Zinc in PDB 8iq1: Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State
Enzymatic activity of Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State
All present enzymatic activity of Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State:
1.15.1.1;
Protein crystallography data
The structure of Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State, PDB code: 8iq1
was solved by
J.H.Zhou,
W.X.Huang,
R.X.Cheng,
P.J.Zhang,
Y.C.Zhu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
38.28 /
1.80
|
Space group
|
P 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
46.126,
69.961,
91.345,
98.69,
94.83,
103.31
|
R / Rfree (%)
|
18.4 /
21.7
|
Other elements in 8iq1:
The structure of Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State
(pdb code 8iq1). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the
Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State, PDB code: 8iq1:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Zinc binding site 1 out
of 8 in 8iq1
Go back to
Zinc Binding Sites List in 8iq1
Zinc binding site 1 out
of 8 in the Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn202
b:15.7
occ:1.00
|
ND1
|
A:HIS61
|
2.0
|
17.4
|
1.0
|
OD1
|
A:ASP81
|
2.0
|
18.6
|
1.0
|
ND1
|
A:HIS69
|
2.1
|
16.5
|
1.0
|
ND1
|
A:HIS78
|
2.1
|
14.3
|
1.0
|
CG
|
A:ASP81
|
2.8
|
14.1
|
1.0
|
CE1
|
A:HIS61
|
2.9
|
18.4
|
1.0
|
CE1
|
A:HIS69
|
2.9
|
18.3
|
1.0
|
CE1
|
A:HIS78
|
3.0
|
15.6
|
1.0
|
CG
|
A:HIS61
|
3.0
|
15.1
|
1.0
|
OD2
|
A:ASP81
|
3.0
|
14.2
|
1.0
|
CG
|
A:HIS78
|
3.2
|
14.2
|
1.0
|
CG
|
A:HIS69
|
3.2
|
17.7
|
1.0
|
CB
|
A:HIS61
|
3.4
|
14.2
|
1.0
|
CB
|
A:HIS78
|
3.6
|
14.3
|
1.0
|
CB
|
A:HIS69
|
3.7
|
15.6
|
1.0
|
O
|
A:LYS134
|
3.9
|
19.5
|
1.0
|
CA
|
A:HIS69
|
4.0
|
15.9
|
1.0
|
NE2
|
A:HIS61
|
4.0
|
17.4
|
1.0
|
NE2
|
A:HIS78
|
4.1
|
14.6
|
1.0
|
CD2
|
A:HIS61
|
4.1
|
15.9
|
1.0
|
NE2
|
A:HIS69
|
4.1
|
19.4
|
1.0
|
CD2
|
A:HIS78
|
4.2
|
13.6
|
1.0
|
CB
|
A:ASP81
|
4.2
|
14.0
|
1.0
|
CD2
|
A:HIS69
|
4.3
|
18.2
|
1.0
|
CA
|
A:ASP81
|
4.7
|
13.8
|
1.0
|
O
|
A:HOH364
|
4.7
|
20.8
|
1.0
|
N
|
A:GLY70
|
4.8
