Zinc in PDB 7zep: Human SLFN11 E209A Dimer

The binding sites of Zinc atom in the Human SLFN11 E209A Dimer (pdb code 7zep). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Human SLFN11 E209A Dimer, PDB code: 7zep:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Human SLFN11 E209A Dimer


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human SLFN11 E209A Dimer within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:92.4 occ:1.00 SG A:CYS321 2.3 56.9 1.0 ND1 A:HIS285 2.3 64.1 1.0 SG A:CYS287 2.3 77.7 1.0 SG A:CYS322 2.8 53.2 1.0 CE1 A:HIS285 3.1 64.1 1.0 CG A:HIS285 3.4 64.1 1.0 O A:PRO289 3.6 83.6 1.0 CB A:CYS321 3.6 56.9 1.0 CB A:HIS285 3.8 64.1 1.0 CB A:CYS322 3.9 53.2 1.0 CB A:CYS287 3.9 77.7 1.0 N A:CYS287 4.2 77.7 1.0 O A:CYS287 4.2 77.7 1.0 CA A:HIS285 4.3 64.1 1.0 C A:CYS321 4.3 56.9 1.0 NE2 A:HIS285 4.3 64.1 1.0 CA A:CYS287 4.4 77.7 1.0 N A:PHE286 4.4 64.0 1.0 N A:CYS322 4.4 53.2 1.0 CD2 A:HIS285 4.5 64.1 1.0 O A:CYS321 4.5 56.9 1.0 C A:CYS287 4.5 77.7 1.0 CA A:CYS321 4.5 56.9 1.0 CA A:GLN290 4.6 76.2 1.0 C A:PRO289 4.7 83.6 1.0 CA A:CYS322 4.8 53.2 1.0 C A:HIS285 4.8 64.1 1.0

Zinc binding site 2 out of 2 in the Human SLFN11 E209A Dimer


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Human SLFN11 E209A Dimer within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1001 b:91.5 occ:1.00 ND1 B:HIS285 2.1 65.8 1.0 SG B:CYS321 2.3 56.6 1.0 SG B:CYS322 2.3 53.6 1.0 SG B:CYS287 2.3 80.2 1.0 CE1 B:HIS285 2.7 65.8 1.0 CG B:HIS285 3.3 65.8 1.0 CB B:CYS321 3.3 56.6 1.0 CB B:CYS322 3.6 53.6 1.0 CB B:CYS287 3.8 80.2 1.0 NE2 B:HIS285 3.9 65.8 1.0 CB B:HIS285 4.0 65.8 1.0 C B:CYS321 4.0 56.6 1.0 O B:PRO289 4.1 87.4 1.0 N B:CYS322 4.1 53.6 1.0 N B:CYS287 4.2 80.2 1.0 O B:CYS321 4.2 56.6 1.0 CA B:CYS321 4.3 56.6 1.0 CD2 B:HIS285 4.3 65.8 1.0 N B:PHE286 4.3 63.6 1.0 CA B:HIS285 4.3 65.8 1.0 O B:CYS287 4.4 80.2 1.0 CA B:CYS287 4.4 80.2 1.0 CA B:CYS322 4.5 53.6 1.0 C B:CYS287 4.7 80.2 1.0 C B:HIS285 4.8 65.8 1.0 N B:CYS321 5.0 56.6 1.0

F.J.Metzner, S.J.Wenzl, M.Kugler, S.Krebs, K.P.Hopfner, K.Lammens. Mechanistic Understanding of Human SLFN11. Nat Commun V. 13 5464 2022.
ISSN: ESSN 2041-1723
PubMed: 36115853
DOI: 10.1038/S41467-022-33123-0