Zinc in PDB 8r1g: Dimeric Ternary Structure of E6AP-E6-P53

All present enzymatic activity of Dimeric Ternary Structure of E6AP-E6-P53:
2.3.2.26;

The binding sites of Zinc atom in the Dimeric Ternary Structure of E6AP-E6-P53 (pdb code 8r1g). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the Dimeric Ternary Structure of E6AP-E6-P53, PDB code: 8r1g:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6;

Zinc binding site 1 out of 6 in the Dimeric Ternary Structure of E6AP-E6-P53


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Dimeric Ternary Structure of E6AP-E6-P53 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:114.6 occ:1.00 SG B:CYS110 2.3 88.6 1.0 SG B:CYS143 2.3 87.2 1.0 SG B:CYS146 2.3 93.3 1.0 SG B:CYS113 2.3 88.0 1.0 HB2 B:CYS146 3.0 93.3 1.0 HB2 B:CYS110 3.1 88.6 1.0 CB B:CYS110 3.2 88.6 1.0 CB B:CYS146 3.3 93.3 1.0 HB2 B:ASN112 3.3 82.5 1.0 H B:CYS113 3.3 88.0 1.0 HB3 B:CYS110 3.4 88.6 1.0 CB B:CYS113 3.6 88.0 1.0 H B:CYS143 3.6 87.2 1.0 HB3 B:CYS113 3.7 88.0 1.0 N B:CYS113 3.8 88.0 1.0 HB3 B:CYS146 3.9 93.3 1.0 CB B:CYS143 4.0 87.2 1.0 H B:ASN112 4.1 82.5 1.0 HB3 B:CYS143 4.1 87.2 1.0 CA B:CYS113 4.2 88.0 1.0 CB B:ASN112 4.3 82.5 1.0 N B:CYS143 4.4 87.2 1.0 HB2 B:CYS113 4.4 88.0 1.0 N B:CYS146 4.4 93.3 1.0 CA B:CYS146 4.5 93.3 1.0 H B:CYS146 4.5 93.3 1.0 HB3 B:LYS115 4.5 83.4 1.0 HB2 B:CYS143 4.6 87.2 1.0 C B:ASN112 4.6 82.5 1.0 CA B:CYS110 4.6 88.6 1.0 OD1 B:ASN112 4.6 82.5 1.0 CA B:CYS143 4.7 87.2 1.0 N B:ASN112 4.7 82.5 1.0 C B:CYS113 4.7 88.0 1.0 H B:LYS115 4.8 83.4 1.0 CA B:ASN112 4.8 82.5 1.0 HB3 B:ASN112 4.8 82.5 1.0 HA B:CYS110 4.8 88.6 1.0 HA B:CYS146 4.8 93.3 1.0 C B:SER145 4.9 106.0 1.0 HA B:ARG142 4.9 83.4 1.0 H B:GLN114 4.9 83.9 1.0 CG B:ASN112 5.0 82.5 1.0 HE2 B:LYS115 5.0 83.4 1.0

