Zinc in PDB 8waz: De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss
Enzymatic activity of De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss
All present enzymatic activity of De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss:
2.7.7.6;
3.6.4.12;
Other elements in 8waz:
The structure of De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss
(pdb code 8waz). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the
De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss, PDB code: 8waz:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Zinc binding site 1 out
of 8 in 8waz
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Zinc Binding Sites List in 8waz
Zinc binding site 1 out
of 8 in the De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
o:Zn2001
b:126.1
occ:1.00
|
NE2
|
o:HIS84
|
2.1
|
127.0
|
1.0
|
SG
|
o:CYS71
|
2.3
|
141.6
|
1.0
|
SG
|
o:CYS74
|
2.3
|
137.3
|
1.0
|
SG
|
o:CYS81
|
2.3
|
138.7
|
1.0
|
CE1
|
o:HIS84
|
3.0
|
127.0
|
1.0
|
CD2
|
o:HIS84
|
3.1
|
127.0
|
1.0
|
OG1
|
o:THR73
|
3.3
|
132.3
|
1.0
|
CB
|
o:CYS81
|
3.5
|
138.7
|
1.0
|
CB
|
o:CYS74
|
3.8
|
137.3
|
1.0
|
CB
|
o:CYS71
|
3.8
|
141.6
|
1.0
|
N
|
o:CYS74
|
3.9
|
136.6
|
1.0
|
ND1
|
o:HIS84
|
4.1
|
127.0
|
1.0
|
O
|
o:CYS74
|
4.1
|
136.6
|
1.0
|
CG
|
o:HIS84
|
4.2
|
127.0
|
1.0
|
CA
|
o:CYS74
|
4.3
|
136.6
|
1.0
|
CA
|
o:CYS81
|
4.3
|
136.2
|
1.0
|
C
|
o:CYS74
|
4.5
|
136.6
|
1.0
|
CB
|
o:THR73
|
4.5
|
132.3
|
1.0
|
C
|
o:THR73
|
4.8
|
134.0
|
1.0
|
CD
|
o:PRO82
|
4.9
|
128.1
|
1.0
|
N
|
o:GLY83
|
4.9
|
128.4
|
1.0
|
CG2
|
o:VAL64
|
5.0
|
146.2
|
1.0
|
|
Zinc binding site 2 out
of 8 in 8waz
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Zinc Binding Sites List in 8waz
Zinc binding site 2 out
of 8 in the De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
o:Zn2002
b:126.1
occ:1.00
|
SG
|
o:CYS184
|
2.3
|
171.8
|
1.0
|
SG
|
o:CYS111
|
2.3
|
164.4
|
1.0
|
SG
|
o:CYS114
|
2.3
|
163.7
|
1.0
|
CB
|
o:CYS114
|
2.3
|
163.7
|
1.0
|
O
|
o:GLY183
|
3.2
|
175.3
|
1.0
|
SG
|
o:CYS154
|
3.4
|
174.7
|
1.0
|
CB
|
o:CYS184
|
3.4
|
171.8
|
1.0
|
CB
|
o:CYS111
|
3.5
|
164.4
|
1.0
|
CA
|
o:CYS114
|
3.8
|
156.0
|
1.0
|
CB
|
o:CYS154
|
3.9
|
174.7
|
1.0
|
O
|
o:CYS184
|
4.0
|
172.2
|
1.0
|
C
|
o:GLY183
|
4.3
|
175.3
|
1.0
|
CA
|
o:CYS184
|
4.4
|
172.2
|
1.0
|
O
|
o:PHE112
|
4.4
|
152.2
|
1.0
|
N
|
o:CYS114
|
4.5
|
156.0
|
1.0
|
NE2
|
o:GLN188
|
4.5
|
158.9
|
1.0
|
C
|
