Zinc in PDB 9cpo: Infectious Bronchitis Virus Core Polymerase Complex

Enzymatic activity of Infectious Bronchitis Virus Core Polymerase Complex

All present enzymatic activity of Infectious Bronchitis Virus Core Polymerase Complex:
2.7.7.48; 2.7.7.50;

Zinc Binding Sites:

The binding sites of Zinc atom in the Infectious Bronchitis Virus Core Polymerase Complex (pdb code 9cpo). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Infectious Bronchitis Virus Core Polymerase Complex, PDB code: 9cpo:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 9cpo

Go back to Zinc Binding Sites List in 9cpo
Zinc binding site 1 out of 2 in the Infectious Bronchitis Virus Core Polymerase Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Infectious Bronchitis Virus Core Polymerase Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1001

b:105.8
occ:1.00
ND1 A:HIS304 2.1 47.8 1.0
HG A:CYS319 2.2 51.1 1.0
SG A:CYS319 2.3 51.1 1.0
SG A:CYS310 2.3 47.3 1.0
SG A:CYS315 2.3 45.2 1.0
HE1 A:HIS304 2.7 47.8 1.0
CE1 A:HIS304 2.7 47.8 1.0
HG A:CYS315 2.8 45.2 1.0
HG A:CYS310 3.1 47.3 1.0
HA A:CYS310 3.2 47.3 1.0
CG A:HIS304 3.4 47.8 1.0
O A:CYS315 3.4 45.2 1.0
HB2 A:CYS319 3.5 51.1 1.0
CB A:CYS310 3.5 47.3 1.0
HB2 A:HIS304 3.5 47.8 1.0
H A:HIS304 3.5 47.8 1.0
CB A:CYS319 3.6 51.1 1.0
HB3 A:CYS310 3.7 47.3 1.0
CA A:CYS310 3.8 47.3 1.0
CB A:CYS315 3.8 45.2 1.0
CB A:HIS304 4.0 47.8 1.0
C A:CYS315 4.0 45.2 1.0
NE2 A:HIS304 4.0 47.8 1.0
HB3 A:CYS315 4.0 45.2 1.0
HB3 A:CYS319 4.0 51.1 1.0
CD2 A:HIS304 4.3 47.8 1.0
N A:HIS304 4.3 47.8 1.0
HB2 A:CYS310 4.3 47.3 1.0
H A:CYS319 4.4 51.1 1.0
HA A:LEU316 4.4 47.1 1.0
CA A:CYS315 4.4 45.2 1.0
N A:CYS310 4.5 47.3 1.0
HB2 A:CYS315 4.5 45.2 1.0
H A:SER311 4.6 45.7 1.0
HA A:CYS315 4.6 45.2 1.0
H A:CYS310 4.7 47.3 1.0
HE2 A:HIS304 4.7 47.8 1.0
CA A:HIS304 4.7 47.8 1.0
N A:LEU316 4.8 47.1 1.0
HB3 A:HIS304 4.8 47.8 1.0
HA A:TYR303 4.8 45.9 1.0
O A:HIS304 4.8 47.8 1.0
CA A:CYS319 4.8 51.1 1.0
HA A:CYS307 4.8 46.2 1.0
N A:CYS319 4.9 51.1 1.0

Zinc binding site 2 out of 2 in 9cpo

Go back to Zinc Binding Sites List in 9cpo
Zinc binding site 2 out of 2 in the Infectious Bronchitis Virus Core Polymerase Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Infectious Bronchitis Virus Core Polymerase Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1002

b:82.5
occ:1.00
ND1 A:HIS650 2.1 48.7 1.0
SG A:CYS496 2.3 50.8 1.0
SG A:CYS654 2.3 55.0 1.0
SG A:CYS653 2.3 59.2 1.0
CE1 A:HIS650 3.0 48.7 1.0
HG A:CYS496 3.0 50.8 1.0
HB3 A:HIS650 3.0 48.7 1.0
HE1 A:HIS650 3.1 48.7 1.0
HG A:CYS654 3.1 55.0 1.0
CG A:HIS650 3.2 48.7 1.0
HB2 A:CYS653 3.3 59.2 1.0
HG A:CYS653 3.3 59.2 1.0
HE1 A:PHE579 3.3 46.6 1.0
CB A:CYS653 3.4 59.2 1.0
HB2 A:CYS654 3.5 55.0 1.0
CB A:HIS650 3.6 48.7 1.0
CB A:CYS654 3.6 55.0 1.0
CB A:CYS496 3.8 50.8 1.0
HB2 A:CYS496 3.8 50.8 1.0
H A:CYS496 3.9 50.8 1.0
N A:CYS654 4.0 55.0 1.0
CE1 A:PHE579 4.1 46.6 1.0
H A:CYS654 4.1 55.0 1.0
NE2 A:HIS650 4.1 48.7 1.0
C A:CYS653 4.1 59.2 1.0
HB3 A:CYS653 4.1 59.2 1.0
HB2 A:HIS650 4.2 48.7 1.0
N A:CYS496 4.2 50.8 1.0
CD2 A:HIS650 4.2 48.7 1.0
HB3 A:CYS654 4.3 55.0 1.0
CA A:CYS653 4.4 59.2 1.0
CA A:CYS654 4.4 55.0 1.0
HA2 A:GLY495 4.4 46.5 1.0
HD1 A:PHE579 4.4 46.6 1.0
HB3 A:CYS496 4.5 50.8 1.0
HA A:HIS650 4.5 48.7 1.0
HE2 A:LYS540 4.5 47.0 1.0
CA A:CYS496 4.5 50.8 1.0
HZ2 A:LYS540 4.6 47.0 1.0
O A:CYS653 4.6 59.2 1.0
HZ3 A:LYS540 4.7 47.0 1.0
CD1 A:PHE579 4.7 46.6 1.0
CA A:HIS650 4.7 48.7 1.0
H A:CYS653 4.7 59.2 1.0
HA A:CYS496 4.8 50.8 1.0
HA A:CYS654 4.8 55.0 1.0
C A:GLY495 4.8 46.5 1.0
HE2 A:HIS650 4.9 48.7 1.0
HZ A:PHE579 5.0 46.6 1.0
CZ A:PHE579 5.0 46.6 1.0
N A:CYS653 5.0 59.2 1.0
NZ A:LYS540 5.0 47.0 1.0

Reference:

P.J.Hoferle, T.K.Anderson, R.N.Kirchdoerfer. A Genus-Specific NSP12 Region Impacts Polymerase Assembly in Alpha- and Gammacoronaviruses Biorxiv 2024.
ISSN: ISSN 2692-8205
DOI: 10.1101/2024.07.23.604833
Page generated: Thu Oct 31 15:26:03 2024

Last articles

Zn in 9FD2
Zn in 9GUW
Zn in 9GUX
Zn in 9F7C
Zn in 9GUR
Zn in 9F7A
Zn in 9DDE
Zn in 9DBY
Zn in 9EBZ
Zn in 9DGG
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy