Zinc in PDB 8guj: BRE1-Nucleosome Complex (Model II)

All present enzymatic activity of BRE1-Nucleosome Complex (Model II):
2.3.2.27;

The binding sites of Zinc atom in the BRE1-Nucleosome Complex (Model II) (pdb code 8guj). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the BRE1-Nucleosome Complex (Model II), PDB code: 8guj:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the BRE1-Nucleosome Complex (Model II)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of BRE1-Nucleosome Complex (Model II) within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn1001 b:155.0 occ:1.00 ND1 K:HIS939 2.1 139.4 1.0 SG K:CYS960 2.3 144.8 1.0 SG K:CYS957 2.3 144.9 1.0 SG K:CYS937 2.3 139.5 1.0 CE1 K:HIS939 2.9 139.4 1.0 CB K:CYS937 3.0 139.5 1.0 CG K:HIS939 3.2 139.4 1.0 CB K:CYS957 3.3 144.9 1.0 CB K:CYS960 3.4 144.8 1.0 CB K:HIS939 3.7 139.4 1.0 N K:CYS960 4.0 144.8 1.0 CG K:LYS959 4.1 143.0 1.0 NE2 K:HIS939 4.1 139.4 1.0 NZ K:LYS959 4.2 143.0 1.0 CA K:CYS960 4.3 144.8 1.0 CD2 K:HIS939 4.3 139.4 1.0 CE K:LYS959 4.3 143.0 1.0 CD1 K:LEU934 4.3 138.2 1.0 CA K:CYS937 4.4 139.5 1.0 O K:CYS937 4.7 139.5 1.0 CA K:CYS957 4.8 144.9 1.0 C K:CYS937 4.8 139.5 1.0 CB K:ALA962 4.8 143.1 1.0 CD K:LYS959 4.8 143.0 1.0 C K:CYS960 4.9 144.8 1.0 CZ K:PHE941 5.0 144.4 1.0

Zinc binding site 2 out of 4 in the BRE1-Nucleosome Complex (Model II)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of BRE1-Nucleosome Complex (Model II) within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn1002 b:163.4 occ:1.00 SG K:CYS945 2.3 146.5 1.0 SG K:CYS942 2.3 146.3 1.0 SG K:CYS922 2.3 153.0 1.0 SG K:CYS925 2.3 153.0 1.0 CB K:CYS922 2.5 153.0 1.0 NH1 K:ARG928 2.5 150.7 1.0 CB K:CYS925 2.9 153.0 1.0 CB K:CYS945 3.0 146.5 1.0 CB K:CYS942 3.5 146.3 1.0 CZ K:ARG928 3.7 150.7 1.0 N K:CYS925 3.8 153.0 1.0 CA K:CYS925 3.9 153.0 1.0 SG K:CYS924 4.0 153.0 1.0 CA K:CYS922 4.1 153.0 1.0 CA K:CYS945 4.3 146.5 1.0 N K:CYS942 4.4 146.3 1.0 CG K:ARG928 4.5 150.7 1.0 N K:CYS945 4.5 146.5 1.0 CA K:CYS942 4.5 146.3 1.0 NH2 K:ARG928 4.5 150.7 1.0 NE K:ARG928 4.5 150.7 1.0 CD K:ARG928 4.6 150.7 1.0 N K:ASN926 4.8 152.7 1.0 N K:CYS922 4.8 153.0 1.0 C K:CYS922 4.8 153.0 1.0 C K:CYS925 4.8 153.0 1.0

Zinc binding site 3 out of 4 in the BRE1-Nucleosome Complex (Model II)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of BRE1-Nucleosome Complex (Model II) within 5.0Å range: probe atom residue distance (Å) B Occ L:Zn1101 b:117.4 occ:1.00 ND1 L:HIS965 2.1 113.0 1.0 SG L:CYS983 2.3 98.7 1.0 SG L:CYS963 2.3 109.2 1.0 SG L:CYS986 2.3 103.9 1.0 CB L:CYS963 2.7 109.2 1.0 CE1 L:HIS965 2.8 113.0 1.0 CB L:CYS983 3.1 98.7 1.0 CB L:CYS986 3.3 103.9 1.0 CG L:HIS965 3.3 113.0 1.0 CB L:HIS965 3.8 113.0 1.0 N L:CYS986 3.8 103.9 1.0 CG L:LYS985 4.0 105.1 1.0 CA L:CYS963 4.0 109.2 1.0 NE2 L:HIS965 4.0 113.0 1.0 CA L:CYS986 4.0 103.9 1.0 O L:CYS963 4.1 109.2 1.0 CD2 L:HIS965 4.3 113.0 1.0 C L:CYS963 4.3 109.2 1.0 NZ L:LYS985 4.5 105.1 1.0 CE1 L:PHE967 4.5 117.0 1.0 CZ L:PHE967 4.5 117.0 1.0 CA L:CYS983 4.5 98.7 1.0 C L:CYS986 4.6 103.9 1.0 CD L:LYS985 4.7 105.1 1.0 N L:ASN987 4.8 98.4 1.0 CD1 L:LEU960 4.9 106.5 1.0 N L:HIS965 4.9 113.0 1.0 CB L:ALA988 4.9 95.9 1.0 C L:LYS985 5.0 105.1 1.0 CA L:HIS965 5.0 113.0 1.0 N L:CYS963 5.0 109.2 1.0

Zinc binding site 4 out of 4 in the BRE1-Nucleosome Complex (Model II)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of BRE1-Nucleosome Complex (Model II) within 5.0Å range: probe atom residue distance (Å) B Occ L:Zn1102 b:140.4 occ:1.00 SG L:CYS971 2.3 112.1 1.0 SG L:CYS951 2.3 130.9 1.0 SG L:CYS948 2.3 132.3 1.0 SG L:CYS968 2.3 118.9 1.0 NH1 L:ARG954 2.5 128.3 1.0 CB L:CYS948 2.6 132.3 1.0 CB L:CYS971 3.0 112.1 1.0 CB L:CYS951 3.2 130.9 1.0 CZ L:ARG954 3.5 128.3 1.0 CB L:CYS968 3.6 118.9 1.0 NH2 L:ARG954 3.7 128.3 1.0 SG L:CYS950 3.8 128.0 1.0 CA L:CYS948 4.0 132.3 1.0 N L:CYS951 4.1 130.9 1.0 N L:CYS968 4.1 118.9 1.0 CA L:CYS951 4.3 130.9 1.0 CA L:CYS971 4.3 112.1 1.0 O L:CYS948 4.4 132.3 1.0 CA L:CYS968 4.4 118.9 1.0 C L:CYS948 4.4 132.3 1.0 N L:CYS971 4.5 112.1 1.0 NE L:ARG954 4.7 128.3 1.0 O L:CYS968 4.7 118.9 1.0 N L:CYS948 4.7 132.3 1.0 O L:ARG954 4.9 128.3 1.0 C L:CYS968 4.9 118.9 1.0

S.Onishi, K.Uchiyama, K.Sato, C.Okada, S.Kobayashi, K.Hamada, T.Nishizawa, K.Ogata, T.Sengoku. Structure of the Human BRE1 Complex Bound to the Nucleosome To Be Published.