Zinc in PDB 7zes: Human SLFN11 Dimer Bound to Ssdna

The structure of Human SLFN11 Dimer Bound to Ssdna also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Zinc atom in the Human SLFN11 Dimer Bound to Ssdna (pdb code 7zes). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Human SLFN11 Dimer Bound to Ssdna, PDB code: 7zes:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Human SLFN11 Dimer Bound to Ssdna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human SLFN11 Dimer Bound to Ssdna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:82.8 occ:1.00 ND1 A:HIS285 2.3 50.0 1.0 SG A:CYS321 2.3 45.1 1.0 SG A:CYS287 2.3 67.3 1.0 SG A:CYS322 2.8 41.2 1.0 CE1 A:HIS285 3.1 50.0 1.0 CG A:HIS285 3.4 50.0 1.0 CB A:CYS321 3.6 45.1 1.0 O A:PRO289 3.7 73.7 1.0 CB A:HIS285 3.9 50.0 1.0 CB A:CYS287 3.9 67.3 1.0 O A:CYS287 4.0 67.3 1.0 CB A:CYS322 4.0 41.2 1.0 N A:CYS287 4.2 67.3 1.0 NE2 A:HIS285 4.3 50.0 1.0 CA A:HIS285 4.3 50.0 1.0 C A:CYS287 4.3 67.3 1.0 C A:CYS321 4.4 45.1 1.0 CA A:CYS287 4.4 67.3 1.0 CD2 A:HIS285 4.5 50.0 1.0 N A:PHE286 4.5 48.7 1.0 N A:CYS322 4.5 41.2 1.0 CA A:CYS321 4.6 45.1 1.0 O A:CYS321 4.6 45.1 1.0 CA A:GLN290 4.8 68.6 1.0 C A:PRO289 4.8 73.7 1.0 C A:HIS285 4.9 50.0 1.0 CA A:CYS322 4.9 41.2 1.0

Zinc binding site 2 out of 2 in the Human SLFN11 Dimer Bound to Ssdna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Human SLFN11 Dimer Bound to Ssdna within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1001 b:82.0 occ:1.00 ND1 B:HIS285 2.1 49.9 1.0 SG B:CYS287 2.3 65.5 1.0 SG B:CYS322 2.3 42.6 1.0 SG B:CYS321 2.3 45.5 1.0 CE1 B:HIS285 2.8 49.9 1.0 CG B:HIS285 3.3 49.9 1.0 CB B:CYS321 3.4 45.5 1.0 CB B:CYS322 3.6 42.6 1.0 CB B:HIS285 3.8 49.9 1.0 CB B:CYS287 3.8 65.5 1.0 C B:CYS321 3.9 45.5 1.0 NE2 B:HIS285 4.0 49.9 1.0 N B:CYS322 4.1 42.6 1.0 CA B:HIS285 4.1 49.9 1.0 O B:CYS321 4.2 45.5 1.0 CD2 B:HIS285 4.2 49.9 1.0 N B:CYS287 4.2 65.5 1.0 CA B:CYS321 4.3 45.5 1.0 N B:PHE286 4.3 48.2 1.0 O B:PRO289 4.3 71.7 1.0 CA B:CYS322 4.4 42.6 1.0 CA B:CYS287 4.5 65.5 1.0 O B:CYS287 4.5 65.5 1.0 C B:CYS287 4.7 65.5 1.0 C B:HIS285 4.7 49.9 1.0 N B:CYS321 5.0 45.5 1.0

F.J.Metzner, S.J.Wenzl, M.Kugler, S.Krebs, K.P.Hopfner, K.Lammens. Mechanistic Understanding of Human SLFN11. Nat Commun V. 13 5464 2022.
ISSN: ESSN 2041-1723
PubMed: 36115853
DOI: 10.1038/S41467-022-33123-0