Zinc in PDB 8vy3: Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio)

All present enzymatic activity of Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio):
2.7.7.102; 2.7.7.7;

The structure of Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio) also contains other interesting chemical elements:

Iron

(Fe)

4 atoms

The binding sites of Zinc atom in the Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio) (pdb code 8vy3). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio), PDB code: 8vy3:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:119.6 occ:1.00 SG A:CYS131 2.3 76.0 1.0 SG A:CYS128 2.3 62.5 1.0 SG A:CYS122 2.3 72.4 1.0 SG A:CYS121 2.3 82.5 1.0 CB A:CYS131 3.1 60.0 1.0 CB A:CYS121 3.6 77.7 1.0 CB A:CYS128 3.6 56.2 1.0 N A:CYS128 3.7 54.4 1.0 CB A:CYS122 3.8 70.7 1.0 N A:CYS122 3.9 69.1 1.0 N A:CYS131 4.1 62.6 1.0 O A:CYS128 4.1 55.8 1.0 CA A:CYS128 4.1 54.0 1.0 CA A:CYS131 4.2 60.9 1.0 C A:CYS121 4.2 76.9 1.0 C A:CYS128 4.5 54.1 1.0 C A:ILE127 4.5 58.1 1.0 CA A:CYS121 4.5 78.1 1.0 CA A:CYS122 4.5 70.5 1.0 CA A:ILE127 4.7 57.8 1.0 O A:CYS121 4.8 77.4 1.0 CG A:LYS130 4.8 63.9 1.0

Zinc binding site 2 out of 3 in the Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn1501 b:150.1 occ:1.00 SG C:CYS1286 2.3 106.5 1.0 SG C:CYS1315 2.3 111.7 1.0 SG C:CYS1310 2.3 101.1 1.0 SG C:CYS1283 2.3 99.9 1.0 CB C:CYS1315 3.1 111.1 1.0 CB C:CYS1283 3.1 94.4 1.0 CB C:CYS1310 3.3 98.0 1.0 CB C:CYS1286 3.5 101.5 1.0 N C:CYS1286 4.1 99.8 1.0 CA C:CYS1286 4.4 101.5 1.0 CB C:ASN1312 4.5 106.0 1.0 CA C:CYS1315 4.5 112.9 1.0 CA C:CYS1283 4.6 95.5 1.0 CA C:CYS1310 4.8 97.8 1.0 CB C:ALA1317 4.9 95.5 1.0 O C:ALA1317 4.9 98.7 1.0

Zinc binding site 3 out of 3 in the Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn1502 b:92.9 occ:1.00 SG C:CYS1348 2.3 40.3 1.0 SG C:CYS1353 2.3 52.7 1.0 SG C:CYS1371 2.3 44.0 1.0 SG C:CYS1374 2.6 50.8 1.0 CB C:CYS1348 3.0 24.9 1.0 CB C:CYS1371 3.2 33.1 1.0 CB C:CYS1353 3.2 35.5 1.0 CB C:CYS1374 4.0 50.4 1.0 CB C:ALA1377 4.1 47.0 1.0 N C:CYS1374 4.1 48.5 1.0 O C:CYS1374 4.2 62.1 1.0 CB C:ASN1355 4.2 31.4 1.0 CA C:CYS1348 4.4 27.0 1.0 CA C:CYS1374 4.5 45.9 1.0 N C:ASN1355 4.6 37.7 1.0 CA C:CYS1371 4.6 30.6 1.0 CA C:CYS1353 4.7 34.1 1.0 C C:CYS1374 4.8 53.0 1.0 CB C:ALA1373 4.9 44.2 1.0 N C:ARG1354 4.9 33.7 1.0 C C:CYS1353 5.0 37.1 1.0

K.M.Abe, G.Li, T.Grant, C.J.Lim. Human PRC2 - AAVLEA1 (1:40 Molar Ratio) To Be Published.