Zinc in PDB 7yeg: Sars-Cov-2 Spike (6P) in Complex with 3 R1-32 Fabs and 3 ACE2

All present enzymatic activity of Sars-Cov-2 Spike (6P) in Complex with 3 R1-32 Fabs and 3 ACE2:
3.4.17.23;

The binding sites of Zinc atom in the Sars-Cov-2 Spike (6P) in Complex with 3 R1-32 Fabs and 3 ACE2 (pdb code 7yeg). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Sars-Cov-2 Spike (6P) in Complex with 3 R1-32 Fabs and 3 ACE2, PDB code: 7yeg:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Sars-Cov-2 Spike (6P) in Complex with 3 R1-32 Fabs and 3 ACE2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sars-Cov-2 Spike (6P) in Complex with 3 R1-32 Fabs and 3 ACE2 within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn901 b:458.5 occ:1.00 NE2 E:HIS378 2.2 489.4 1.0 OE1 E:GLU402 2.6 514.4 1.0 OE2 E:GLU375 2.6 463.9 1.0 CE1 E:HIS378 3.1 489.4 1.0 CD2 E:HIS378 3.2 489.4 1.0 NE2 E:HIS374 3.2 471.3 1.0 CD2 E:HIS374 3.5 471.3 1.0 CD E:GLU402 3.7 514.4 1.0 CD E:GLU375 3.9 463.9 1.0 OE2 E:GLU402 4.2 514.4 1.0 CE1 E:HIS374 4.2 471.3 1.0 ND1 E:HIS378 4.3 489.4 1.0 CG E:HIS378 4.3 489.4 1.0 CG E:GLU375 4.6 463.9 1.0 CG E:HIS374 4.7 471.3 1.0 OE1 E:GLU375 4.7 463.9 1.0 CG E:GLU402 5.0 514.4 1.0

Zinc binding site 2 out of 3 in the Sars-Cov-2 Spike (6P) in Complex with 3 R1-32 Fabs and 3 ACE2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sars-Cov-2 Spike (6P) in Complex with 3 R1-32 Fabs and 3 ACE2 within 5.0Å range: probe atom residue distance (Å) B Occ J:Zn901 b:472.2 occ:1.00 NE2 J:HIS374 2.0 515.9 1.0 OE1 J:GLU402 2.3 526.3 1.0 CE1 J:HIS374 2.5 515.9 1.0 NE2 J:HIS378 2.6 548.6 1.0 CD J:GLU402 3.0 526.3 1.0 OE2 J:GLU402 3.2 526.3 1.0 CD2 J:HIS374 3.2 515.9 1.0 CD2 J:HIS378 3.3 548.6 1.0 CE1 J:HIS378 3.6 548.6 1.0 ND1 J:HIS374 3.7 515.9 1.0 CG J:HIS374 4.0 515.9 1.0 CG J:GLU402 4.4 526.3 1.0 CG J:HIS378 4.4 548.6 1.0 ND1 J:HIS378 4.5 548.6 1.0

Zinc binding site 3 out of 3 in the Sars-Cov-2 Spike (6P) in Complex with 3 R1-32 Fabs and 3 ACE2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Sars-Cov-2 Spike (6P) in Complex with 3 R1-32 Fabs and 3 ACE2 within 5.0Å range: probe atom residue distance (Å) B Occ M:Zn901 b:546.2 occ:1.00 NE2 M:HIS374 2.0 561.3 1.0 NE2 M:HIS378 2.2 562.3 1.0 OE1 M:GLU402 2.2 574.6 1.0 CE1 M:HIS374 3.0 561.3 1.0 CD2 M:HIS374 3.0 561.3 1.0 CE1 M:HIS378 3.0 562.3 1.0 CD2 M:HIS378 3.2 562.3 1.0 CD M:GLU402 3.4 574.6 1.0 ND1 M:HIS374 4.1 561.3 1.0 CG M:HIS374 4.1 561.3 1.0 OE2 M:GLU402 4.1 574.6 1.0 ND1 M:HIS378 4.2 562.3 1.0 CG M:HIS378 4.3 562.3 1.0 CG M:GLU402 4.4 574.6 1.0

B.Liu, X.Gao, X.Chen, J.He, L.Chen, X.Xiong. Sars-Cov-2 Spike(6P)in Complex with 3 R1-32 Fabs and 3 ACE2 To Be Published.