o:CYS184
|
4.5
|
172.2
|
1.0
|
C
|
o:CYS114
|
4.8
|
156.0
|
1.0
|
N
|
o:CYS184
|
4.8
|
172.2
|
1.0
|
CA
|
o:CYS111
|
4.8
|
151.6
|
1.0
|
|
Zinc binding site 3 out
of 8 in 8waz
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Zinc Binding Sites List in 8waz
Zinc binding site 3 out
of 8 in the De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
p:Zn1202
b:126.1
occ:1.00
|
SG
|
p:CYS1137
|
2.3
|
148.7
|
1.0
|
SG
|
p:CYS1122
|
2.3
|
142.6
|
1.0
|
SG
|
p:CYS1140
|
2.3
|
153.0
|
1.0
|
SG
|
p:CYS1119
|
2.3
|
141.6
|
1.0
|
CB
|
p:CYS1119
|
3.0
|
141.6
|
1.0
|
CB
|
p:CYS1122
|
3.4
|
142.6
|
1.0
|
CB
|
p:CYS1140
|
3.5
|
153.0
|
1.0
|
CB
|
p:CYS1137
|
3.6
|
148.7
|
1.0
|
N
|
p:CYS1122
|
3.6
|
134.3
|
1.0
|
O
|
p:CYS1122
|
4.0
|
134.3
|
1.0
|
CA
|
p:CYS1122
|
4.0
|
134.3
|
1.0
|
C
|
p:CYS1122
|
4.4
|
134.3
|
1.0
|
N
|
p:CYS1140
|
4.5
|
144.2
|
1.0
|
CA
|
p:CYS1119
|
4.5
|
135.0
|
1.0
|
CA
|
p:CYS1140
|
4.7
|
144.2
|
1.0
|
CB
|
p:LEU1121
|
4.7
|
131.9
|
1.0
|
CB
|
p:ASN1142
|
4.7
|
141.6
|
1.0
|
O
|
p:ARG1138
|
4.7
|
140.2
|
1.0
|
C
|
p:LEU1121
|
4.8
|
132.4
|
1.0
|
CA
|
p:CYS1137
|
4.9
|
138.5
|
1.0
|
ND2
|
p:ASN1142
|
4.9
|
141.6
|
1.0
|
|
Zinc binding site 4 out
of 8 in 8waz
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Zinc Binding Sites List in 8waz
Zinc binding site 4 out
of 8 in the De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
q:Zn301
b:126.1
occ:1.00
|
SG
|
q:CYS94
|
2.3
|
133.0
|
1.0
|
SG
|
q:CYS97
|
2.3
|
132.4
|
1.0
|
SG
|
q:CYS88
|
2.3
|
138.1
|
1.0
|
SG
|
q:CYS90
|
2.3
|
147.2
|
1.0
|
CB
|
q:CYS94
|
2.9
|
133.0
|
1.0
|
CB
|
q:CYS97
|
3.5
|
132.4
|
1.0
|
N
|
q:CYS94
|
3.5
|
122.6
|
1.0
|
CB
|
q:CYS88
|
3.5
|
138.1
|
1.0
|
CB
|
q:CYS90
|
3.6
|
147.2
|
1.0
|
CA
|
q:CYS94
|
3.7
|
122.6
|
1.0
|
N
|
q:CYS97
|
3.9
|
117.8
|
1.0
|
C
|
q:CYS94
|
4.2
|
122.6
|
1.0
|
C
|
q:PHE93
|
4.2
|
128.4
|
1.0
|
CA
|
q:CYS97
|
4.3
|
117.8
|
1.0
|
O
|
q:CYS94
|
4.4
|
122.6
|
1.0
|
N
|
q:CYS90
|
4.5
|
143.5
|
1.0
|
CA
|
q:CYS90
|
4.5
|
143.5
|
1.0
|
CA
|
q:PHE93
|
4.6
|
128.4
|
1.0
|
O
|
q:CYS90
|
4.6
|
143.5
|
1.0
|
O
|
q:GLU92
|
4.7
|
134.8
|
1.0
|
CB
|
q:GLU96
|
4.8
|
131.8
|
1.0
|
N
|
q:GLU96
|
4.8
|
122.0
|
1.0
|
C
|
q:CYS90
|
4.8
|
143.5
|
1.0
|
C
|
q:GLU96
|
4.9
|
122.0
|
1.0
|
CA
|
q:CYS88
|
4.9
|
140.3
|
1.0
|
|
Zinc binding site 5 out
of 8 in 8waz
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Zinc Binding Sites List in 8waz
Zinc binding site 5 out
