Zinc in PDB 8pth: Tilapia Lake Virus Polymerase in Vrna Pre-Initiation State Mode B (Open Core | Partial Replicase Conformation)

The binding sites of Zinc atom in the Tilapia Lake Virus Polymerase in Vrna Pre-Initiation State Mode B (Open Core | Partial Replicase Conformation) (pdb code 8pth). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Tilapia Lake Virus Polymerase in Vrna Pre-Initiation State Mode B (Open Core | Partial Replicase Conformation), PDB code: 8pth:

Zinc binding site 1 out of 1 in the Tilapia Lake Virus Polymerase in Vrna Pre-Initiation State Mode B (Open Core | Partial Replicase Conformation)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Tilapia Lake Virus Polymerase in Vrna Pre-Initiation State Mode B (Open Core | Partial Replicase Conformation) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:91.9 occ:1.00 NE2 A:HIS296 2.0 33.1 1.0 ND1 A:HIS284 2.0 48.0 1.0 SG A:CYS161 2.3 43.1 1.0 SG A:CYS282 2.3 58.3 1.0 CE1 A:HIS284 2.9 49.3 1.0 HE1 A:HIS284 3.0 48.1 1.0 CD2 A:HIS296 3.0 30.9 1.0 H A:HIS284 3.0 49.3 1.0 CE1 A:HIS296 3.1 30.2 1.0 HB2 A:HIS284 3.1 47.9 1.0 HD2 A:HIS296 3.1 37.6 1.0 HB2 A:CYS282 3.1 51.0 1.0 CG A:HIS284 3.2 39.2 1.0 HE1 A:HIS296 3.3 37.3 1.0 CB A:CYS282 3.4 50.3 1.0 CB A:CYS161 3.4 40.5 1.0 HB2 A:CYS161 3.4 41.0 1.0 HB3 A:CYS161 3.5 40.8 1.0 CB A:HIS284 3.6 43.5 1.0 HB3 A:CYS282 3.8 50.7 1.0 N A:HIS284 3.9 52.7 1.0 HA A:LYS163 3.9 37.9 1.0 HB1 A:ALA294 4.0 43.2 1.0 H A:LYS163 4.0 38.2 1.0 H A:GLU283 4.0 58.2 1.0 NE2 A:HIS284 4.0 50.2 1.0 CG A:HIS296 4.1 32.4 1.0 ND1 A:HIS296 4.1 36.7 1.0 CD2 A:HIS284 4.2 44.5 1.0 CA A:HIS284 4.3 45.1 1.0 N A:GLU283 4.4 57.0 1.0 HB3 A:HIS284 4.4 48.4 1.0 HG2 A:LYS163 4.5 38.0 1.0 HB3 A:GLU283 4.6 58.0 1.0 HD3 A:LYS163 4.6 37.3 1.0 CA A:CYS282 4.6 49.6 1.0 N A:LYS163 4.7 33.9 1.0 CA A:LYS163 4.7 34.0 1.0 C A:CYS282 4.7 48.9 1.0 HE2 A:HIS284 4.8 48.4 1.0 CA A:CYS161 4.8 36.9 1.0 CB A:ALA294 4.9 36.8 1.0 HD1 A:HIS296 4.9 38.3 1.0 C A:GLU283 4.9 57.9 1.0 C A:HIS284 5.0 43.5 1.0

B.Arragain, M.Pelosse, A.Thompson, S.Cusack. Structural and Functional Analysis of the Minimal Orthomyxovirus-Like Polymerase of Tilapia Lake Virus From the Highly Diverged Amnoonviridae Family. Nat Commun V. 14 8145 2023.
ISSN: ESSN 2041-1723
PubMed: 38066000
DOI: 10.1038/S41467-023-44044-X