|
17.4
|
1.0
|
N
|
A:HIS78
|
4.8
|
13.3
|
1.0
|
CA
|
A:HIS78
|
4.8
|
13.0
|
1.0
|
C
|
A:LYS134
|
4.9
|
20.3
|
1.0
|
CA
|
A:HIS61
|
4.9
|
14.0
|
1.0
|
CD2
|
A:HIS44
|
4.9
|
15.3
|
1.0
|
C
|
A:HIS69
|
5.0
|
20.2
|
1.0
|
N
|
A:ASP81
|
5.0
|
13.3
|
1.0
|
|
Zinc binding site 2 out
of 8 in 8iq1
Go back to
Zinc Binding Sites List in 8iq1
Zinc binding site 2 out
of 8 in the Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn202
b:18.6
occ:1.00
|
ND1
|
B:HIS78
|
1.9
|
19.5
|
1.0
|
OD1
|
B:ASP81
|
2.0
|
19.7
|
1.0
|
ND1
|
B:HIS69
|
2.0
|
21.7
|
1.0
|
ND1
|
B:HIS61
|
2.2
|
22.4
|
1.0
|
CE1
|
B:HIS78
|
2.7
|
20.1
|
1.0
|
CG
|
B:ASP81
|
2.8
|
18.0
|
1.0
|
CE1
|
B:HIS69
|
2.9
|
21.5
|
1.0
|
OD2
|
B:ASP81
|
2.9
|
19.5
|
1.0
|
CG
|
B:HIS78
|
3.0
|
19.0
|
1.0
|
CG
|
B:HIS69
|
3.1
|
22.6
|
1.0
|
CG
|
B:HIS61
|
3.2
|
22.6
|
1.0
|
CE1
|
B:HIS61
|
3.2
|
24.8
|
1.0
|
CB
|
B:HIS61
|
3.4
|
17.4
|
1.0
|
CB
|
B:HIS78
|
3.5
|
16.6
|
1.0
|
CB
|
B:HIS69
|
3.6
|
23.8
|
1.0
|
NE2
|
B:HIS78
|
3.9
|
21.2
|
1.0
|
O
|
B:LYS134
|
3.9
|
28.8
|
1.0
|
CA
|
B:HIS69
|
3.9
|
19.9
|
1.0
|
CD2
|
B:HIS78
|
4.0
|
19.5
|
1.0
|
NE2
|
B:HIS69
|
4.1
|
22.8
|
1.0
|
CB
|
B:ASP81
|
4.2
|
19.7
|
1.0
|
CD2
|
B:HIS69
|
4.2
|
24.1
|
1.0
|
NE2
|
B:HIS61
|
4.3
|
24.3
|
1.0
|
CD2
|
B:HIS61
|
4.3
|
24.6
|
1.0
|
N
|
B:HIS78
|
4.7
|
16.8
|
1.0
|
CA
|
B:ASP81
|
4.7
|
17.2
|
1.0
|
N
|
B:GLY70
|
4.7
|
19.8
|
1.0
|
CA
|
B:HIS78
|
4.7
|
16.2
|
1.0
|
C
|
B:HIS69
|
4.9
|
22.2
|
1.0
|
N
|
B:ASP81
|
4.9
|
15.5
|
1.0
|
C
|
B:LYS134
|
4.9
|
30.4
|
1.0
|
O
|
B:HOH378
|
4.9
|
33.1
|
1.0
|
N
|
B:HIS69
|
4.9
|
21.2
|
1.0
|
CA
|
B:HIS61
|
5.0
|
17.6
|
1.0
|
|
Zinc binding site 3 out
of 8 in 8iq1
Go back to
Zinc Binding Sites List in 8iq1
Zinc binding site 3 out
of 8 in the Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn202
b:19.7
occ:1.00
|
OD1
|
C:ASP81
|
1.9
|
18.1
|
1.0
|
ND1
|
C:HIS78
|
1.9
|
18.8
|
1.0
|
ND1
|
C:HIS61
|
2.0
|
20.5
|
1.0
|
ND1
|
C:HIS69
|
2.1
|
23.2
|
1.0
|
CG
|
C:ASP81
|
2.7
|
19.2
|
1.0
|
CE1
|
C:HIS78
|
2.8
|
18.7
|
1.0
|
OD2
|
C:ASP81
|
2.9
|
19.0
|
1.0
|
CE1
|
C:HIS69
|