Zinc binding site 2 out of 6 in the Dimeric Ternary Structure of E6AP-E6-P53


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Dimeric Ternary Structure of E6AP-E6-P53 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn202 b:138.4 occ:1.00 SG B:CYS37 2.3 114.5 1.0 SG B:CYS40 2.3 108.2 1.0 SG B:CYS73 2.3 99.2 1.0 SG B:CYS70 2.3 103.6 1.0 HB2 B:CYS73 2.8 99.2 1.0 HB3 B:CYS37 2.9 114.5 1.0 CB B:CYS37 3.0 114.5 1.0 CB B:CYS73 3.1 99.2 1.0 HB2 B:CYS37 3.2 114.5 1.0 H B:CYS40 3.2 108.2 1.0 H B:CYS70 3.4 103.6 1.0 HB3 B:CYS73 3.6 99.2 1.0 CB B:CYS40 3.8 108.2 1.0 HB3 B:CYS40 3.8 108.2 1.0 HB2 B:TYR39 3.8 105.6 1.0 H B:CYS73 3.8 99.2 1.0 CB B:CYS70 3.9 103.6 1.0 HB3 B:CYS70 4.0 103.6 1.0 N B:CYS40 4.0 108.2 1.0 HE2 B:LYS72 4.0 98.8 1.0 HG3 B:LYS72 4.1 98.8 1.0 H B:TYR39 4.2 105.6 1.0 N B:CYS70 4.2 103.6 1.0 HG21 B:VAL69 4.2 103.0 1.0 HD2 B:TYR39 4.3 105.6 1.0 CA B:CYS73 4.4 99.2 1.0 N B:CYS73 4.4 99.2 1.0 HB2 B:CYS40 4.4 108.2 1.0 CA B:CYS37 4.5 114.5 1.0 HB2 B:CYS70 4.5 103.6 1.0 CA B:CYS40 4.5 108.2 1.0 CA B:CYS70 4.6 103.6 1.0 HB3 B:GLN42 4.7 118.0 1.0 HA B:VAL69 4.7 103.0 1.0 HA B:CYS73 4.7 99.2 1.0 CB B:TYR39 4.7 105.6 1.0 C B:CYS37 4.8 114.5 1.0 HG2 B:LYS72 4.8 98.8 1.0 H B:GLN42 4.8 118.0 1.0 HZ3 B:LYS72 4.9 98.8 1.0 HG23 B:VAL69 4.9 103.0 1.0 CG B:LYS72 4.9 98.8 1.0 HA B:CYS37 4.9 114.5 1.0 N B:TYR39 4.9 105.6 1.0 CE B:LYS72 4.9 98.8 1.0 O B:CYS37 5.0 114.5 1.0

Zinc binding site 3 out of 6 in the Dimeric Ternary Structure of E6AP-E6-P53


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Dimeric Ternary Structure of E6AP-E6-P53 within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn401 b:241.6 occ:1.00 ND1 C:HIS179 2.0 189.1 1.0 HB3 C:CYS176 2.2 187.3 1.0 SG C:CYS238 2.3 182.9 1.0 SG C:CYS176 2.3 187.3 1.0 SG C:CYS242 2.3 171.6 1.0 HE1 C:HIS179 2.5 189.1 1.0 CE1 C:HIS179 2.6 189.1 1.0 CB C:CYS176 2.7 187.3 1.0 HB3 C:CYS242 2.7 171.6 1.0 CB C:CYS242 3.0 171.6 1.0 HB2 C:CYS242 3.2 171.6 1.0 H C:CYS176 3.3 187.3 1.0 CG C:HIS179 3.3 189.1 1.0 HB2 C:CYS176 3.4 187.3 1.0 H C:ASN239 3.4 175.5 1.0 HB2 C:HIS179 3.5 189.1 1.0 CA C:CYS176 3.7 187.3 1.0 HA C:CYS238 3.8 182.9 1.0 N C:CYS176 3.8 187.3 1.0 NE2 C:HIS179 3.8 189.1 1.0 CB C:CYS238 3.9 182.9 1.0 CB C:HIS179 4.0 189.1 1.0 H C:HIS179 4.0 189.1 1.0 N C:ASN239 4.1 175.5 1.0 CD2 C:HIS179 4.2 189.1 1.0 O C:CYS176 4.2 187.3 1.0 CA C:CYS238 4.3 182.9 1.0 C C:CYS176 4.3 187.3 1.0 HB3 C:CYS238 4.3 182.9 1.0 CA C:CYS242 4.4 171.6 1.0 HB2 C:CYS238 4.5 182.9 1.0 O C:ASN239 4.5 175.5 1.0 HE2 C:HIS179 4.5 189.1 1.0 HA C:CYS176 4.5 187.3 1.0 HA C:CYS242 4.6 171.6 1.0 HG2 C:ARG175 4.6 180.8 1.0 HB3 C:HIS179 4.6 189.1 1.0 N C:HIS179 4.7 189.1 1.0 C C:CYS238 4.7 182.9 1.0 HB2 C:ASN239 4.7 175.5 1.0 HB3 C:HIS178 4.7 183.1 1.0 HA3 C:GLY245 5.0 177.5 1.0

