Zinc in PDB 8dtu: The Complex of Nanobody 5344N74D with BCL11A ZF6.

The structure of The Complex of Nanobody 5344N74D with BCL11A ZF6., PDB code: 8dtu was solved by M.Yin, K.Tenglin, L.Zhai, L.M.Dassama, S.H.Orkin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.66 / 2.45
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	57.507, 57.507, 157.328, 90, 90, 90
R / Rfree (%)	26.1 / 28.8

The binding sites of Zinc atom in the The Complex of Nanobody 5344N74D with BCL11A ZF6. (pdb code 8dtu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the The Complex of Nanobody 5344N74D with BCL11A ZF6., PDB code: 8dtu:

Zinc binding site 1 out of 1 in the The Complex of Nanobody 5344N74D with BCL11A ZF6.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Complex of Nanobody 5344N74D with BCL11A ZF6. within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn901 b:92.5 occ:1.00 NE2 C:HIS818 2.0 59.2 1.0 NE2 C:HIS823 2.1 72.7 1.0 SG C:CYS805 2.1 52.5 1.0 SG C:CYS802 2.5 59.1 1.0 CD2 C:HIS818 2.8 66.0 1.0 CD2 C:HIS823 3.0 66.8 1.0 CE1 C:HIS823 3.1 65.0 1.0 CE1 C:HIS818 3.2 60.8 1.0 CB C:CYS805 3.3 51.1 1.0 CB C:CYS802 3.4 54.9 1.0 N C:CYS805 3.5 52.8 1.0 CA C:CYS805 4.0 55.2 1.0 CG C:HIS818 4.1 66.5 1.0 CB C:ILE804 4.1 58.6 1.0 CG C:HIS823 4.1 67.8 1.0 ND1 C:HIS823 4.2 65.0 1.0 ND1 C:HIS818 4.2 62.4 1.0 C C:ILE804 4.5 55.8 1.0 CG1 C:ILE804 4.7 58.9 1.0 CA C:ILE804 4.7 58.6 1.0 N C:ILE804 4.7 50.8 1.0 CA C:CYS802 4.8 60.7 1.0 C C:CYS805 4.9 57.1 1.0

M.Yin, M.Izadi, K.Tenglin, T.Viennet, L.Zhai, G.Zheng, H.Arthanari, L.M.K.Dassama, S.H.Orkin. Evolution of Nanobodies Specific For BCL11A. Proc.Natl.Acad.Sci.Usa V. 120 59120 2023.
ISSN: ESSN 1091-6490
PubMed: 36626555
DOI: 10.1073/PNAS.2218959120