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Atomistry » Zinc » PDB 8c8u-8cn6 » 8cgp | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 8c8u-8cn6 » 8cgp » |
Zinc in PDB 8cgp: Insulin Regulated Aminopeptidase (Irap) in Complex with An Allosteric Aryl Sulfonamide InhibitorEnzymatic activity of Insulin Regulated Aminopeptidase (Irap) in Complex with An Allosteric Aryl Sulfonamide Inhibitor
All present enzymatic activity of Insulin Regulated Aminopeptidase (Irap) in Complex with An Allosteric Aryl Sulfonamide Inhibitor:
3.4.11.3; Protein crystallography data
The structure of Insulin Regulated Aminopeptidase (Irap) in Complex with An Allosteric Aryl Sulfonamide Inhibitor, PDB code: 8cgp
was solved by
A.Mpakali,
E.Stratikos,
P.Giastas,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8cgp:
The structure of Insulin Regulated Aminopeptidase (Irap) in Complex with An Allosteric Aryl Sulfonamide Inhibitor also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Insulin Regulated Aminopeptidase (Irap) in Complex with An Allosteric Aryl Sulfonamide Inhibitor
(pdb code 8cgp). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Insulin Regulated Aminopeptidase (Irap) in Complex with An Allosteric Aryl Sulfonamide Inhibitor, PDB code: 8cgp: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 8cgpGo back to Zinc Binding Sites List in 8cgp
Zinc binding site 1 out
of 2 in the Insulin Regulated Aminopeptidase (Irap) in Complex with An Allosteric Aryl Sulfonamide Inhibitor
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 8cgpGo back to Zinc Binding Sites List in 8cgp
Zinc binding site 2 out
of 2 in the Insulin Regulated Aminopeptidase (Irap) in Complex with An Allosteric Aryl Sulfonamide Inhibitor
Mono view Stereo pair view
Reference:
A.Mpakali,
I.Barla,
L.Lu,
K.M.Ramesh,
N.Thomaidis,
L.J.Stern,
P.Giastas,
E.Stratikos.
Mechanisms of Allosteric Inhibition of Insulin-Regulated Aminopeptidase. J.Mol.Biol. 68449 2024.
Page generated: Wed Oct 30 18:44:37 2024
ISSN: ESSN 1089-8638 PubMed: 38244767 DOI: 10.1016/J.JMB.2024.168449 |
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