Zinc in PDB 8c9e: Priestia Megaterium Mupirocin-Sensitive Isoleucyl-Trna Synthetase 1 Complexed with An Isoleucyl-Adenylate Analogue

Enzymatic activity of Priestia Megaterium Mupirocin-Sensitive Isoleucyl-Trna Synthetase 1 Complexed with An Isoleucyl-Adenylate Analogue

All present enzymatic activity of Priestia Megaterium Mupirocin-Sensitive Isoleucyl-Trna Synthetase 1 Complexed with An Isoleucyl-Adenylate Analogue:
6.1.1.5;

Protein crystallography data

The structure of Priestia Megaterium Mupirocin-Sensitive Isoleucyl-Trna Synthetase 1 Complexed with An Isoleucyl-Adenylate Analogue, PDB code: 8c9e was solved by A.Brkic, M.Leibundgut, J.Jablonska, V.Zanki, Z.Car, V.Petrovic Perokovic, N.Ban, I.Gruic-Sovulj, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 48.77 / 2.90
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 127.09, 127.09, 163.22, 90, 90, 120
R / Rfree (%) 24.2 / 26.9

Other elements in 8c9e:

The structure of Priestia Megaterium Mupirocin-Sensitive Isoleucyl-Trna Synthetase 1 Complexed with An Isoleucyl-Adenylate Analogue also contains other interesting chemical elements:

Chlorine (Cl) 4 atoms
Sodium (Na) 3 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Priestia Megaterium Mupirocin-Sensitive Isoleucyl-Trna Synthetase 1 Complexed with An Isoleucyl-Adenylate Analogue (pdb code 8c9e). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Priestia Megaterium Mupirocin-Sensitive Isoleucyl-Trna Synthetase 1 Complexed with An Isoleucyl-Adenylate Analogue, PDB code: 8c9e:

Zinc binding site 1 out of 1 in 8c9e

Go back to Zinc Binding Sites List in 8c9e
Zinc binding site 1 out of 1 in the Priestia Megaterium Mupirocin-Sensitive Isoleucyl-Trna Synthetase 1 Complexed with An Isoleucyl-Adenylate Analogue


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Priestia Megaterium Mupirocin-Sensitive Isoleucyl-Trna Synthetase 1 Complexed with An Isoleucyl-Adenylate Analogue within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1001

b:307.7
occ:1.00
 SG A:CYS890 2.3 270.4 1.0
SG A:CYS910 2.3 255.2 1.0
SG A:CYS907 2.3 332.2 1.0
SG A:CYS887 2.3 270.6 1.0
CB A:CYS910 3.1 257.4 1.0
CB A:CYS887 3.2 252.0 1.0
CB A:CYS890 3.2 270.6 1.0
N A:CYS890 3.6 286.0 1.0
CB A:CYS907 3.6 294.6 1.0
N A:CYS907 3.9 285.4 1.0
CA A:CYS890 4.0 279.6 1.0
N A:CYS910 4.0 257.1 1.0
CA A:CYS910 4.1 259.8 1.0
CA A:CYS907 4.3 284.2 1.0
CB A:ARG889 4.5 276.5 1.0
CA A:CYS887 4.6 255.3 1.0
C A:ARG889 4.7 275.9 1.0
C A:CYS890 4.8 275.8 1.0
C A:CYS907 4.9 284.2 1.0
N A:ARG889 4.9 274.0 1.0
CA A:ARG889 4.9 275.2 1.0
N A:TRP891 5.0 262.2 1.0
C A:LEU906 5.0 258.6 1.0

Reference:

A.Brkic, M.Leibundgut, J.Jablonska, V.Zanki, Z.Car, V.Petrovic Perokovic, N.Ban, I.Gruic-Sovulj. Antibiotic Hyper-Resistance in A Class I Aminoacyl-Trna Synthetase with Altered Active Site Signature Motif To Be Published.
Page generated: Wed Oct 30 18:38:21 2024

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