Zinc binding site 4 out of 6 in the Dimeric Ternary Structure of E6AP-E6-P53


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Dimeric Ternary Structure of E6AP-E6-P53 within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn201 b:81.6 occ:1.00 SG E:CYS110 2.3 66.0 1.0 SG E:CYS113 2.3 66.8 1.0 SG E:CYS143 2.3 67.4 1.0 SG E:CYS146 2.3 72.7 1.0 HB2 E:CYS146 3.0 72.7 1.0 HB2 E:CYS110 3.1 66.0 1.0 CB E:CYS110 3.2 66.0 1.0 CB E:CYS146 3.3 72.7 1.0 HB2 E:ASN112 3.3 66.5 1.0 H E:CYS113 3.3 66.8 1.0 HB3 E:CYS110 3.4 66.0 1.0 H E:CYS143 3.6 67.4 1.0 CB E:CYS113 3.6 66.8 1.0 HB3 E:CYS113 3.7 66.8 1.0 N E:CYS113 3.8 66.8 1.0 HB3 E:CYS146 3.9 72.7 1.0 CB E:CYS143 4.0 67.4 1.0 H E:ASN112 4.1 66.5 1.0 HB3 E:CYS143 4.1 67.4 1.0 CA E:CYS113 4.2 66.8 1.0 CB E:ASN112 4.3 66.5 1.0 N E:CYS143 4.4 67.4 1.0 HB2 E:CYS113 4.4 66.8 1.0 N E:CYS146 4.5 72.7 1.0 CA E:CYS146 4.5 72.7 1.0 H E:CYS146 4.5 72.7 1.0 HB3 E:LYS115 4.5 62.6 1.0 HB2 E:CYS143 4.6 67.4 1.0 C E:ASN112 4.6 66.5 1.0 CA E:CYS110 4.6 66.0 1.0 OD1 E:ASN112 4.6 66.5 1.0 CA E:CYS143 4.7 67.4 1.0 N E:ASN112 4.7 66.5 1.0 H E:LYS115 4.8 62.6 1.0 C E:CYS113 4.8 66.8 1.0 CA E:ASN112 4.8 66.5 1.0 HB3 E:ASN112 4.8 66.5 1.0 HA E:CYS110 4.8 66.0 1.0 HA E:CYS146 4.8 72.7 1.0 C E:SER145 4.9 85.0 1.0 HA E:ARG142 4.9 64.2 1.0 H E:GLN114 4.9 62.0 1.0 CG E:ASN112 5.0 66.5 1.0 HE2 E:LYS115 5.0 62.6 1.0

