Zinc in PDB 8f5p: Structure of Leishmania Tarentolae Ift-A (State 2)

The binding sites of Zinc atom in the Structure of Leishmania Tarentolae Ift-A (State 2) (pdb code 8f5p). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Structure of Leishmania Tarentolae Ift-A (State 2), PDB code: 8f5p:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Structure of Leishmania Tarentolae Ift-A (State 2)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Leishmania Tarentolae Ift-A (State 2) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn3000 b:200.0 occ:1.00 SG B:CYS1188 2.3 125.0 1.0 SG B:CYS1174 2.3 137.2 1.0 SG B:CYS1177 2.3 140.1 1.0 SG B:CYS1191 2.3 132.7 1.0 CB B:CYS1177 2.7 140.1 1.0 CB B:CYS1174 2.7 137.2 1.0 CB B:CYS1191 2.9 132.7 1.0 N B:CYS1177 3.3 140.1 1.0 CA B:CYS1177 3.6 140.1 1.0 CB B:CYS1188 3.6 125.0 1.0 N B:CYS1191 3.7 132.7 1.0 CA B:CYS1191 3.9 132.7 1.0 CG B:LYS1190 4.2 127.2 1.0 CA B:CYS1174 4.2 137.2 1.0 N B:GLY1178 4.5 133.7 1.0 C B:THR1176 4.5 139.2 1.0 C B:CYS1177 4.5 140.1 1.0 OG B:SER1179 4.5 122.4 1.0 CB B:THR1176 4.7 139.2 1.0 C B:CYS1174 4.8 137.2 1.0 N B:THR1176 4.8 139.2 1.0 CA B:CYS1188 4.8 125.0 1.0 C B:LYS1190 4.9 127.2 1.0 CA B:THR1176 4.9 139.2 1.0 C B:CYS1191 4.9 132.7 1.0 N B:LYS1190 5.0 127.2 1.0

Zinc binding site 2 out of 4 in the Structure of Leishmania Tarentolae Ift-A (State 2)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Leishmania Tarentolae Ift-A (State 2) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn3001 b:97.7 occ:1.00 SG B:CYS1217 2.3 94.9 1.0 SG B:CYS1232 2.3 105.0 1.0 SG B:CYS1214 2.3 106.0 1.0 SG B:CYS1235 2.3 97.0 1.0 CB B:CYS1232 2.8 105.0 1.0 CB B:CYS1214 3.0 106.0 1.0 CB B:CYS1217 3.5 94.9 1.0 CB B:CYS1235 3.7 97.0 1.0 N B:CYS1217 3.8 94.9 1.0 N B:CYS1235 3.9 97.0 1.0 CA B:CYS1232 4.2 105.0 1.0 CA B:CYS1217 4.3 94.9 1.0 CA B:CYS1235 4.3 97.0 1.0 CA B:CYS1214 4.4 106.0 1.0 CB B:VAL1216 4.5 87.5 1.0 C B:CYS1232 4.7 105.0 1.0 CB B:LEU1234 4.7 92.7 1.0 O B:CYS1232 4.8 105.0 1.0 C B:VAL1216 4.8 87.5 1.0 C B:CYS1214 4.9 106.0 1.0 N B:VAL1216 4.9 87.5 1.0 N B:HIS1236 4.9 105.8 1.0 C B:CYS1235 4.9 97.0 1.0 CA B:VAL1216 5.0 87.5 1.0

Zinc binding site 3 out of 4 in the Structure of Leishmania Tarentolae Ift-A (State 2)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of Leishmania Tarentolae Ift-A (State 2) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn3000 b:272.7 occ:1.00 SG C:CYS1064 2.3 230.2 1.0 SG C:CYS1044 2.3 221.0 1.0 SG C:CYS1061 2.3 218.7 1.0 SG C:CYS1047 2.3 224.8 1.0 CB C:CYS1064 2.7 230.2 1.0 CB C:CYS1061 2.8 218.7 1.0 CB C:CYS1047 3.0 224.8 1.0 CB C:CYS1044 3.4 221.0 1.0 N C:CYS1064 3.4 230.2 1.0 CA C:CYS1064 3.7 230.2 1.0 N C:CYS1047 3.7 224.8 1.0 CA C:CYS1047 4.0 224.8 1.0 C C:ASN1063 4.2 227.9 1.0 CA C:CYS1061 4.3 218.7 1.0 CB C:ASN1063 4.4 227.9 1.0 CB C:ARG1046 4.5 218.2 1.0 C C:CYS1064 4.6 230.2 1.0 N C:ASN1063 4.6 227.9 1.0 C C:ARG1046 4.7 218.2 1.0 CA C:ASN1063 4.7 227.9 1.0 C C:CYS1061 4.8 218.7 1.0 CA C:CYS1044 4.8 221.0 1.0 N C:PHE1065 4.8 222.3 1.0 CD C:ARG1046 4.9 218.2 1.0

Zinc binding site 4 out of 4 in the Structure of Leishmania Tarentolae Ift-A (State 2)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structure of Leishmania Tarentolae Ift-A (State 2) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn3001 b:195.6 occ:1.00 SG C:CYS1232 2.3 149.3 1.0 SG C:CYS1235 2.3 151.4 1.0 SG C:CYS1257 2.3 130.9 1.0 SG C:CYS1254 2.3 132.3 1.0 CB C:CYS1232 2.6 149.3 1.0 CB C:CYS1235 2.7 151.4 1.0 CB C:CYS1257 3.1 130.9 1.0 CB C:CYS1254 3.2 132.3 1.0 N C:CYS1235 3.7 151.4 1.0 CA C:CYS1235 3.8 151.4 1.0 N C:CYS1257 4.0 130.9 1.0 CA C:CYS1232 4.1 149.3 1.0 CA C:CYS1257 4.2 130.9 1.0 C C:GLY1234 4.4 150.0 1.0 CE1 C:PHE1239 4.4 140.3 1.0 C C:CYS1232 4.6 149.3 1.0 CZ C:PHE1239 4.6 140.3 1.0 CA C:CYS1254 4.7 132.3 1.0 O C:CYS1232 4.7 149.3 1.0 N C:GLY1234 4.8 150.0 1.0 C C:CYS1235 4.8 151.4 1.0 N C:CYS1232 4.9 149.3 1.0 CB C:LEU1256 4.9 127.5 1.0 CA C:GLY1234 4.9 150.0 1.0 N C:GLN1236 4.9 148.0 1.0 C C:LEU1256 5.0 127.5 1.0

S.Meleppattu, H.Zhou, J.Dai, M.Gui, A.Brown. Mechanism of Ift-A Polymerization Into Trains For Ciliary Transport Cell(Cambridge,Mass.) 2022.
ISSN: ISSN 0092-8674
DOI: 10.1016/J.CELL.2022.11.033