3.0
|
22.4
|
1.0
|
CE1
|
C:HIS61
|
3.0
|
20.6
|
1.0
|
CG
|
C:HIS78
|
3.0
|
17.3
|
1.0
|
CG
|
C:HIS61
|
3.0
|
20.0
|
1.0
|
CG
|
C:HIS69
|
3.2
|
23.6
|
1.0
|
CB
|
C:HIS61
|
3.4
|
15.3
|
1.0
|
CB
|
C:HIS78
|
3.5
|
16.6
|
1.0
|
CB
|
C:HIS69
|
3.7
|
22.2
|
1.0
|
NE2
|
C:HIS78
|
3.9
|
16.9
|
1.0
|
CA
|
C:HIS69
|
4.0
|
21.8
|
1.0
|
O
|
C:LYS134
|
4.0
|
23.6
|
1.0
|
CD2
|
C:HIS78
|
4.1
|
17.1
|
1.0
|
NE2
|
C:HIS61
|
4.1
|
21.8
|
1.0
|
CB
|
C:ASP81
|
4.1
|
17.5
|
1.0
|
NE2
|
C:HIS69
|
4.1
|
24.7
|
1.0
|
CD2
|
C:HIS61
|
4.2
|
19.4
|
1.0
|
CD2
|
C:HIS69
|
4.3
|
24.0
|
1.0
|
CA
|
C:ASP81
|
4.7
|
18.6
|
1.0
|
N
|
C:HIS78
|
4.7
|
18.5
|
1.0
|
N
|
C:GLY70
|
4.7
|
21.4
|
1.0
|
CA
|
C:HIS78
|
4.7
|
17.7
|
1.0
|
O
|
C:HOH378
|
4.8
|
24.1
|
1.0
|
C
|
C:HIS69
|
4.9
|
24.0
|
1.0
|
CA
|
C:HIS61
|
4.9
|
15.0
|
1.0
|
N
|
C:ASP81
|
4.9
|
19.5
|
1.0
|
|
Zinc binding site 4 out
of 8 in 8iq1
Go back to
Zinc Binding Sites List in 8iq1
Zinc binding site 4 out
of 8 in the Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn202
b:16.4
occ:1.00
|
OD1
|
D:ASP81
|
2.0
|
13.4
|
1.0
|
ND1
|
D:HIS69
|
2.0
|
16.9
|
1.0
|
ND1
|
D:HIS78
|
2.0
|
16.4
|
1.0
|
ND1
|
D:HIS61
|
2.1
|
14.7
|
1.0
|
CG
|
D:ASP81
|
2.7
|
14.2
|
1.0
|
CE1
|
D:HIS78
|
2.8
|
18.5
|
1.0
|
CE1
|
D:HIS69
|
2.8
|
16.7
|
1.0
|
OD2
|
D:ASP81
|
2.9
|
17.1
|
1.0
|
CE1
|
D:HIS61
|
3.1
|
15.2
|
1.0
|
CG
|
D:HIS61
|
3.1
|
16.0
|
1.0
|
CG
|
D:HIS78
|
3.1
|
17.4
|
1.0
|
CG
|
D:HIS69
|
3.1
|
18.0
|
1.0
|
CB
|
D:HIS61
|
3.4
|
14.6
|
1.0
|
CB
|
D:HIS69
|
3.6
|
18.9
|
1.0
|
CB
|
D:HIS78
|
3.7
|
15.9
|
1.0
|
NE2
|
D:HIS78
|
3.9
|
17.4
|
1.0
|
CA
|
D:HIS69
|
4.0
|
20.9
|
1.0
|
O
|
D:LYS134
|
4.0
|
24.6
|
1.0
|
NE2
|
D:HIS69
|
4.0
|
16.9
|
1.0
|
CD2
|
D:HIS78
|
4.1
|
17.4
|
1.0
|
CB
|
D:ASP81
|
4.2
|
13.8
|
1.0
|
CD2
|
D:HIS69
|
4.2
|
17.9
|
1.0
|
NE2
|
D:HIS61
|
4.2
|
17.3
|
1.0
|
CD2
|
D:HIS61
|
4.2
|
15.9
|
1.0
|
O
|
D:HOH350
|
4.6
|
22.0
|
1.0
|
CA
|
D:ASP81
|
4.7
|
13.4
|
1.0
|
N
|
D:HIS78
|
4.7
|
15.6
|
1.0
|
N
|
D:GLY70
|
4.7
|
19.9
|
1.0
|
CA
|
D:HIS78
|
4.8
|
14.0
|
1.0
|
CD2
|
D:HIS44
|
4.9
|
11.9
|
1.0
|
C
