Zinc in PDB 8tnp: Cryo-Em Structure of DDB1DB:Crbn:Pomalidomide:SD40
Zinc Binding Sites:
The binding sites of Zinc atom in the Cryo-Em Structure of DDB1DB:Crbn:Pomalidomide:SD40
(pdb code 8tnp). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the
Cryo-Em Structure of DDB1DB:Crbn:Pomalidomide:SD40, PDB code: 8tnp:
Jump to Zinc binding site number:
1;
2;
Zinc binding site 1 out
of 2 in 8tnp
Go back to
Zinc Binding Sites List in 8tnp
Zinc binding site 1 out
of 2 in the Cryo-Em Structure of DDB1DB:Crbn:Pomalidomide:SD40
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Cryo-Em Structure of DDB1DB:Crbn:Pomalidomide:SD40 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn501
b:197.3
occ:1.00
|
SG
|
B:CYS394
|
2.3
|
157.3
|
1.0
|
SG
|
B:CYS391
|
2.3
|
153.8
|
1.0
|
SG
|
B:CYS326
|
2.3
|
151.6
|
1.0
|
SG
|
B:CYS323
|
2.3
|
149.0
|
1.0
|
HB3
|
B:CYS394
|
3.0
|
157.3
|
1.0
|
H
|
B:CYS326
|
3.1
|
151.6
|
1.0
|
H
|
B:CYS394
|
3.1
|
157.3
|
1.0
|
CB
|
B:CYS394
|
3.2
|
157.3
|
1.0
|
HB3
|
B:CYS323
|
3.4
|
149.0
|
1.0
|
CB
|
B:CYS323
|
3.4
|
149.0
|
1.0
|
HB2
|
B:CYS323
|
3.5
|
149.0
|
1.0
|
HB3
|
B:GLN325
|
3.5
|
151.9
|
1.0
|
HB2
|
B:CYS326
|
3.6
|
151.6
|
1.0
|
CB
|
B:CYS326
|
3.6
|
151.6
|
1.0
|
N
|
B:CYS394
|
3.8
|
157.3
|
1.0
|
N
|
B:CYS326
|
3.8
|
151.6
|
1.0
|
CB
|
B:CYS391
|
3.8
|
153.8
|
1.0
|
HB2
|
B:SER396
|
3.9
|
153.5
|
1.0
|
HB3
|
B:CYS391
|
3.9
|
153.8
|
1.0
|
CA
|
B:CYS394
|
4.0
|
157.3
|
1.0
|
HB
|
B:ILE393
|
4.0
|
152.1
|
1.0
|
H
|
B:SER396
|
4.0
|
153.5
|
1.0
|
HB2
|
B:CYS394
|
4.0
|
157.3
|
1.0
|
HB2
|
B:CYS391
|
4.1
|
153.8
|
1.0
|
HG
|
B:SER396
|
4.2
|
153.5
|
1.0
|
HD11
|
B:ILE398
|
4.3
|
147.0
|
1.0
|
CA
|
B:CYS326
|
4.3
|
151.6
|
1.0
|
HB3
|
B:CYS326
|
4.4
|
151.6
|
1.0
|
CB
|
B:GLN325
|
4.4
|
151.9
|
1.0
|
H
|
B:ALA395
|
4.5
|
155.2
|
1.0
|
HB2
|
B:GLN325
|
4.5
|
151.9
|
1.0
|
H
|
B:GLN325
|
4.5
|
151.9
|
1.0
|
C
|
B:CYS394
|
4.5
|
157.3
|
1.0
|
H
|
B:ILE393
|
4.6
|
152.1
|
1.0
|
OG
|
B:SER396
|
4.6
|
153.5
|
1.0
|
CB
|
B:SER396
|
4.7
|
153.5
|
1.0
|
HA
|
B:CYS326
|
4.7
|
151.6
|
1.0
|
N
|
B:ALA395
|
4.7
|
155.2
|
1.0
|
HG22
|
B:ILE393
|
4.7
|
152.1
|
1.0
|
C
|
B:GLN325
|
4.8
|
151.9
|
1.0
|
N
|
B:SER396
|
4.8
|
153.5
|
1.0
|
CA
|
B:CYS323
|
4.8
|
149.0
|
1.0
|
C
|
B:ILE393
|
4.8
|
152.1
|
1.0
|
HA
|
B:CYS394
|
4.9
|
157.3
|
1.0
|
CB
|
B:ILE393
|
4.9
|
152.1
|
1.0
|
HB
|
B:THR329
|
4.9
|
148.6
|
1.0
|
HG1
|
B:THR329
|
5.0
|
148.6
|
1.0
|
CA
|
B:GLN325
|
5.0
|
151.9
