Zinc in PDB 7zbz: CAND1 Delhairpin-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked
Zinc Binding Sites:
The binding sites of Zinc atom in the CAND1 Delhairpin-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked
(pdb code 7zbz). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the
CAND1 Delhairpin-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked, PDB code: 7zbz:
Jump to Zinc binding site number:
1;
2;
3;
Zinc binding site 1 out
of 3 in 7zbz
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Zinc Binding Sites List in 7zbz
Zinc binding site 1 out
of 3 in the CAND1 Delhairpin-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked
![](/pictures/ZN/pdb/zb/7zbz-ZN-sphere_01.jpg) Mono view
![](/pictures/ZN/pdb/zb/7zbz-ZN-sphere_01_stereo.jpg) Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of CAND1 Delhairpin-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
R:Zn201
b:84.9
occ:1.00
|
ND1
|
R:HIS80
|
2.0
|
69.9
|
1.0
|
SG
|
R:CYS45
|
2.3
|
81.8
|
1.0
|
SG
|
R:CYS42
|
2.3
|
79.0
|
1.0
|
SG
|
R:CYS83
|
2.3
|
68.2
|
1.0
|
CE1
|
R:HIS80
|
2.8
|
69.9
|
1.0
|
CB
|
R:CYS42
|
2.8
|
79.0
|
1.0
|
CG
|
R:HIS80
|
3.2
|
69.9
|
1.0
|
CB
|
R:CYS83
|
3.6
|
68.2
|
1.0
|
CB
|
R:HIS80
|
3.6
|
69.9
|
1.0
|
CB
|
R:CYS45
|
3.7
|
81.8
|
1.0
|
N
|
R:CYS45
|
4.0
|
81.8
|
1.0
|
NE2
|
R:HIS80
|
4.0
|
69.9
|
1.0
|
O
|
R:CYS45
|
4.1
|
81.8
|
1.0
|
CD2
|
R:HIS80
|
4.2
|
69.9
|
1.0
|
CA
|
R:CYS45
|
4.3
|
81.8
|
1.0
|
N
|
R:HIS80
|
4.3
|
69.9
|
1.0
|
CA
|
R:CYS42
|
4.3
|
79.0
|
1.0
|
CA
|
R:HIS80
|
4.6
|
69.9
|
1.0
|
C
|
R:CYS45
|
4.7
|
81.8
|
1.0
|
SG
|
R:CYS53
|
4.9
|
89.6
|
1.0
|
C
|
R:CYS42
|
4.9
|
79.0
|
1.0
|
CA
|
R:CYS83
|
5.0
|
68.2
|
1.0
|
CB
|
R:ILE44
|
5.0
|
75.2
|
1.0
|
|
Zinc binding site 2 out
of 3 in 7zbz
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Zinc Binding Sites List in 7zbz
Zinc binding site 2 out
of 3 in the CAND1 Delhairpin-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked
![](/pictures/ZN/pdb/zb/7zbz-ZN-sphere_02.jpg) Mono view
![](/pictures/ZN/pdb/zb/7zbz-ZN-sphere_02_stereo.jpg) Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of CAND1 Delhairpin-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
R:Zn202
b:61.8
occ:1.00
|
OD2
|
R:ASP97
|
2.0
|
61.1
|
1.0
|
ND1
|
R:HIS77
|
2.0
|
51.9
|
1.0
|
SG
|
R:CYS75
|
2.3
|
50.8
|
1.0
|
SG
|
R:CYS94
|
