Zinc in PDB 9b0b: Structure of Optineurin Bound to Hoip NZF1 Domain

All present enzymatic activity of Structure of Optineurin Bound to Hoip NZF1 Domain:
2.3.2.31;

The structure of Structure of Optineurin Bound to Hoip NZF1 Domain, PDB code: 9b0b was solved by M.A.Michel, S.Scutts, D.Komander, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	58.27 / 1.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	49.755, 92.684, 149.84, 90, 90, 90
R / Rfree (%)	19.6 / 22.2

The binding sites of Zinc atom in the Structure of Optineurin Bound to Hoip NZF1 Domain (pdb code 9b0b). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Optineurin Bound to Hoip NZF1 Domain, PDB code: 9b0b:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Optineurin Bound to Hoip NZF1 Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Optineurin Bound to Hoip NZF1 Domain within 5.0Å range: probe atom residue distance (Å) B Occ G:Zn401 b:17.8 occ:1.00 SG G:CYS370 2.1 18.4 1.0 SG G:CYS373 2.3 18.2 1.0 SG G:CYS359 2.3 18.1 1.0 SG G:CYS356 2.3 18.1 1.0 CB G:CYS356 3.1 21.1 1.0 CB G:CYS370 3.1 15.9 1.0 CB G:CYS359 3.3 19.2 1.0 CB G:CYS373 3.4 21.7 1.0 N G:CYS373 3.7 20.5 1.0 N G:CYS359 3.9 17.4 1.0 CA G:CYS373 4.1 20.6 1.0 CA G:CYS359 4.1 18.1 1.0 CB G:ILE372 4.3 22.7 1.0 CA G:CYS356 4.6 20.1 1.0 CA G:CYS370 4.6 17.6 1.0 O G:HOH512 4.6 24.4 1.0 C G:ILE372 4.8 22.2 1.0 C G:CYS359 4.8 20.6 1.0 C G:CYS373 4.8 19.6 1.0 N G:ILE372 4.9 24.1 1.0 CB G:SER358 4.9 19.5 0.7 CB G:SER358 4.9 20.0 0.3 CA G:ILE372 4.9 22.4 1.0 N G:THR360 5.0 17.6 1.0 CB G:PHE361 5.0 22.9 1.0 N G:GLU374 5.0 18.7 1.0 C G:SER358 5.0 21.9 1.0

Zinc binding site 2 out of 2 in the Structure of Optineurin Bound to Hoip NZF1 Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Optineurin Bound to Hoip NZF1 Domain within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn401 b:18.0 occ:1.00 SG E:CYS370 2.3 18.6 1.0 SG E:CYS373 2.3 17.7 1.0 SG E:CYS359 2.3 18.3 1.0 SG E:CYS356 2.4 17.4 1.0 CB E:CYS356 3.1 18.6 1.0 CB E:CYS370 3.2 13.5 1.0 CB E:CYS359 3.3 20.0 1.0 CB E:CYS373 3.4 21.5 1.0 OG E:SER358 3.6 16.9 0.2 N E:CYS373 3.8 18.8 1.0 N E:CYS359 3.8 17.9 1.0 CA E:CYS359 4.1 20.2 1.0 CA E:CYS373 4.2 19.3 1.0 CB E:ILE372 4.4 19.7 1.0 CA E:CYS356 4.6 19.1 1.0 CA E:CYS370 4.6 16.6 1.0 O E:HOH503 4.7 49.7 1.0 O E:HOH514 4.7 26.6 1.0 C E:ILE372 4.8 22.6 1.0 C E:CYS359 4.8 18.2 1.0 CB E:PHE361 4.9 20.1 1.0 N E:ILE372 4.9 21.4 1.0 CB E:SER358 4.9 17.2 0.4 CB E:SER358 4.9 17.5 0.2 N E:THR360 4.9 18.0 1.0 C E:CYS373 4.9 19.0 1.0 CA E:ILE372 4.9 19.6 1.0 CB E:SER358 4.9 17.1 0.5 C E:SER358 5.0 22.0 1.0 N E:GLU374 5.0 18.5 1.0

M.A.Michel, S.Scutts, D.Komander. Linkage and Substrate Specificity Conferred By Nzf Ubiquitin Binding Domains To Be Published.