Zinc in PDB 8d81: Cereblon~DDB1 Bound to Pomalidomide

Zinc Binding Sites:

The binding sites of Zinc atom in the Cereblon~DDB1 Bound to Pomalidomide (pdb code 8d81). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cereblon~DDB1 Bound to Pomalidomide, PDB code: 8d81:

Zinc binding site 1 out of 1 in 8d81

Go back to Zinc Binding Sites List in 8d81
Zinc binding site 1 out of 1 in the Cereblon~DDB1 Bound to Pomalidomide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cereblon~DDB1 Bound to Pomalidomide within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn501

b:0.0
occ:1.00
SG B:CYS394 2.3 0.0 1.0
SG B:CYS391 2.3 0.0 1.0
SG B:CYS326 2.3 0.0 1.0
SG B:CYS323 2.3 0.0 1.0
CB B:CYS394 3.2 0.0 1.0
CB B:CYS391 3.5 0.0 1.0
CB B:CYS326 3.6 0.0 1.0
N B:CYS394 3.6 0.0 1.0
CB B:CYS323 3.6 0.0 1.0
O B:CYS323 3.9 0.0 1.0
CA B:CYS394 4.0 0.0 1.0
N B:CYS326 4.5 0.0 1.0
N B:ALA395 4.5 0.0 1.0
C B:CYS394 4.6 0.0 1.0
CA B:CYS326 4.6 0.0 1.0
N B:ILE393 4.7 0.0 1.0
C B:CYS323 4.7 0.0 1.0
CA B:CYS323 4.8 0.0 1.0
C B:ILE393 4.8 0.0 1.0
CA B:CYS391 4.9 0.0 1.0
CD1 B:ILE398 5.0 0.0 1.0
N B:LYS392 5.0 0.0 1.0

Reference:

E.R.Watson, S.J.Novick, M.E.Matyskiela, P.P.Chamberlain, A.H.De La Pena, J.Y.Zhu, E.Tran, P.R.Griffin, I.E.Wertz, G.C.Lander. Molecular Glue Celmod Compounds Are Allosteric Regulators of Cereblon Conformation Biorxiv 2022.
DOI: 10.1101/2022.07.02.498551
Page generated: Sat Apr 8 08:10:21 2023

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy