of 12 in the Cilia and Flagella Associated Protein 299
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Cilia and Flagella Associated Protein 299 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn307
b:49.7
occ:0.50
|
O
|
A:HOH413
|
2.6
|
33.1
|
1.0
|
O
|
A:HOH513
|
2.7
|
24.5
|
1.0
|
CG1
|
A:ILE228
|
2.9
|
27.7
|
1.0
|
CB
|
A:ILE228
|
3.3
|
21.7
|
1.0
|
O
|
A:ASN208
|
3.8
|
8.2
|
1.0
|
ND2
|
A:ASN208
|
3.9
|
11.6
|
1.0
|
CA
|
A:ASN208
|
4.0
|
9.4
|
1.0
|
C
|
A:ASN208
|
4.1
|
9.0
|
1.0
|
CG2
|
A:ILE228
|
4.2
|
21.1
|
1.0
|
CB
|
A:ASN208
|
4.3
|
10.8
|
1.0
|
CD1
|
A:ILE228
|
4.3
|
28.5
|
1.0
|
CA
|
A:ILE228
|
4.4
|
16.8
|
1.0
|
N
|
A:ILE228
|
4.4
|
11.0
|
1.0
|
CG
|
A:ASN208
|
4.5
|
13.3
|
1.0
|
O
|
A:HOH456
|
4.8
|
30.8
|
1.0
|
O
|
A:ILE228
|
4.8
|
26.9
|
1.0
|
|
Zinc binding site 8 out
of 12 in 9fgp
Go back to
Zinc Binding Sites List in 9fgp
Zinc binding site 8 out
of 12 in the Cilia and Flagella Associated Protein 299
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Cilia and Flagella Associated Protein 299 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn301
b:13.8
occ:0.50
|
CD2
|
B:HIS134
|
2.1
|
12.2
|
1.0
|
CD
|
B:LYS137
|
2.8
|
22.9
|
1.0
|
NE2
|
B:HIS134
|
3.0
|
13.0
|
1.0
|
CG
|
B:HIS134
|
3.1
|
11.3
|
1.0
|
CB
|
B:HIS134
|
3.7
|
10.3
|
1.0
|
CE
|
B:LYS137
|
3.8
|
31.3
|
1.0
|
NZ
|
B:LYS137
|
3.8
|
29.9
|
1.0
|
CG
|
B:PRO174
|
3.9
|
10.0
|
1.0
|
CB
|
B:PRO174
|
3.9
|
8.9
|
1.0
|
CA
|
B:HIS134
|
4.0
|
9.6
|
1.0
|
CG
|
B:LYS137
|
4.0
|
27.1
|
1.0
|
CE1
|
B:HIS134
|
4.1
|
12.6
|
1.0
|
ND1
|
B:HIS134
|
4.2
|
13.4
|
1.0
|
CB
|
B:LYS137
|
4.2
|
22.8
|
1.0
|
O
|
B:HIS134
|
4.6
|
9.0
|
1.0
|
C
|
B:HIS134
|
4.8
|
9.0
|
1.0
|
CG2
|
B:THR138
|
4.8
|
21.8
|
1.0
|
CD
|
B:PRO174
|
5.0
|
9.9
|
1.0
|
|
Zinc binding site 9 out
of 12 in 9fgp
Go back to
Zinc Binding Sites List in 9fgp
Zinc binding site 9 out
of 12 in the Cilia and Flagella Associated Protein 299
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 9 of Cilia and Flagella Associated Protein 299 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn302
b:64.5
occ:0.50
|
OE2
|
B:GLU217
|
2.3
|
18.5
|
1.0
|
CD
|
B:GLU217
|
3.5
|
16.7
|
1.0
|
CG
|
B:GLU217
|
3.9
|
14.7
|
1.0
|
OE1
|
B:GLU217
|
4.5
|
19.8
|
1.0
|
|
Zinc binding site 10 out
of 12 in 9fgp
Go back to
Zinc Binding Sites List in 9fgp
Zinc binding site 10 out
of 12 in the Cilia and Flagella Associated Protein 299
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 10 of Cilia and Flagella Associated Protein 299 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn303
b:14.2
occ:0.50
|
OE1
|
B:GLU217
|
2.0
|
19.8
|
1.0
|
CD
|
B:GLU217
|
2.8
|
16.7
|
1.0
|
OE2
|
B:GLU217
|
3.0
|
18.5
|
1.0
|
O
|
B:HOH494
|
4.1
|
28.4
|
1.0
|
CG
|
B:GLU217
|
4.3
|
14.7
|
1.0
|
CB
|
B:GLU217
|
4.7
|
12.4
|
1.0
|
|
Reference:
N.D.Wright,
L.Koekemoer,
E.Williams,
S.Wang,
W.J.Bradshaw,
H.Teare,
Q.Gao,
B.H.Balcomb,
R.Duman,
G.Winter,
R.Keegan,
M.Isupov,
A.Lebedev,
B.Marsden,
F.Von Delft.
Cilia and Flagella Associated Protein 299 To Be Published.
Page generated: Thu Oct 31 15:32:26 2024
|