Zinc in PDB 8gio: Structure of Ternary Complex of Mouse Cgas with Dsdna and Bound Atp: with 10MM MG2+ and 0.1MM MN2+

All present enzymatic activity of Structure of Ternary Complex of Mouse Cgas with Dsdna and Bound Atp: with 10MM MG2+ and 0.1MM MN2+:
2.7.7.86;

The structure of Structure of Ternary Complex of Mouse Cgas with Dsdna and Bound Atp: with 10MM MG2+ and 0.1MM MN2+, PDB code: 8gio was solved by S.Wu, J.Sohn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.80 / 2.67
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	77.594, 98.624, 141.929, 90, 90, 90
R / Rfree (%)	18.3 / 24.1

The structure of Structure of Ternary Complex of Mouse Cgas with Dsdna and Bound Atp: with 10MM MG2+ and 0.1MM MN2+ also contains other interesting chemical elements:

Manganese

(Mn)

4 atoms

The binding sites of Zinc atom in the Structure of Ternary Complex of Mouse Cgas with Dsdna and Bound Atp: with 10MM MG2+ and 0.1MM MN2+ (pdb code 8gio). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Ternary Complex of Mouse Cgas with Dsdna and Bound Atp: with 10MM MG2+ and 0.1MM MN2+, PDB code: 8gio:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Ternary Complex of Mouse Cgas with Dsdna and Bound Atp: with 10MM MG2+ and 0.1MM MN2+


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Ternary Complex of Mouse Cgas with Dsdna and Bound Atp: with 10MM MG2+ and 0.1MM MN2+ within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn602 b:50.4 occ:1.00 NE2 A:HIS378 2.0 42.6 1.0 SG A:CYS385 2.3 43.4 1.0 SG A:CYS384 2.3 39.8 1.0 SG A:CYS392 2.3 40.7 1.0 CD2 A:HIS378 2.9 37.4 1.0 CE1 A:HIS378 3.1 38.7 1.0 CB A:CYS392 3.2 41.6 1.0 CB A:CYS385 3.2 41.1 1.0 CB A:CYS384 3.7 36.3 1.0 N A:CYS392 3.8 42.7 1.0 N A:CYS385 3.8 39.1 1.0 C A:CYS384 3.8 39.0 1.0 CA A:CYS392 4.0 41.5 1.0 CA A:CYS385 4.0 39.0 1.0 CG A:HIS378 4.1 42.0 1.0 ND1 A:HIS378 4.1 39.9 1.0 O A:CYS384 4.2 38.9 1.0 CA A:CYS384 4.3 37.5 1.0 NH1 A:ARG394 4.4 40.8 1.0 C A:CYS392 4.5 42.6 1.0 O A:CYS392 4.6 48.9 1.0 O A:ALA390 4.8 45.0 1.0 C A:LYS391 4.9 46.7 1.0

Zinc binding site 2 out of 2 in the Structure of Ternary Complex of Mouse Cgas with Dsdna and Bound Atp: with 10MM MG2+ and 0.1MM MN2+


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Ternary Complex of Mouse Cgas with Dsdna and Bound Atp: with 10MM MG2+ and 0.1MM MN2+ within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn602 b:49.0 occ:1.00 NE2 C:HIS378 2.1 46.1 1.0 SG C:CYS385 2.3 46.0 1.0 SG C:CYS384 2.3 45.9 1.0 SG C:CYS392 2.4 44.1 1.0 CD2 C:HIS378 3.0 42.3 1.0 CE1 C:HIS378 3.2 40.3 1.0 CB C:CYS385 3.2 46.3 1.0 CB C:CYS392 3.3 46.9 1.0 CB C:CYS384 3.8 42.1 1.0 N C:CYS392 3.8 45.2 1.0 C C:CYS384 3.8 44.8 1.0 N C:CYS385 3.9 46.8 1.0 O C:CYS384 4.1 42.3 1.0 CA C:CYS392 4.1 47.8 1.0 CA C:CYS385 4.1 46.2 1.0 CG C:HIS378 4.2 44.7 1.0 NH1 C:ARG394 4.2 46.8 1.0 ND1 C:HIS378 4.3 44.5 1.0 CA C:CYS384 4.3 42.1 1.0 C C:CYS392 4.6 49.5 1.0 O C:ALA390 4.7 51.4 1.0 O C:CYS392 4.8 52.4 1.0 C C:LYS391 4.8 49.0 1.0

S.Wu, J.Sohn. Structure of Ternary Complex of Mouse Cgas with Dsdna and Bound Atp: with 10MM MG2+ and 0.1MM MN2+ To Be Published.