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Zinc in PDB 7y5n: Structure of 1:1 Papp-A.Prombp Complex(Half Map)

Enzymatic activity of Structure of 1:1 Papp-A.Prombp Complex(Half Map)

All present enzymatic activity of Structure of 1:1 Papp-A.Prombp Complex(Half Map):
3.4.24.79;

Other elements in 7y5n:

The structure of Structure of 1:1 Papp-A.Prombp Complex(Half Map) also contains other interesting chemical elements:

Calcium (Ca) 7 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of 1:1 Papp-A.Prombp Complex(Half Map) (pdb code 7y5n). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of 1:1 Papp-A.Prombp Complex(Half Map), PDB code: 7y5n:

Zinc binding site 1 out of 1 in 7y5n

Go back to Zinc Binding Sites List in 7y5n
Zinc binding site 1 out of 1 in the Structure of 1:1 Papp-A.Prombp Complex(Half Map)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of 1:1 Papp-A.Prombp Complex(Half Map) within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn1608

b:23.5
occ:1.00
CE1 C:HIS492 1.8 26.3 1.0
NE2 C:HIS482 2.3 20.7 1.0
NE2 C:HIS486 2.3 36.6 1.0
NE2 C:HIS492 2.3 26.3 1.0
CD2 C:HIS486 2.8 36.6 1.0
ND1 C:HIS492 3.0 26.3 1.0
CD2 C:HIS482 3.1 20.7 1.0
CD1 C:LEU445 3.1 61.1 1.0
CE1 C:HIS482 3.4 20.7 1.0
CE1 C:HIS486 3.5 36.6 1.0
CD2 C:HIS492 3.6 26.3 1.0
CG C:HIS492 3.9 26.3 1.0
CE1 C:TYR558 4.1 25.9 1.0
CG C:HIS486 4.1 36.6 1.0
OH C:TYR558 4.3 25.9 1.0
OE2 C:GLU483 4.3 20.0 1.0
CG C:HIS482 4.3 20.7 1.0
ND1 C:HIS486 4.4 36.6 1.0
ND1 C:HIS482 4.4 20.7 1.0
CG C:LEU445 4.5 61.1 1.0
CZ C:TYR558 4.7 25.9 1.0
CD2 C:LEU445 5.0 61.1 1.0

Reference:

Q.Zhong, H.Chu, G.Wang, C.Zhang, R.Li, F.Guo, X.Meng, X.Lei, Y.Zhou, R.Ren, L.Tao, N.Li, N.Gao, Y.Wei, J.Qiao, J.Hang. Structural Insights Into the Covalent Regulation of Papp-A Activity By Prombp and STC2. Cell Discov V. 8 137 2022.
ISSN: ESSN 2056-5968
PubMed: 36550107
DOI: 10.1038/S41421-022-00502-2
Page generated: Wed Oct 30 15:33:47 2024

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