Zinc in PDB 8p62: S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation
Enzymatic activity of S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation
All present enzymatic activity of S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation:
2.7.7.7;
3.6.4.12;
Other elements in 8p62:
The structure of S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation
(pdb code 8p62). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 7 binding sites of Zinc where determined in the
S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation, PDB code: 8p62:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
Zinc binding site 1 out
of 7 in 8p62
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Zinc Binding Sites List in 8p62
Zinc binding site 1 out
of 7 in the S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
2:Zn902
b:303.6
occ:1.00
|
CB
|
2:CYS367
|
1.8
|
297.8
|
1.0
|
SG
|
2:CYS367
|
2.3
|
297.8
|
1.0
|
SG
|
2:CYS344
|
2.3
|
270.0
|
1.0
|
CB
|
2:CYS344
|
2.8
|
270.0
|
1.0
|
CA
|
2:CYS367
|
3.1
|
297.8
|
1.0
|
OG
|
2:SER346
|
3.4
|
247.8
|
1.0
|
N
|
2:CYS367
|
3.5
|
297.8
|
1.0
|
OD1
|
2:ASN366
|
3.8
|
296.9
|
1.0
|
NZ
|
2:LYS343
|
4.1
|
273.0
|
1.0
|
C
|
2:CYS367
|
4.3
|
297.8
|
1.0
|
CA
|
2:CYS344
|
4.3
|
270.0
|
1.0
|
CB
|
2:SER346
|
4.7
|
247.8
|
1.0
|
O
|
2:CYS344
|
4.8
|
270.0
|
1.0
|
C
|
2:ASN366
|
4.8
|
296.9
|
1.0
|
O
|
2:CYS364
|
4.9
|
285.1
|
1.0
|
O
|
2:CYS367
|
4.9
|
297.8
|
1.0
|
C
|
2:CYS344
|
4.9
|
270.0
|
1.0
|
|
Zinc binding site 2 out
of 7 in 8p62
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Zinc Binding Sites List in 8p62
Zinc binding site 2 out
of 7 in the S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
4:Zn1002
b:201.1
occ:1.00
|
SG
|
4:CYS349
|
2.3
|
152.2
|
1.0
|
SG
|
4:CYS376
|
2.3
|
175.3
|
1.0
|
SG
|
4:CYS352
|
2.3
|
157.3
|
1.0
|
CB
|
4:CYS352
|
3.4
|
157.3
|
1.0
|
CB
|
4:CYS349
|
3.6
|
152.2
|
1.0
|
SG
|
4:CYS371
|
3.6
|
172.5
|
1.0
|
CB
|
4:CYS376
|
3.7
|
175.3
|
1.0
|
CB
|
4:CYS371
|
4.0
|
172.5
|
1.0
|
N
|
4:CYS352
|
4.1
|
157.3
|
1.0
|
CA
|
4:CYS352
|
4.4
|
157.3
|
1.0
|
OG
|
4:SER381
|
4.4
|
157.8
|
1.0
|
CB
|
4:ARG373
|
4.6
|
170.5
|
1.0
|
O
|
4:CYS349
|
4.8
|
152.2
|
1.0
|
CD
|
4:ARG373
|
4.8
|
170.5
|
1.0
|
O
|
4:ARG373
|
4.9
|
170.5
|
1.0
|
CA
|
4:CYS349
|
4.9
|
152.2
|
1.0
|
CB
|
4:VAL351
|
4.9
|
154.5
|
1.0
|
CA
|
4:CYS376
|
5.0
|
175.3
|
1.0
|
|
Zinc binding site 3 out
of 7 in 8p62
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Zinc Binding Sites List in 8p62
Zinc binding site 3 out
of 7 in the S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
5:Zn1702
b:195.9
occ:1.00
|
CB
|
5:CYS186
|
2.2
|
144.2
|
1.0
|
SG
|
5:CYS211
|
