Zinc in PDB 8idf: Crystal Structure of Human TUT1 Complexed with U6 Snrna

All present enzymatic activity of Crystal Structure of Human TUT1 Complexed with U6 Snrna:
2.7.7.19; 2.7.7.52;

The structure of Crystal Structure of Human TUT1 Complexed with U6 Snrna, PDB code: 8idf was solved by S.Yamashita, K.Tomita, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.99 / 3.70
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	78.724, 78.724, 370.272, 90, 90, 120
R / Rfree (%)	30.5 / 33.9

The binding sites of Zinc atom in the Crystal Structure of Human TUT1 Complexed with U6 Snrna (pdb code 8idf). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human TUT1 Complexed with U6 Snrna, PDB code: 8idf:

Zinc binding site 1 out of 1 in the Crystal Structure of Human TUT1 Complexed with U6 Snrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human TUT1 Complexed with U6 Snrna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:170.1 occ:1.00 ND1 A:HIS40 2.0 162.1 1.0 NE2 A:HIS34 2.0 185.0 1.0 SG A:CYS18 2.3 238.4 1.0 SG A:CYS21 2.3 142.0 1.0 CE1 A:HIS34 2.9 169.5 1.0 CE1 A:HIS40 2.9 158.0 1.0 CB A:CYS21 3.0 164.0 1.0 CG A:HIS40 3.1 163.3 1.0 CD2 A:HIS34 3.2 176.6 1.0 CB A:CYS18 3.6 261.8 1.0 CB A:HIS40 3.6 163.9 1.0 N A:CYS21 3.7 178.1 1.0 CA A:CYS21 4.0 170.6 1.0 ND1 A:HIS34 4.0 142.5 1.0 NE2 A:HIS40 4.1 159.4 1.0 CD2 A:HIS40 4.2 163.8 1.0 CA A:HIS40 4.2 181.7 1.0 CG A:HIS34 4.2 160.1 1.0 C A:LEU20 4.3 173.3 1.0 CB A:LEU20 4.3 167.0 1.0 CD2 A:LEU35 4.7 157.3 1.0 CA A:LEU20 4.8 176.4 1.0 CG A:LEU20 4.8 154.8 1.0 CA A:CYS18 4.9 270.6 1.0 O A:LEU20 5.0 146.9 1.0

S.Yamashita, K.Tomita. Mechanism of U6 Snrna Oligouridylation By Human TUT1 Nat Commun 2023.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-023-40420-9