Zinc in PDB 8fxc: Sars-Cov-2 Bq.1.1 Spike Rbd Bound to the Human ACE2 Ectodomain and the S309 Neutralizing Antibody Fab Fragment

The binding sites of Zinc atom in the Sars-Cov-2 Bq.1.1 Spike Rbd Bound to the Human ACE2 Ectodomain and the S309 Neutralizing Antibody Fab Fragment (pdb code 8fxc). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Sars-Cov-2 Bq.1.1 Spike Rbd Bound to the Human ACE2 Ectodomain and the S309 Neutralizing Antibody Fab Fragment, PDB code: 8fxc:

Zinc binding site 1 out of 1 in the Sars-Cov-2 Bq.1.1 Spike Rbd Bound to the Human ACE2 Ectodomain and the S309 Neutralizing Antibody Fab Fragment


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sars-Cov-2 Bq.1.1 Spike Rbd Bound to the Human ACE2 Ectodomain and the S309 Neutralizing Antibody Fab Fragment within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn706 b:18.8 occ:1.00 NE2 A:HIS378 2.0 17.7 1.0 NE2 A:HIS374 2.5 18.2 1.0 OE1 A:GLU402 2.6 17.7 1.0 CE1 A:HIS378 2.8 17.4 1.0 OE2 A:GLU402 3.1 17.7 1.0 CD A:GLU402 3.2 17.6 1.0 CD2 A:HIS378 3.2 18.0 1.0 CD2 A:HIS374 3.3 18.5 1.0 CE1 A:HIS374 3.5 18.2 1.0 ND1 A:HIS378 4.0 17.3 1.0 CG A:HIS378 4.2 17.6 1.0 CG A:HIS374 4.4 18.5 1.0 OE2 A:GLU375 4.5 19.2 1.0 ND1 A:HIS374 4.6 18.4 1.0 CG A:GLU402 4.6 17.2 1.0

A.Addetia, L.Piccoli, J.B.Case, Y.J.Park, M.Beltramello, B.Guarino, H.Dang, G.D.De Melo, D.Pinto, K.Sprouse, S.M.Scheaffer, J.Bassi, C.Silacci-Fregni, F.Muoio, M.Dini, L.Vincenzetti, R.Acosta, D.Johnson, S.Subramanian, C.Saliba, M.Giurdanella, G.Lombardo, G.Leoni, K.Culap, C.Mcalister, A.Rajesh, E.Dellota Jr., J.Zhou, N.Farhat, D.Bohan, J.Noack, A.Chen, F.A.Lempp, J.Quispe, L.Kergoat, F.Larrous, E.Cameroni, B.Whitener, O.Giannini, P.Cippa, A.Ceschi, P.Ferrari, A.Franzetti-Pellanda, M.Biggiogero, C.Garzoni, S.Zappi, L.Bernasconi, M.J.Kim, L.E.Rosen, G.Schnell, N.Czudnochowski, F.Benigni, N.Franko, J.K.Logue, C.Yoshiyama, C.Stewart, H.Chu, H.Bourhy, M.A.Schmid, L.A.Purcell, G.Snell, A.Lanzavecchia, M.S.Diamond, D.Corti, D.Veesler. Neutralization, Effector Function and Immune Imprinting of Omicron Variants. Nature V. 621 592 2023.
ISSN: ESSN 1476-4687
PubMed: 37648855
DOI: 10.1038/S41586-023-06487-6