2.3
|
171.3
|
1.0
|
SG
|
5:CYS186
|
2.3
|
144.2
|
1.0
|
CB
|
5:CYS211
|
3.6
|
171.3
|
1.0
|
CA
|
5:CYS186
|
3.7
|
144.2
|
1.0
|
SG
|
5:CYS236
|
4.0
|
167.4
|
1.0
|
ND1
|
5:HIS188
|
4.1
|
139.0
|
1.0
|
O
|
5:LEU212
|
4.1
|
164.2
|
1.0
|
CE1
|
5:HIS188
|
4.4
|
139.0
|
1.0
|
N
|
5:CYS186
|
4.4
|
144.2
|
1.0
|
C
|
5:CYS186
|
4.5
|
144.2
|
1.0
|
N
|
5:LEU212
|
4.7
|
164.2
|
1.0
|
N
|
5:LYS234
|
4.9
|
162.3
|
1.0
|
CA
|
5:CYS211
|
4.9
|
171.3
|
1.0
|
C
|
5:LEU212
|
5.0
|
164.2
|
1.0
|
|
Zinc binding site 4 out
of 7 in 8p62
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Zinc Binding Sites List in 8p62
Zinc binding site 4 out
of 7 in the S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
6:Zn1102
b:178.2
occ:1.00
|
SG
|
6:CYS333
|
2.3
|
132.0
|
1.0
|
SG
|
6:CYS311
|
2.3
|
140.5
|
1.0
|
SG
|
6:CYS338
|
2.3
|
147.7
|
1.0
|
SG
|
6:CYS314
|
2.3
|
139.9
|
1.0
|
CB
|
6:CYS333
|
3.0
|
132.0
|
1.0
|
CB
|
6:CYS338
|
3.1
|
147.7
|
1.0
|
CB
|
6:CYS311
|
3.2
|
140.5
|
1.0
|
SD
|
6:MET313
|
3.6
|
144.6
|
1.0
|
CB
|
6:CYS314
|
3.7
|
139.9
|
1.0
|
CB
|
6:ALA316
|
4.5
|
131.6
|
1.0
|
O
|
6:CYS311
|
4.5
|
140.5
|
1.0
|
CA
|
6:CYS333
|
4.5
|
132.0
|
1.0
|
CA
|
6:CYS311
|
4.5
|
140.5
|
1.0
|
CA
|
6:CYS338
|
4.5
|
147.7
|
1.0
|
CE
|
6:MET313
|
4.6
|
144.6
|
1.0
|
CB
|
6:ASN335
|
4.6
|
137.8
|
1.0
|
N
|
6:ASN340
|
4.7
|
139.3
|
1.0
|
N
|
6:CYS314
|
4.7
|
139.9
|
1.0
|
CA
|
6:CYS314
|
4.8
|
139.9
|
1.0
|
C
|
6:CYS311
|
4.8
|
140.5
|
1.0
|
CA
|
6:ASN340
|
4.8
|
139.3
|
1.0
|
CG
|
6:MET313
|
4.9
|
144.6
|
1.0
|
CB
|
6:ASN340
|
5.0
|
139.3
|
1.0
|
C
|
6:CYS338
|
5.0
|
147.7
|
1.0
|
|
Zinc binding site 5 out
of 7 in 8p62
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Zinc Binding Sites List in 8p62
Zinc binding site 5 out
of 7 in the S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
7:Zn903
b:198.6
occ:1.00
|
O
|
7:LYS295
|
2.1
|
211.1
|
1.0
|
SG
|
7:CYS289
|
2.3
|
214.2
|
1.0
|
SG
|
7:CYS265
|
2.3
|
183.2
|
1.0
|
O
|
7:CYS262
|
2.5
|
182.2
|
1.0
|
CB
|
7:CYS265
|
2.9
|
183.2
|
1.0
|
C
|
7:LYS295
|
3.3
|
211.1
|
1.0
|
SG
|
7:CYS262
|
3.5
|
182.2
|
1.0
|
C
|
7:CYS262
|
3.7
|
182.2
|
1.0
|
O
|
7:GLY296
|
3.8
|
194.8
|
1.0
|
CB
|
7:CYS289
|
4.0
|
214.2
|
1.0
|
CA
|
7:GLY296
|
4.1
|
194.8
|
1.0
|
O
|
7:ASP263
|
4.1
|
178.9
|
1.0
|
N
|
7:GLY296
|
4.2
|
194.8
|
1.0
|
CB
|
7:LYS295
|
4.2
|
211.1
|
1.0
|
CG
|
7:LYS295
|
4.2
|
211.1
|
1.0
|
CB
|
7:ASP263
|
4.3
|
178.9
|
1.0
|
CA
|
7:CYS265
|
4.3
|
183.2
|
1.0
|
C
|
7:GLY296
|
4.3
|
194.8
|
1.0
|
CA
|
7:LYS295
|
4.3
|
211.1
|
1.0
|
CA
|
7:CYS262
|
4.5
|
182.2
|
1.0
|
CB
|
7:CYS262
|
4.5
|
182.2
|
1.0
|
N
|
7:CYS265
|
4.6
|
183.2
|
1.0
|
SG
|
7:CYS284
|
4.6
|
190.6
|
1.0
|
C
|
