Zinc in PDB 8p9b: Crystal Structure of MNK2-D228G in Complex with Tinodasertib

All present enzymatic activity of Crystal Structure of MNK2-D228G in Complex with Tinodasertib:
2.7.11.1;

The structure of Crystal Structure of MNK2-D228G in Complex with Tinodasertib, PDB code: 8p9b was solved by A.P.Turnbull, V.Sabin, C.Bell, M.Watson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.01 / 2.59
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	105.91, 105.91, 71.5, 90, 90, 120
R / Rfree (%)	20.8 / 26.4

The binding sites of Zinc atom in the Crystal Structure of MNK2-D228G in Complex with Tinodasertib (pdb code 8p9b). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of MNK2-D228G in Complex with Tinodasertib, PDB code: 8p9b:

Zinc binding site 1 out of 1 in the Crystal Structure of MNK2-D228G in Complex with Tinodasertib


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of MNK2-D228G in Complex with Tinodasertib within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:294.6 occ:1.00 SG A:CYS299 2.4 225.0 1.0 SG A:CYS314 2.4 214.3 1.0 SG A:CYS311 2.4 252.1 1.0 CB A:CYS299 3.4 195.3 1.0 CB A:CYS314 3.5 184.0 1.0 N A:CYS314 3.6 187.8 1.0 CB A:CYS311 3.6 234.9 1.0 CA A:CYS314 3.9 175.7 1.0 C A:ALA313 4.3 187.6 1.0 CA A:CYS299 4.4 185.1 1.0 CA A:CYS311 4.4 218.0 1.0 N A:CYS311 4.4 208.4 1.0 CB A:ALA313 4.4 185.4 1.0 C A:CYS311 4.6 212.9 1.0 N A:ALA313 4.7 199.8 1.0 CA A:ALA313 4.7 189.0 1.0 O A:CYS311 4.8 192.2 1.0

V.Sabin, A.P.Turnbull, C.Bell, M.Watson. Crystal Structure of MNK2-D228G in Complex with Tinodasertib To Be Published.