of 8 in the De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
w:Zn201
b:126.1
occ:1.00
|
SG
|
w:CYS20
|
2.3
|
163.9
|
1.0
|
SG
|
w:CYS42
|
2.3
|
167.8
|
1.0
|
SG
|
w:CYS39
|
2.3
|
169.3
|
1.0
|
SG
|
w:CYS17
|
2.3
|
161.5
|
1.0
|
CB
|
w:CYS39
|
2.8
|
169.3
|
1.0
|
CB
|
w:CYS17
|
3.1
|
161.5
|
1.0
|
CB
|
w:CYS42
|
3.8
|
167.8
|
1.0
|
CB
|
w:CYS20
|
4.0
|
163.9
|
1.0
|
N
|
w:CYS20
|
4.1
|
156.2
|
1.0
|
N
|
w:CYS42
|
4.3
|
163.9
|
1.0
|
CA
|
w:CYS39
|
4.3
|
161.3
|
1.0
|
CA
|
w:CYS17
|
4.6
|
153.9
|
1.0
|
CA
|
w:CYS20
|
4.6
|
156.2
|
1.0
|
CA
|
w:CYS42
|
4.6
|
163.9
|
1.0
|
CB
|
w:TYR44
|
4.7
|
153.5
|
1.0
|
CB
|
w:GLU19
|
4.7
|
158.2
|
1.0
|
CB
|
w:ASN22
|
4.8
|
154.4
|
1.0
|
ND2
|
w:ASN22
|
4.8
|
154.4
|
1.0
|
C
|
w:CYS39
|
4.9
|
161.3
|
1.0
|
C
|
w:ASN41
|
4.9
|
162.3
|
1.0
|
N
|
w:ASN22
|
5.0
|
153.2
|
1.0
|
OE1
|
w:GLU19
|
5.0
|
158.2
|
1.0
|
|
Zinc binding site 6 out
of 8 in 8waz
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Zinc Binding Sites List in 8waz
Zinc binding site 6 out
of 8 in the De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
w:Zn202
b:126.1
occ:1.00
|
SG
|
w:CYS119
|
2.3
|
152.4
|
1.0
|
SG
|
w:CYS89
|
2.3
|
155.6
|
1.0
|
SG
|
w:CYS86
|
2.3
|
150.4
|
1.0
|
SG
|
w:CYS114
|
2.3
|
146.3
|
1.0
|
CB
|
w:CYS86
|
2.8
|
150.4
|
1.0
|
CB
|
w:CYS114
|
3.3
|
146.3
|
1.0
|
CB
|
w:CYS119
|
3.4
|
152.4
|
1.0
|
CB
|
w:CYS89
|
3.8
|
155.6
|
1.0
|
N
|
w:CYS89
|
4.0
|
150.2
|
1.0
|
CA
|
w:CYS86
|
4.3
|
144.4
|
1.0
|
CB
|
w:HIS91
|
4.4
|
143.6
|
1.0
|
CA
|
w:CYS89
|
4.4
|
150.2
|
1.0
|
CB
|
w:HIS121
|
4.6
|
136.5
|
1.0
|
N
|
w:HIS91
|
4.7
|
143.4
|
1.0
|
O
|
w:THR115
|
4.7
|
137.4
|
1.0
|
CA
|
w:CYS114
|
4.7
|
133.3
|
1.0
|
CA
|
w:CYS119
|
4.8
|
143.7
|
1.0
|
CB
|
w:LYS88
|
4.8
|
142.6
|
1.0
|
N
|
w:GLY90
|
4.8
|
146.3
|
1.0
|
C
|
w:CYS89
|
4.9
|
150.2
|
1.0
|
N
|
w:LYS88
|
5.0
|
146.1
|
1.0
|
C
|
w:CYS86
|
5.0
|
144.4
|
1.0
|
|
Zinc binding site 7 out
of 8 in 8waz
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Zinc Binding Sites List in 8waz
Zinc binding site 7 out
of 8 in the De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
x:Zn101
b:126.1
occ:1.00
|
SG
|
x:CYS10
|
2.3
|
95.3
|
1.0
|
SG
|
x:CYS45
|
2.3
|
108.2
|
1.0
|
SG
|
x:CYS44
|
2.3
|
107.5
|
1.0
|
SG
|
x:CYS7
|
2.3
|
98.6
|
1.0
|
CB
|
x:CYS7
|
3.1
|
98.6
|
1.0
|
N
|
x:CYS45
|
3.2
|
97.0
|
1.0
|
CB
|
x:CYS10
|
3.5
|
95.3
|
1.0
|
CB
|
x:CYS44
|
3.5
|
107.5
|
1.0
|
CB
|