7:ASP263
|
4.6
|
178.9
|
1.0
|
N
|
7:ASP263
|
4.6
|
178.9
|
1.0
|
CA
|
7:ASP263
|
4.7
|
178.9
|
1.0
|
CA
|
7:CYS289
|
4.9
|
214.2
|
1.0
|
|
Zinc binding site 6 out
of 7 in 8p62
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Zinc Binding Sites List in 8p62
Zinc binding site 6 out
of 7 in the S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Zn4001
b:172.5
occ:1.00
|
SG
|
G:CYS2133
|
2.3
|
138.3
|
1.0
|
SG
|
G:CYS2111
|
2.3
|
141.3
|
1.0
|
SG
|
G:CYS2108
|
2.3
|
139.3
|
1.0
|
SG
|
G:CYS2130
|
2.3
|
141.1
|
1.0
|
CB
|
G:CYS2130
|
2.9
|
141.1
|
1.0
|
CB
|
G:CYS2108
|
3.5
|
139.3
|
1.0
|
CB
|
G:CYS2133
|
3.5
|
138.3
|
1.0
|
CB
|
G:CYS2111
|
3.6
|
141.3
|
1.0
|
N
|
G:CYS2133
|
4.0
|
138.3
|
1.0
|
CA
|
G:CYS2133
|
4.2
|
138.3
|
1.0
|
N
|
G:CYS2111
|
4.3
|
141.3
|
1.0
|
O
|
G:CYS2133
|
4.3
|
138.3
|
1.0
|
CA
|
G:CYS2130
|
4.4
|
141.1
|
1.0
|
CB
|
G:TYR2110
|
4.5
|
146.3
|
1.0
|
CA
|
G:CYS2111
|
4.6
|
141.3
|
1.0
|
C
|
G:CYS2133
|
4.6
|
138.3
|
1.0
|
C
|
G:TYR2110
|
4.7
|
146.3
|
1.0
|
CA
|
G:CYS2108
|
4.8
|
139.3
|
1.0
|
CB
|
G:PHE2113
|
4.9
|
127.5
|
1.0
|
CD2
|
G:TYR2110
|
5.0
|
146.3
|
1.0
|
|
Zinc binding site 7 out
of 7 in 8p62
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Zinc Binding Sites List in 8p62
Zinc binding site 7 out
of 7 in the S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of S. Cerevisiae Ssdna-Scmge After Dna Replication Initiation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Zn4002
b:130.6
occ:1.00
|
SG
|
G:CYS2167
|
2.3
|
109.4
|
1.0
|
SG
|
G:CYS2179
|
2.3
|
105.0
|
1.0
|
SG
|
G:CYS2164
|
2.3
|
99.9
|
1.0
|
CB
|
G:CYS2179
|
2.9
|
105.0
|
1.0
|
CB
|
G:CYS2164
|
3.3
|
99.9
|
1.0
|
O
|
G:ALA2182
|
3.4
|
109.4
|
1.0
|
NZ
|
G:LYS2169
|
3.7
|
101.8
|
1.0
|
CB
|
G:CYS2167
|
3.8
|
109.4
|
1.0
|
N
|
G:CYS2167
|
4.0
|
109.4
|
1.0
|
CB
|
G:CYS2181
|
4.1
|
115.7
|
1.0
|
O
|
G:CYS2167
|
4.3
|
109.4
|
1.0
|
CA
|
G:CYS2179
|
4.4
|
105.0
|
1.0
|
CA
|
G:CYS2167
|
4.4
|
109.4
|
1.0
|
C
|
G:ALA2182
|
4.5
|
109.4
|
1.0
|
C
|
G:CYS2181
|
4.6
|
115.7
|
1.0
|
N
|
G:CYS2181
|
4.7
|
115.7
|
1.0
|
C
|
G:CYS2167
|
4.7
|
109.4
|
1.0
|
CA
|
G:CYS2181
|
4.7
|
115.7
|
1.0
|
O
|
G:CYS2181
|
4.7
|
115.7
|
1.0
|
CA
|
G:CYS2164
|
4.8
|
99.9
|
1.0
|
SG
|
G:CYS2181
|
4.9
|
115.7
|
1.0
|
N
|
G:ARG2166
|
4.9
|
101.9
|
1.0
|
N
|
G:ALA2182
|
4.9
|
109.4
|
1.0
|
|
Reference:
S.S.Henrikus,
M.H.Gross,
O.Willhoft,
T.Puhringer,
J.S.Lewis,
A.W.Mcclure,
J.F.Greiwe,
G.Palm,
A.Nans,
J.F.X.Diffley,
A.Costa.
Unwinding of A Eukaryotic Origin of Replication Visualized By Cryo-Em. Nat.Struct.Mol.Biol. 2024.
ISSN: ESSN 1545-9985
PubMed: 38760633
DOI: 10.1038/S41594-024-01280-Z
Page generated: Thu Oct 31 09:06:38 2024
|