|
D:HIS69
|
4.9
|
21.0
|
1.0
|
C
|
D:LYS134
|
4.9
|
22.9
|
1.0
|
CA
|
D:HIS61
|
5.0
|
15.9
|
1.0
|
N
|
D:HIS69
|
5.0
|
20.0
|
1.0
|
N
|
D:ASP81
|
5.0
|
10.3
|
1.0
|
|
Zinc binding site 5 out
of 8 in 8iq1
Go back to
Zinc Binding Sites List in 8iq1
Zinc binding site 5 out
of 8 in the Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn202
b:16.8
occ:1.00
|
OD1
|
E:ASP81
|
1.9
|
14.1
|
1.0
|
ND1
|
E:HIS69
|
2.0
|
15.4
|
1.0
|
ND1
|
E:HIS61
|
2.0
|
15.0
|
1.0
|
ND1
|
E:HIS78
|
2.1
|
15.8
|
1.0
|
CG
|
E:ASP81
|
2.6
|
17.5
|
1.0
|
OD2
|
E:ASP81
|
2.7
|
14.3
|
1.0
|
CE1
|
E:HIS69
|
2.8
|
17.2
|
1.0
|
CE1
|
E:HIS61
|
2.9
|
15.3
|
1.0
|
CE1
|
E:HIS78
|
2.9
|
17.2
|
1.0
|
CG
|
E:HIS61
|
3.1
|
16.5
|
1.0
|
CG
|
E:HIS78
|
3.1
|
15.4
|
1.0
|
CG
|
E:HIS69
|
3.1
|
17.0
|
1.0
|
CB
|
E:HIS61
|
3.4
|
14.4
|
1.0
|
CB
|
E:HIS78
|
3.6
|
15.0
|
1.0
|
CB
|
E:HIS69
|
3.6
|
17.3
|
1.0
|
CA
|
E:HIS69
|
3.9
|
17.2
|
1.0
|
NE2
|
E:HIS69
|
4.0
|
17.6
|
1.0
|
O
|
E:LYS134
|
4.0
|
19.4
|
1.0
|
CB
|
E:ASP81
|
4.0
|
13.5
|
1.0
|
NE2
|
E:HIS78
|
4.0
|
18.3
|
1.0
|
NE2
|
E:HIS61
|
4.1
|
16.5
|
1.0
|
CD2
|
E:HIS78
|
4.2
|
14.9
|
1.0
|
CD2
|
E:HIS61
|
4.2
|
17.2
|
1.0
|
CD2
|
E:HIS69
|
4.2
|
17.4
|
1.0
|
N
|
E:GLY70
|
4.6
|
15.5
|
1.0
|
CA
|
E:ASP81
|
4.6
|
13.1
|
1.0
|
N
|
E:HIS78
|
4.6
|
14.1
|
1.0
|
CA
|
E:HIS78
|
4.7
|
15.6
|
1.0
|
C
|
E:HIS69
|
4.8
|
17.3
|
1.0
|
CD2
|
E:HIS44
|
4.9
|
14.2
|
1.0
|
N
|
E:ASP81
|
4.9
|
12.9
|
1.0
|
O
|
E:HOH378
|
4.9
|
19.9
|
1.0
|
N
|
E:HIS69
|
5.0
|
16.8
|
1.0
|
CA
|
E:HIS61
|
5.0
|
16.4
|
1.0
|
O
|
E:GLY70
|
5.0
|
18.4
|
1.0
|
|
Zinc binding site 6 out
of 8 in 8iq1
Go back to
Zinc Binding Sites List in 8iq1
Zinc binding site 6 out
of 8 in the Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Zn202
b:20.5
occ:1.00
|
ND1
|
F:HIS61
|
2.0
|
20.5
|
1.0
|
ND1
|
F:HIS78
|
2.0
|
18.5
|
1.0
|
OD1
|
F:ASP81
|
2.1
|
21.0
|
1.0
|
ND1
|
F:HIS69
|
2.2
|
24.3
|
1.0
|
CE1
|
F:HIS78
|
2.8
|
22.4
|
1.0
|
CG
|
F:ASP81
|
2.8
|
20.0
|
1.0
|
CE1
|
F:HIS61
|
2.9
|
21.8
|
1.0
|
CG
|
F:HIS61
|
3.0
|
20.2
|
1.0
|
CE1
|
F:HIS69
|
3.0
|
24.6
|
1.0
|