x:CYS45
|
3.5
|
108.2
|
1.0
|
CA
|
x:CYS45
|
3.5
|
97.0
|
1.0
|
C
|
x:CYS44
|
3.6
|
97.9
|
1.0
|
N
|
x:CYS10
|
3.8
|
93.8
|
1.0
|
CA
|
x:CYS44
|
4.2
|
97.9
|
1.0
|
CA
|
x:CYS10
|
4.2
|
93.8
|
1.0
|
O
|
x:CYS44
|
4.2
|
97.9
|
1.0
|
NE
|
x:ARG42
|
4.3
|
100.3
|
1.0
|
CA
|
x:CYS7
|
4.6
|
91.5
|
1.0
|
CB
|
x:THR9
|
4.6
|
92.6
|
1.0
|
NH2
|
x:ARG42
|
4.7
|
100.3
|
1.0
|
N
|
x:GLY11
|
4.7
|
93.3
|
1.0
|
C
|
x:THR9
|
4.8
|
91.2
|
1.0
|
C
|
x:CYS7
|
4.9
|
91.5
|
1.0
|
N
|
x:THR9
|
4.9
|
91.2
|
1.0
|
N
|
x:CYS44
|
4.9
|
97.9
|
1.0
|
C
|
x:CYS10
|
5.0
|
93.8
|
1.0
|
CB
|
x:ARG42
|
5.0
|
100.3
|
1.0
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Zinc binding site 8 out
of 8 in 8waz
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Zinc Binding Sites List in 8waz
Zinc binding site 8 out
of 8 in the De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss
Mono view
Stereo pair view
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A full contact list of Zinc with other atoms in the Zn binding
site number 8 of De Novo Transcribing Complex 16 (TC16), the Early Elongation Complex with Pol II Positioned 16NT Downstream of Tss within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
z:Zn101
b:126.1
occ:1.00
|
SG
|
z:CYS39
|
2.3
|
150.7
|
1.0
|
SG
|
z:CYS19
|
2.3
|
146.6
|
1.0
|
SG
|
z:CYS22
|
2.3
|
145.8
|
1.0
|
SG
|
z:CYS36
|
2.3
|
153.0
|
1.0
|
CB
|
z:CYS19
|
2.8
|
146.6
|
1.0
|
CB
|
z:CYS36
|
2.9
|
153.0
|
1.0
|
CB
|
z:CYS39
|
3.4
|
150.7
|
1.0
|
CB
|
z:CYS22
|
3.6
|
145.8
|
1.0
|
OG1
|
z:THR24
|
3.9
|
140.9
|
1.0
|
N
|
z:CYS22
|
4.1
|
140.7
|
1.0
|
CA
|
z:CYS19
|
4.3
|
135.2
|
1.0
|
CA
|
z:CYS36
|
4.4
|
148.9
|
1.0
|
CA
|
z:CYS22
|
4.4
|
140.7
|
1.0
|
O
|
z:ARG37
|
4.5
|
150.1
|
1.0
|
CA
|
z:CYS39
|
4.5
|
151.2
|
1.0
|
N
|
z:CYS39
|
4.6
|
151.2
|
1.0
|
CB
|
z:TYR41
|
4.7
|
143.2
|
1.0
|
CE
|
z:MET44
|
4.7
|
136.6
|
1.0
|
C
|
z:CYS36
|
4.8
|
148.9
|
1.0
|
O
|
z:THR24
|
4.8
|
139.0
|
1.0
|
C
|
z:CYS22
|
4.8
|
140.7
|
1.0
|
ND2
|
z:ASN26
|
4.8
|
139.2
|
1.0
|
N
|
z:HIS23
|
4.9
|
140.8
|
1.0
|
N
|
z:TYR41
|
4.9
|
145.1
|
1.0
|
N
|
z:GLY40
|
5.0
|
148.8
|
1.0
|
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Reference:
X.Chen,
W.Liu,
Q.Wang,
X.Wang,
Y.Ren,
X.Qu,
W.Li,
Y.Xu.
Structural Visualization of De Novo Transcription Initiation. Science.
ISSN: ESSN 1095-9203
Page generated: Thu Oct 31 13:22:42 2024
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