Zinc binding site 5 out of 6 in the Dimeric Ternary Structure of E6AP-E6-P53


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Dimeric Ternary Structure of E6AP-E6-P53 within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn202 b:111.3 occ:1.00 SG E:CYS37 2.3 91.5 1.0 SG E:CYS40 2.3 85.5 1.0 SG E:CYS73 2.3 79.7 1.0 SG E:CYS70 2.3 82.7 1.0 HB2 E:CYS73 2.8 79.7 1.0 HB3 E:CYS37 2.9 91.5 1.0 CB E:CYS37 3.0 91.5 1.0 CB E:CYS73 3.1 79.7 1.0 HB2 E:CYS37 3.2 91.5 1.0 H E:CYS40 3.2 85.5 1.0 H E:CYS70 3.4 82.7 1.0 HB3 E:CYS73 3.6 79.7 1.0 CB E:CYS40 3.7 85.5 1.0 HB3 E:CYS40 3.8 85.5 1.0 HB2 E:TYR39 3.8 86.1 1.0 H E:CYS73 3.8 79.7 1.0 CB E:CYS70 3.9 82.7 1.0 HB3 E:CYS70 4.0 82.7 1.0 N E:CYS40 4.0 85.5 1.0 HE2 E:LYS72 4.0 82.4 1.0 HG3 E:LYS72 4.1 82.4 1.0 H E:TYR39 4.2 86.1 1.0 N E:CYS70 4.2 82.7 1.0 HG21 E:VAL69 4.2 80.7 1.0 HD2 E:TYR39 4.3 86.1 1.0 CA E:CYS73 4.3 79.7 1.0 N E:CYS73 4.4 79.7 1.0 HB2 E:CYS40 4.4 85.5 1.0 CA E:CYS37 4.5 91.5 1.0 CA E:CYS40 4.5 85.5 1.0 HB2 E:CYS70 4.5 82.7 1.0 CA E:CYS70 4.6 82.7 1.0 HB3 E:GLN42 4.7 93.8 1.0 HA E:VAL69 4.7 80.7 1.0 HA E:CYS73 4.7 79.7 1.0 CB E:TYR39 4.7 86.1 1.0 C E:CYS37 4.8 91.5 1.0 HG2 E:LYS72 4.8 82.4 1.0 H E:GLN42 4.8 93.8 1.0 HZ3 E:LYS72 4.9 82.4 1.0 CG E:LYS72 4.9 82.4 1.0 HG23 E:VAL69 4.9 80.7 1.0 HA E:CYS37 4.9 91.5 1.0 N E:TYR39 4.9 86.1 1.0 CE E:LYS72 4.9 82.4 1.0 O E:CYS37 5.0 91.5 1.0

Zinc binding site 6 out of 6 in the Dimeric Ternary Structure of E6AP-E6-P53


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Dimeric Ternary Structure of E6AP-E6-P53 within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn401 b:257.0 occ:1.00 ND1 F:HIS179 2.0 183.2 1.0 HB3 F:CYS176 2.2 183.5 1.0 SG F:CYS238 2.3 173.4 1.0 SG F:CYS176 2.3 183.5 1.0 SG F:CYS242 2.3 170.9 1.0 HE1 F:HIS179 2.5 183.2 1.0 CE1 F:HIS179 2.6 183.2 1.0 CB F:CYS176 2.7 183.5 1.0 HB3 F:CYS242 2.7 170.9 1.0 CB F:CYS242 3.0 170.9 1.0 HB2 F:CYS242 3.2 170.9 1.0 H F:CYS176 3.3 183.5 1.0 CG F:HIS179 3.3 183.2 1.0 H F:ASN239 3.4 167.4 1.0 HB2 F:CYS176 3.4 183.5 1.0 HB2 F:HIS179 3.5 183.2 1.0 CA F:CYS176 3.7 183.5 1.0 HA F:CYS238 3.8 173.4 1.0 N F:CYS176 3.8 183.5 1.0 NE2 F:HIS179 3.8 183.2 1.0 CB F:CYS238 3.9 173.4 1.0 CB F:HIS179 4.0 183.2 1.0 H F:HIS179 4.0 183.2 1.0 N F:ASN239 4.1 167.4 1.0 O F:CYS176 4.2 183.5 1.0 CD2 F:HIS179 4.2 183.2 1.0 CA F:CYS238 4.3 173.4 1.0 C F:CYS176 4.3 183.5 1.0 HB3 F:CYS238 4.3 173.4 1.0 CA F:CYS242 4.4 170.9 1.0 HB2 F:CYS238 4.5 173.4 1.0 O F:ASN239 4.5 167.4 1.0 HE2 F:HIS179 4.5 183.2 1.0 HA F:CYS176 4.5 183.5 1.0 HA F:CYS242 4.6 170.9 1.0 HG2 F:ARG175 4.6 177.3 1.0 HB3 F:HIS179 4.6 183.2 1.0 N F:HIS179 4.7 183.2 1.0 C F:CYS238 4.7 173.4 1.0 HB2 F:ASN239 4.7 167.4 1.0 HB3 F:HIS178 4.7 182.8 1.0 HA3 F:GLY245 5.0 172.3 1.0

C.R.Sandate, D.Chakraborty, L.Kater, G.Kempf, N.H.Thomae. Monomeric E6AP-E6-P53 Ternary Complex To Be Published.