OD2
|
F:ASP81
|
3.0
|
20.7
|
1.0
|
CG
|
F:HIS78
|
3.1
|
19.5
|
1.0
|
CG
|
F:HIS69
|
3.3
|
25.8
|
1.0
|
CB
|
F:HIS61
|
3.4
|
18.6
|
1.0
|
CB
|
F:HIS78
|
3.6
|
18.8
|
1.0
|
CB
|
F:HIS69
|
3.7
|
25.2
|
1.0
|
NE2
|
F:HIS78
|
4.0
|
19.9
|
1.0
|
NE2
|
F:HIS61
|
4.0
|
22.0
|
1.0
|
O
|
F:LYS134
|
4.0
|
27.8
|
1.0
|
CA
|
F:HIS69
|
4.0
|
25.1
|
1.0
|
CD2
|
F:HIS61
|
4.1
|
21.2
|
1.0
|
CD2
|
F:HIS78
|
4.1
|
18.4
|
1.0
|
NE2
|
F:HIS69
|
4.2
|
27.3
|
1.0
|
CB
|
F:ASP81
|
4.3
|
18.4
|
1.0
|
CD2
|
F:HIS69
|
4.3
|
26.6
|
1.0
|
CA
|
F:ASP81
|
4.7
|
18.3
|
1.0
|
N
|
F:HIS78
|
4.8
|
20.6
|
1.0
|
N
|
F:GLY70
|
4.8
|
26.0
|
1.0
|
CA
|
F:HIS78
|
4.8
|
19.9
|
1.0
|
CA
|
F:HIS61
|
4.9
|
17.6
|
1.0
|
CD2
|
F:HIS44
|
4.9
|
20.9
|
1.0
|
O
|
F:HOH378
|
5.0
|
28.0
|
1.0
|
C
|
F:HIS69
|
5.0
|
26.8
|
1.0
|
|
Zinc binding site 7 out
of 8 in 8iq1
Go back to
Zinc Binding Sites List in 8iq1
Zinc binding site 7 out
of 8 in the Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Zn202
b:19.6
occ:1.00
|
ND1
|
G:HIS78
|
1.9
|
20.1
|
1.0
|
ND1
|
G:HIS61
|
2.0
|
19.4
|
1.0
|
ND1
|
G:HIS69
|
2.1
|
21.5
|
1.0
|
OD1
|
G:ASP81
|
2.1
|
16.4
|
1.0
|
CE1
|
G:HIS78
|
2.6
|
22.2
|
1.0
|
CG
|
G:ASP81
|
2.8
|
17.0
|
1.0
|
OD2
|
G:ASP81
|
2.9
|
19.4
|
1.0
|
CE1
|
G:HIS69
|
2.9
|
22.7
|
1.0
|
CE1
|
G:HIS61
|
3.0
|
19.7
|
1.0
|
CG
|
G:HIS61
|
3.1
|
18.2
|
1.0
|
CG
|
G:HIS78
|
3.1
|
21.1
|
1.0
|
CG
|
G:HIS69
|
3.1
|
22.8
|
1.0
|
CB
|
G:HIS61
|
3.4
|
16.1
|
1.0
|
CB
|
G:HIS69
|
3.5
|
25.8
|
1.0
|
CB
|
G:HIS78
|
3.7
|
18.9
|
1.0
|
NE2
|
G:HIS78
|
3.8
|
20.8
|
1.0
|
O
|
G:LYS134
|
3.8
|
30.0
|
1.0
|
CA
|
G:HIS69
|
3.8
|
27.9
|
1.0
|
CD2
|
G:HIS78
|
4.0
|
20.1
|
1.0
|
NE2
|
G:HIS69
|
4.1
|
22.1
|
1.0
|
NE2
|
G:HIS61
|
4.1
|
20.6
|
1.0
|
CD2
|
G:HIS61
|
4.2
|
19.0
|
1.0
|
CD2
|
G:HIS69
|
4.2
|
23.4
|
1.0
|
CB
|
G:ASP81
|
4.3
|
14.8
|
1.0
|
N
|
G:GLY70
|
4.7
|
29.9
|
1.0
|
N
|
G:HIS78
|
4.7
|
19.2
|
1.0
|
CA
|
G:ASP81
|
4.8
|
18.3
|
1.0
|
CA
|
G:HIS78
|
4.8
|
20.5
|
1.0
|
N
|
G:HIS69
|
4.8
|
28.7
|
1.0
|
C
|
G:LYS134
|
4.8
|
31.9
|
1.0
|
C
|
G:HIS69
|
4.8
|
32.3
|
1.0
|
CD2
|
G:HIS44
|
4.9
