Zinc in PDB 7zez: Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription Regulation

All present enzymatic activity of Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription Regulation:
5.2.1.8;

The binding sites of Zinc atom in the Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription Regulation (pdb code 7zez). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription Regulation, PDB code: 7zez:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription Regulation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription Regulation within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1701 b:0.0 occ:1.00 ND1 B:HIS1596 2.0 0.0 1.0 SG B:CYS1569 2.3 0.0 1.0 SG B:CYS1599 2.3 0.0 1.0 SG B:CYS1572 2.3 0.0 1.0 CE1 B:HIS1596 3.0 0.0 1.0 HB2 B:HIS1596 3.0 0.0 1.0 CG B:HIS1596 3.1 0.0 1.0 H B:HIS1596 3.2 0.0 1.0 HE1 B:HIS1596 3.2 0.0 1.0 HB3 B:CYS1599 3.3 0.0 1.0 CB B:CYS1569 3.3 0.0 1.0 HB2 B:CYS1569 3.4 0.0 1.0 CB B:CYS1599 3.4 0.0 1.0 HB3 B:CYS1569 3.5 0.0 1.0 CB B:CYS1572 3.5 0.0 1.0 HB3 B:CYS1572 3.5 0.0 1.0 H B:CYS1572 3.5 0.0 1.0 CB B:HIS1596 3.6 0.0 1.0 HB2 B:CYS1599 3.8 0.0 1.0 HB2 B:LYS1574 3.8 0.0 1.0 N B:CYS1572 3.8 0.0 1.0 HE2 B:LYS1574 3.9 0.0 1.0 HB2 B:LEU1571 4.0 0.0 1.0 HZ2 B:LYS1574 4.0 0.0 1.0 HZ3 B:LYS1574 4.0 0.0 1.0 N B:HIS1596 4.0 0.0 1.0 H B:LEU1571 4.1 0.0 1.0 CA B:CYS1572 4.1 0.0 1.0 NE2 B:HIS1596 4.2 0.0 1.0 CD2 B:HIS1596 4.2 0.0 1.0 H B:CYS1599 4.3 0.0 1.0 HB2 B:CYS1572 4.4 0.0 1.0 CA B:HIS1596 4.4 0.0 1.0 NZ B:LYS1574 4.4 0.0 1.0 HB3 B:HIS1596 4.4 0.0 1.0 H B:LYS1574 4.5 0.0 1.0 C B:LEU1571 4.5 0.0 1.0 HG23 B:VAL1595 4.5 0.0 1.0 O B:CYS1572 4.5 0.0 1.0 HA B:VAL1595 4.6 0.0 1.0 C B:CYS1572 4.6 0.0 1.0 HG22 B:VAL1595 4.6 0.0 1.0 HD2 B:PRO1570 4.7 0.0 1.0 CE B:LYS1574 4.7 0.0 1.0 CA B:CYS1599 4.7 0.0 1.0 CA B:CYS1569 4.8 0.0 1.0 N B:CYS1599 4.8 0.0 1.0 CB B:LYS1574 4.9 0.0 1.0 CB B:LEU1571 4.9 0.0 1.0 N B:LEU1571 4.9 0.0 1.0 CA B:LEU1571 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription Regulation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription Regulation within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1702 b:0.0 occ:1.00 SG B:CYS1588 2.3 0.0 1.0 SG B:CYS1621 2.3 0.0 1.0 SG B:CYS1591 2.3 0.0 1.0 SG B:CYS1624 2.3 0.0 1.0 H B:CYS1621 2.9 0.0 1.0 HB2 B:CYS1621 3.2 0.0 1.0 CB B:CYS1588 3.3 0.0 1.0 HB2 B:CYS1588 3.3 0.0 1.0 H B:CYS1591 3.4 0.0 1.0 CB B:CYS1621 3.4 0.0 1.0 HB2 B:CYS1624 3.4 0.0 1.0 CB B:CYS1624 3.4 0.0 1.0 HB3 B:CYS1591 3.4 0.0 1.0 CB B:CYS1591 3.5 0.0 1.0 HB3 B:CYS1588 3.5 0.0 1.0 HB3 B:CYS1624 3.7 0.0 1.0 N B:CYS1621 3.8 0.0 1.0 N B:CYS1591 3.8 0.0 1.0 HB3 B:LYS1590 3.9 0.0 1.0 HA B:THR1620 4.1 0.0 1.0 CA B:CYS1591 4.1 0.0 1.0 HB3 B:ARG1593 4.2 0.0 1.0 H B:LYS1590 4.2 0.0 1.0 CA B:CYS1621 4.2 0.0 1.0 HB3 B:CYS1621 4.2 0.0 1.0 H B:ARG1593 4.3 0.0 1.0 HB2 B:CYS1591 4.4 0.0 1.0 H B:CYS1624 4.5 0.0 1.0 C B:LYS1590 4.7 0.0 1.0 CA B:CYS1588 4.7 0.0 1.0 HG2 B:LYS1590 4.7 0.0 1.0 CA B:CYS1624 4.8 0.0 1.0 C B:CYS1591 4.8 0.0 1.0 HA B:CYS1621 4.8 0.0 1.0 C B:THR1620 4.9 0.0 1.0 CB B:LYS1590 4.9 0.0 1.0 H B:ASP1592 4.9 0.0 1.0 CA B:THR1620 5.0 0.0 1.0 HA B:CYS1588 5.0 0.0 1.0

M.Blatter, F.Allain. Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription Regulation To Be Published.