Zinc in PDB 8rsl: Crystal Structure of Staphylococcus Aureus Macrodomain

The structure of Crystal Structure of Staphylococcus Aureus Macrodomain, PDB code: 8rsl was solved by A.Ariza, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.08 / 1.94
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	40.19, 139.4, 49.19, 90, 93.76, 90
R / Rfree (%)	16.4 / 21.3

The binding sites of Zinc atom in the Crystal Structure of Staphylococcus Aureus Macrodomain (pdb code 8rsl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Staphylococcus Aureus Macrodomain, PDB code: 8rsl:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Staphylococcus Aureus Macrodomain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Staphylococcus Aureus Macrodomain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:21.8 occ:1.00 ND1 A:HIS118 2.1 24.2 1.0 SG A:CYS120 2.3 21.9 1.0 SG A:CYS113 2.3 21.4 1.0 CE1 A:HIS118 3.1 25.7 1.0 CG A:HIS118 3.2 23.2 1.0 CB A:CYS113 3.2 22.6 1.0 CB A:CYS120 3.4 22.3 1.0 CB A:HIS118 3.5 21.1 1.0 NE2 A:HIS118 4.2 24.4 1.0 CD2 A:HIS118 4.3 27.5 1.0 CA A:CYS113 4.5 20.8 1.0 N A:CYS120 4.5 27.1 1.0 CA A:CYS120 4.5 22.1 1.0 CB A:ASN123 4.5 17.5 1.0 O A:HOH469 4.6 29.5 1.0 CB A:GLN115 4.7 25.0 1.0 OE1 A:GLN115 4.8 29.2 1.0 O A:HIS118 4.8 31.0 1.0 CA A:HIS118 4.9 24.4 1.0 C A:HIS118 4.9 28.7 1.0 ND2 A:ASN123 5.0 19.3 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Staphylococcus Aureus Macrodomain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Staphylococcus Aureus Macrodomain within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn301 b:26.2 occ:1.00 ND1 B:HIS118 2.2 25.7 1.0 SG B:CYS120 2.2 23.4 1.0 SG B:CYS113 2.3 26.6 1.0 CE1 B:HIS118 3.1 26.9 1.0 CB B:CYS113 3.1 23.7 1.0 CG B:HIS118 3.2 26.6 1.0 CB B:CYS120 3.4 24.3 1.0 CB B:HIS118 3.5 26.6 1.0 NE2 B:HIS118 4.2 29.9 1.0 CD2 B:HIS118 4.3 31.2 1.0 CA B:CYS113 4.4 24.7 1.0 N B:CYS120 4.4 27.7 1.0 CB B:ASN123 4.4 21.1 1.0 CA B:CYS120 4.5 24.1 1.0 O B:HIS118 4.6 26.4 1.0 CB B:GLN115 4.8 29.3 1.0 CA B:HIS118 4.8 26.7 1.0 C B:HIS118 4.8 29.3 1.0 OE1 B:GLN115 4.8 39.6 1.0 ND2 B:ASN123 4.9 21.8 1.0 N B:ASN123 5.0 20.4 1.0 O B:HOH442 5.0 29.8 1.0

A.Ariza, Q.Liu, N.Cowleson, I.Ahel, D.V.Filippov, J.G.M.Rack. Evolutionary and Molecular Basis of Adp-Ribosylation Reversal By Zinc-Dependent Macrodomains To Be Published.