2.3
|
59.1
|
1.0
|
CG
|
R:ASP97
|
2.9
|
61.1
|
1.0
|
CE1
|
R:HIS77
|
2.9
|
51.9
|
1.0
|
CG
|
R:HIS77
|
3.1
|
51.9
|
1.0
|
OD1
|
R:ASP97
|
3.3
|
61.1
|
1.0
|
CB
|
R:CYS94
|
3.3
|
59.1
|
1.0
|
CB
|
R:CYS75
|
3.3
|
50.8
|
1.0
|
CB
|
R:HIS77
|
3.5
|
51.9
|
1.0
|
NE2
|
R:HIS77
|
4.1
|
51.9
|
1.0
|
CB
|
R:ASP97
|
4.1
|
61.1
|
1.0
|
CD2
|
R:HIS77
|
4.2
|
51.9
|
1.0
|
N
|
R:ASP97
|
4.3
|
61.1
|
1.0
|
O
|
R:CYS75
|
4.6
|
50.8
|
1.0
|
CA
|
R:CYS75
|
4.6
|
50.8
|
1.0
|
CB
|
R:LEU96
|
4.7
|
58.0
|
1.0
|
C
|
R:LEU96
|
4.7
|
58.0
|
1.0
|
CA
|
R:ASP97
|
4.8
|
61.1
|
1.0
|
CA
|
R:CYS94
|
4.8
|
59.1
|
1.0
|
C
|
R:CYS75
|
4.8
|
50.8
|
1.0
|
CZ3
|
R:TRP101
|
4.8
|
53.9
|
1.0
|
CA
|
R:HIS77
|
4.8
|
51.9
|
1.0
|
N
|
R:LEU96
|
4.8
|
58.0
|
1.0
|
N
|
R:HIS77
|
4.9
|
51.9
|
1.0
|
CA
|
R:LEU96
|
5.0
|
58.0
|
1.0
|
|
Zinc binding site 3 out
of 3 in 7zbz
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Zinc Binding Sites List in 7zbz
Zinc binding site 3 out
of 3 in the CAND1 Delhairpin-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked
![](/pictures/ZN/pdb/zb/7zbz-ZN-sphere_03.jpg) Mono view
![](/pictures/ZN/pdb/zb/7zbz-ZN-sphere_03_stereo.jpg) Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of CAND1 Delhairpin-Scf-SKP2 CAND1 Partly Engaged Scf Partly Rocked within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
R:Zn203
b:87.8
occ:1.00
|
ND1
|
R:HIS82
|
2.0
|
72.1
|
1.0
|
SG
|
R:CYS68
|
2.3
|
82.0
|
1.0
|
SG
|
R:CYS56
|
2.3
|
92.4
|
1.0
|
SG
|
R:CYS53
|
2.3
|
89.6
|
1.0
|
CB
|
R:CYS53
|
2.9
|
89.6
|
1.0
|
CE1
|
R:HIS82
|
2.9
|
72.1
|
1.0
|
CG
|
R:HIS82
|
3.1
|
72.1
|
1.0
|
CB
|
R:HIS82
|
3.5
|
72.1
|
1.0
|
CB
|
R:CYS68
|
3.6
|
82.0
|
1.0
|
N
|
R:CYS53
|
3.6
|
89.6
|
1.0
|
CB
|
R:CYS56
|
3.8
|
92.4
|
1.0
|
CA
|
R:CYS53
|
3.9
|
89.6
|
1.0
|
NE2
|
R:HIS82
|
4.1
|
72.1
|
1.0
|
CD2
|
R:HIS82
|
4.2
|
72.1
|
1.0
|
CA
|
R:CYS68
|
4.3
|
82.0
|
1.0
|
CA
|
R:HIS82
|
4.8
|
72.1
|
1.0
|
C
|
R:LEU52
|
4.8
|
88.0
|
1.0
|
N
|
R:HIS82
|
4.8
|
72.1
|
1.0
|
CA
|
R:CYS56
|
5.0
|
92.4
|
1.0
|
|
Reference:
K.Baek,
D.C.Scott,
L.T.Henneberg,
M.T.King,
M.Mann,
B.A.Schulman.
Systemwide Disassembly and Assembly of Scf Ubiquitin Ligase Complexes. Cell 2023.
ISSN: ISSN 1097-4172
PubMed: 37028429
DOI: 10.1016/J.CELL.2023.02.035
Page generated: Wed Apr 26 00:31:13 2023
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