|
1.0
|
|
Zinc binding site 2 out
of 2 in 8tnp
Go back to
Zinc Binding Sites List in 8tnp
Zinc binding site 2 out
of 2 in the Cryo-Em Structure of DDB1DB:Crbn:Pomalidomide:SD40
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Cryo-Em Structure of DDB1DB:Crbn:Pomalidomide:SD40 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn101
b:190.0
occ:1.00
|
NE2
|
C:HIS35
|
2.0
|
167.1
|
1.0
|
NE2
|
C:HIS39
|
2.0
|
162.2
|
1.0
|
SG
|
C:CYS22
|
2.3
|
158.9
|
1.0
|
SG
|
C:CYS19
|
2.3
|
160.2
|
1.0
|
H
|
C:CYS22
|
2.5
|
158.9
|
1.0
|
HB3
|
C:CYS22
|
2.5
|
158.9
|
1.0
|
CB
|
C:CYS22
|
2.8
|
158.9
|
1.0
|
CE1
|
C:HIS35
|
2.9
|
167.1
|
1.0
|
CD2
|
C:HIS39
|
3.0
|
162.2
|
1.0
|
HE1
|
C:HIS35
|
3.0
|
167.1
|
1.0
|
HB
|
C:ILE21
|
3.0
|
158.8
|
1.0
|
CE1
|
C:HIS39
|
3.1
|
162.2
|
1.0
|
CD2
|
C:HIS35
|
3.1
|
167.1
|
1.0
|
HD2
|
C:HIS39
|
3.1
|
162.2
|
1.0
|
N
|
C:CYS22
|
3.1
|
158.9
|
1.0
|
HE1
|
C:HIS39
|
3.3
|
162.2
|
1.0
|
HD2
|
C:HIS35
|
3.3
|
167.1
|
1.0
|
HB3
|
C:CYS19
|
3.5
|
160.2
|
1.0
|
CB
|
C:CYS19
|
3.5
|
160.2
|
1.0
|
CA
|
C:CYS22
|
3.5
|
158.9
|
1.0
|
HB2
|
C:CYS22
|
3.7
|
158.9
|
1.0
|
HB2
|
C:CYS19
|
3.8
|
160.2
|
1.0
|
H
|
C:PHE24
|
3.8
|
160.4
|
1.0
|
H
|
C:ILE21
|
3.9
|
158.8
|
1.0
|
CB
|
C:ILE21
|
4.0
|
158.8
|
1.0
|
ND1
|
C:HIS35
|
4.0
|
167.1
|
1.0
|
HB2
|
C:PHE24
|
4.1
|
160.4
|
1.0
|
HB3
|
C:PHE24
|
4.1
|
160.4
|
1.0
|
CG
|
C:HIS35
|
4.1
|
167.1
|
1.0
|
CG
|
C:HIS39
|
4.1
|
162.2
|
1.0
|
ND1
|
C:HIS39
|
4.1
|
162.2
|
1.0
|
H
|
C:GLY23
|
4.2
|
156.9
|
1.0
|
C
|
C:ILE21
|
4.2
|
158.8
|
1.0
|
HD12
|
C:ILE21
|
4.2
|
158.8
|
1.0
|
HB2
|
B:HIS397
|
4.3
|
148.7
|
1.0
|
HA
|
C:CYS22
|
4.3
|
158.9
|
1.0
|
C
|
C:CYS22
|
4.4
|
158.9
|
1.0
|
HG13
|
C:ILE21
|
4.4
|
158.8
|
1.0
|
CA
|
C:ILE21
|
4.5
|
158.8
|
1.0
|
N
|
C:GLY23
|
4.5
|
156.9
|
1.0
|
CB
|
C:PHE24
|
4.5
|
160.4
|
1.0
|
N
|
C:ILE21
|
4.5
|
158.8
|
1.0
|
CG1
|
C:ILE21
|
4.7
|
158.8
|
1.0
|
HA
|
C:ILE36
|
4.7
|
166.0
|
1.0
|
HB3
|
B:HIS397
|
4.7
|
148.7
|
1.0
|
N
|
C:PHE24
|
4.7
|
160.4
|
1.0
|
HD1
|
C:HIS35
|
4.7
|
167.1
|
1.0
|
HG13
|
C:ILE36
|
4.8
|
166.0
|
1.0
|
HG21
|
C:ILE21
|
4.8
|
158.8
|
1.0
|
CA
|
C:CYS19
|
4.8
|
160.2
|
1.0
|
CB
|
B:HIS397
|
4.9
|
148.7
|
1.0
|
CG2
|
C:ILE21
|
4.9
|
158.8
|
1.0
|
HD1
|
C:HIS39
|
4.9
|
162.2
|
1.0
|
CD1
|
C:ILE21
|
4.9
|
158.8
|
1.0
|
HG22
|
C:ILE21
|
4.9
|
158.8
|
1.0
|
|
Reference:
S.S.Roy Burman,
S.S.Roy Burman,
M.Hunkeler,
E.S.Fischer.
N/A N/A.
Page generated: Thu Oct 31 11:38:12 2024
|