Zinc in PDB 7wwp: Crystal Structure of Human NPL4

The structure of Crystal Structure of Human NPL4, PDB code: 7wwp was solved by T.Q.Nguyen, L.T.M.Le, D.H.Kim, K.S.Ko, H.T.Lee, Y.T.K.Nguyen, H.S.Kim, B.W.Han, W.Kang, J.K.Yang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.44 / 2.99
Space group	P 64 2 2
Cell size a, b, c (Å), α, β, γ (°)	136.325, 136.325, 126.875, 90, 90, 120
R / Rfree (%)	23.1 / 29.1

The binding sites of Zinc atom in the Crystal Structure of Human NPL4 (pdb code 7wwp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human NPL4, PDB code: 7wwp:

Zinc binding site 1 out of 1 in the Crystal Structure of Human NPL4


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human NPL4 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn901 b:106.8 occ:1.00 NE2 A:HIS132 2.1 118.9 1.0 SG A:CYS138 2.3 102.2 1.0 SG A:CYS141 2.3 104.7 1.0 SG A:CYS130 2.3 121.8 1.0 CE1 A:HIS132 2.8 122.6 1.0 CD2 A:HIS132 3.3 116.1 1.0 CB A:CYS138 3.4 106.3 1.0 CB A:CYS141 3.5 97.6 1.0 CB A:CYS130 3.7 121.0 1.0 N A:CYS138 3.7 105.0 1.0 N A:CYS141 3.9 101.1 1.0 CA A:CYS138 4.0 105.2 1.0 ND1 A:HIS132 4.0 122.3 1.0 O A:CYS138 4.2 102.8 1.0 CG A:HIS132 4.3 119.2 1.0 CA A:CYS141 4.3 102.5 1.0 C A:CYS138 4.3 101.6 1.0 CA A:CYS130 4.4 120.6 1.0 C A:HIS140 4.4 102.5 1.0 C A:LYS137 4.4 106.0 1.0 CB A:HIS140 4.4 109.2 1.0 CG A:ARG125 4.6 110.0 1.0 N A:HIS140 4.7 103.9 1.0 CD A:ARG125 4.7 115.8 1.0 CA A:HIS140 4.7 103.3 1.0 CA A:LYS137 4.8 109.4 1.0 N A:ARG131 4.9 116.6 1.0

T.Q.Nguyen, L.T.My Le, D.H.Kim, K.S.Ko, H.T.Lee, Y.T.Kim Nguyen, H.S.Kim, B.W.Han, W.Kang, J.K.Yang. Structural Basis For the Interaction Between Human NPL4 and NPL4-Binding Motif of Human UFD1. Structure V. 30 1530 2022.
ISSN: ISSN 0969-2126
PubMed: 36087575
DOI: 10.1016/J.STR.2022.08.005