Zinc in PDB 8je2: Cryo-Em Structure of Neddylated CUL2-RBX1-Elobc-FEM1B Complexed with FNIP1-Flcn

The binding sites of Zinc atom in the Cryo-Em Structure of Neddylated CUL2-RBX1-Elobc-FEM1B Complexed with FNIP1-Flcn (pdb code 8je2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Neddylated CUL2-RBX1-Elobc-FEM1B Complexed with FNIP1-Flcn, PDB code: 8je2:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Neddylated CUL2-RBX1-Elobc-FEM1B Complexed with FNIP1-Flcn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Neddylated CUL2-RBX1-Elobc-FEM1B Complexed with FNIP1-Flcn within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn701 b:180.6 occ:1.00 NE2 D:HIS627 1.9 133.2 1.0 SG D:CYS599 2.3 126.9 1.0 CB D:CYS599 2.3 126.9 1.0 CA D:CYS599 2.6 150.5 1.0 NE2 D:HIS565 2.6 127.8 1.0 OD1 D:ASP567 2.8 129.7 1.0 CE1 D:HIS627 2.8 133.2 1.0 CD2 D:HIS627 3.0 133.2 1.0 OD2 D:ASP567 3.1 129.7 1.0 CG D:ASP567 3.3 129.7 1.0 N D:CYS599 3.4 150.5 1.0 CE1 D:HIS565 3.5 127.8 1.0 CD2 D:HIS565 3.5 127.8 1.0 CZ D:PHE623 3.7 124.6 1.0 C D:CYS599 3.8 150.5 1.0 ND1 D:HIS627 3.9 133.2 1.0 CG D:HIS627 4.0 133.2 1.0 CE1 D:PHE623 4.1 124.6 1.0 O D:CYS599 4.1 150.5 1.0 C D:LYS598 4.2 150.5 1.0 O D:LYS598 4.5 150.5 1.0 ND1 D:HIS565 4.6 127.8 1.0 CG D:HIS565 4.6 127.8 1.0 CE2 D:PHE623 4.7 124.6 1.0 CB D:ASP567 4.8 129.7 1.0 N D:LEU600 4.9 150.5 1.0 NH2 D:ARG603 4.9 118.0 1.0

Z.Dai, L.Liang, W.Wang, P.Zuo, S.Yu, Y.Liu, X.Zhao, Y.Lu, Y.Jin, F.Zhang, D.Ding, W.Deng, Y.Yin. Structural Insights Into the Ubiquitylation Strategy of the Oligomeric CRL2 FEM1B E3 Ubiquitin Ligase. Embo J. 2024.
ISSN: ESSN 1460-2075
PubMed: 38360992
DOI: 10.1038/S44318-024-00047-Y