Zinc in PDB 8dgs: Cryo-Em Structure of A Ras/Raf Complex (State 1)

All present enzymatic activity of Cryo-Em Structure of A Ras/Raf Complex (State 1):
2.7.11.1; 2.7.12.2;

The structure of Cryo-Em Structure of A Ras/Raf Complex (State 1) also contains other interesting chemical elements:

Iodine	(I)	1 atom
Fluorine	(F)	1 atom
Magnesium	(Mg)	2 atoms

The binding sites of Zinc atom in the Cryo-Em Structure of A Ras/Raf Complex (State 1) (pdb code 8dgs). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of A Ras/Raf Complex (State 1), PDB code: 8dgs:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of A Ras/Raf Complex (State 1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of A Ras/Raf Complex (State 1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn802 b:166.8 occ:1.00 ND1 A:HIS269 2.1 89.6 1.0 SG A:CYS251 2.3 107.3 1.0 SG A:CYS248 2.3 85.8 1.0 SG A:CYS272 2.3 121.9 1.0 CB A:CYS251 2.5 107.3 1.0 CB A:CYS248 2.7 85.8 1.0 CE1 A:HIS269 3.0 89.6 1.0 CG A:HIS269 3.1 89.6 1.0 CB A:HIS269 3.4 89.6 1.0 CB A:CYS272 3.5 121.9 1.0 N A:CYS251 3.5 107.3 1.0 N A:HIS269 3.5 89.6 1.0 CA A:CYS251 3.5 107.3 1.0 CA A:HIS269 4.1 89.6 1.0 NE2 A:HIS269 4.2 89.6 1.0 CD2 A:HIS269 4.2 89.6 1.0 CA A:CYS248 4.2 85.8 1.0 C A:CYS251 4.4 107.3 1.0 C A:PHE268 4.6 97.9 1.0 CA A:PHE268 4.7 97.9 1.0 C A:PHE250 4.7 114.5 1.0 N A:ARG252 4.8 90.7 1.0 CA A:CYS272 4.8 121.9 1.0 C A:CYS248 4.9 85.8 1.0 CD2 A:PHE250 4.9 114.5 1.0 CB A:PHE268 4.9 97.9 1.0 N A:CYS248 5.0 85.8 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of A Ras/Raf Complex (State 1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of A Ras/Raf Complex (State 1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn803 b:161.4 occ:1.00 ND1 A:HIS235 2.0 126.2 1.0 SG A:CYS261 2.3 106.4 1.0 SG A:CYS264 2.3 115.3 1.0 SG A:CYS280 2.4 172.4 1.0 CG A:HIS235 2.8 126.2 1.0 CE1 A:HIS235 3.0 126.2 1.0 CB A:HIS235 3.2 126.2 1.0 CB A:CYS261 3.4 106.4 1.0 CB A:CYS280 3.9 172.4 1.0 CB A:CYS264 3.9 115.3 1.0 CD2 A:HIS235 4.0 126.2 1.0 CB A:THR263 4.0 111.0 1.0 N A:CYS264 4.0 115.3 1.0 NE2 A:HIS235 4.0 126.2 1.0 CA A:HIS235 4.0 126.2 1.0 OG1 A:THR263 4.4 111.0 1.0 CA A:CYS280 4.4 172.4 1.0 CA A:CYS264 4.5 115.3 1.0 CB A:TYR266 4.7 105.0 1.0 CG2 A:THR263 4.8 111.0 1.0 CA A:CYS261 4.8 106.4 1.0 N A:ASN236 4.8 96.1 1.0 CA A:THR263 4.9 111.0 1.0 C A:THR263 4.9 111.0 1.0 C A:HIS235 4.9 126.2 1.0 N A:THR263 5.0 111.0 1.0

M.J.Eck, H.Jeon, E.Park, S.Rawson. Cryo-Em Structure of A Ras/Raf Complex To Be Published.