|
19.6
|
1.0
|
CA
|
G:HIS61
|
4.9
|
16.7
|
1.0
|
|
Zinc binding site 8 out
of 8 in 8iq1
Go back to
Zinc Binding Sites List in 8iq1
Zinc binding site 8 out
of 8 in the Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Crystal Structure of Hydrogen Sulfide-Bound Superoxide Dismutase in Reduced State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:Zn202
b:18.4
occ:1.00
|
OD1
|
H:ASP81
|
1.8
|
20.4
|
1.0
|
ND1
|
H:HIS61
|
2.1
|
20.9
|
1.0
|
ND1
|
H:HIS78
|
2.2
|
21.9
|
1.0
|
ND1
|
H:HIS69
|
2.2
|
27.5
|
1.0
|
CG
|
H:ASP81
|
2.6
|
20.5
|
1.0
|
OD2
|
H:ASP81
|
2.8
|
22.8
|
1.0
|
CE1
|
H:HIS69
|
3.0
|
27.2
|
1.0
|
CG
|
H:HIS78
|
3.0
|
22.1
|
1.0
|
CG
|
H:HIS61
|
3.0
|
22.8
|
1.0
|
CE1
|
H:HIS78
|
3.1
|
21.0
|
1.0
|
CE1
|
H:HIS61
|
3.2
|
22.3
|
1.0
|
CG
|
H:HIS69
|
3.3
|
29.6
|
1.0
|
CB
|
H:HIS61
|
3.3
|
23.3
|
1.0
|
CB
|
H:HIS78
|
3.3
|
20.7
|
1.0
|
CB
|
H:HIS69
|
3.7
|
27.2
|
1.0
|
CA
|
H:HIS69
|
4.0
|
25.5
|
1.0
|
CB
|
H:ASP81
|
4.0
|
20.2
|
1.0
|
CD2
|
H:HIS78
|
4.2
|
20.2
|
1.0
|
NE2
|
H:HIS78
|
4.2
|
21.9
|
1.0
|
NE2
|
H:HIS69
|
4.2
|
27.6
|
1.0
|
CD2
|
H:HIS61
|
4.2
|
22.7
|
1.0
|
NE2
|
H:HIS61
|
4.2
|
24.8
|
1.0
|
O
|
H:LYS134
|
4.3
|
31.0
|
1.0
|
CD2
|
H:HIS69
|
4.3
|
28.6
|
1.0
|
CA
|
H:ASP81
|
4.5
|
20.3
|
1.0
|
N
|
H:HIS78
|
4.5
|
23.1
|
1.0
|
CA
|
H:HIS78
|
4.5
|
22.2
|
1.0
|
N
|
H:GLY70
|
4.8
|
26.7
|
1.0
|
N
|
H:ASP81
|
4.8
|
19.4
|
1.0
|
O1
|
H:EDO203
|
4.8
|
34.3
|
1.0
|
CA
|
H:HIS61
|
4.8
|
25.8
|
1.0
|
CD2
|
H:HIS44
|
4.8
|
21.6
|
1.0
|
C
|
H:HIS69
|
4.9
|
27.8
|
1.0
|
|
Reference:
D.D.Wu,
S.Jin,
R.X.Cheng,
W.J.Cai,
W.L.Xue,
Q.Q.Zhang,
L.J.Yang,
Q.Zhu,
M.Y.Li,
G.Lin,
Y.Z.Wang,
X.P.Mu,
Y.Wang,
I.Y.Zhang,
Q.Zhang,
Y.Chen,
S.Y.Cai,
B.Tan,
Y.Li,
Y.Q.Chen,
P.J.Zhang,
C.Sun,
Y.Yin,
M.J.Wang,
Y.Z.Zhu,
B.B.Tao,
J.H.Zhou,
W.X.Huang,
Y.C.Zhu.
Hydrogen Sulfide Functions As A Micro-Modulator Bound at the Copper Active Site of Cu/Zn-Sod to Regulate the Catalytic Activity of the Enzyme. Cell Rep V. 42 12750 2023.
ISSN: ESSN 2211-1247
PubMed: 37421623
DOI: 10.1016/J.CELREP.2023.112750
Page generated: Thu Oct 31 07:55:30 2024
|