Zinc in PDB 8exs: Cryo-Em Structure of S. Aureus BLAR1 F284A Mutant

The binding sites of Zinc atom in the Cryo-Em Structure of S. Aureus BLAR1 F284A Mutant (pdb code 8exs). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of S. Aureus BLAR1 F284A Mutant, PDB code: 8exs:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of S. Aureus BLAR1 F284A Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of S. Aureus BLAR1 F284A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:75.5 occ:1.00 OE2 A:GLU242 2.1 5.3 1.0 OE1 A:GLU242 2.1 5.3 1.0 NE2 A:HIS201 2.3 8.9 1.0 NE2 A:HIS205 2.3 29.1 1.0 CD A:GLU242 2.4 5.3 1.0 CD2 A:HIS205 2.9 29.1 1.0 CE1 A:HIS201 3.1 8.9 1.0 CD2 A:HIS201 3.1 8.9 1.0 OE2 A:GLU202 3.2 4.0 1.0 CE1 A:HIS205 3.4 29.1 1.0 OE1 A:GLU202 3.6 4.0 1.0 CD A:GLU202 3.8 4.0 1.0 CG A:GLU242 4.0 5.3 1.0 ND1 A:HIS201 4.0 8.9 1.0 CG A:HIS201 4.0 8.9 1.0 CG A:HIS205 4.1 29.1 1.0 CB A:HIS282 4.2 6.0 1.0 ND1 A:HIS205 4.2 29.1 1.0 ND1 A:HIS282 4.3 6.0 1.0 CG A:HIS282 4.4 6.0 1.0 O A:SER283 4.7 29.1 1.0 CB A:GLU242 4.8 5.3 1.0 O A:HIS201 4.9 8.9 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of S. Aureus BLAR1 F284A Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of S. Aureus BLAR1 F284A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn701 b:75.5 occ:1.00 OE2 B:GLU242 2.1 5.3 1.0 OE1 B:GLU242 2.1 5.3 1.0 NE2 B:HIS201 2.3 8.9 1.0 NE2 B:HIS205 2.3 29.1 1.0 CD B:GLU242 2.4 5.3 1.0 CD2 B:HIS205 2.9 29.1 1.0 CE1 B:HIS201 3.1 8.9 1.0 CD2 B:HIS201 3.1 8.9 1.0 OE2 B:GLU202 3.2 4.0 1.0 CE1 B:HIS205 3.4 29.1 1.0 OE1 B:GLU202 3.6 4.0 1.0 CD B:GLU202 3.8 4.0 1.0 CG B:GLU242 4.0 5.3 1.0 ND1 B:HIS201 4.0 8.9 1.0 CG B:HIS201 4.0 8.9 1.0 CG B:HIS205 4.1 29.1 1.0 CB B:HIS282 4.2 6.0 1.0 ND1 B:HIS205 4.2 29.1 1.0 ND1 B:HIS282 4.3 6.0 1.0 CG B:HIS282 4.4 6.0 1.0 O B:SER283 4.7 29.1 1.0 CB B:GLU242 4.8 5.3 1.0 O B:HIS201 4.9 8.9 1.0

J.A.N.Alexander, L.J.Worrall, J.Hu, M.Vuckovic, N.Satishkumar, R.Poon, S.Sobhanifar, F.I.Rosell, J.Jenkins, D.Chiang, W.A.Mosimann, H.F.Chambers, M.Paetzel, S.S.Chatterjee, N.C.J.Strynadka. Structural Basis of Broad-Spectrum Beta-Lactam Resistance in Staphylococcus Aureus Nature 2023.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-022-05583-3