Zinc in PDB 7ww2: Structure of An Isocytosine Specific Deaminase Vcz

All present enzymatic activity of Structure of An Isocytosine Specific Deaminase Vcz:
3.5.4.32;

The structure of Structure of An Isocytosine Specific Deaminase Vcz, PDB code: 7ww2 was solved by X.J.Li, B.X.Wu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.76 / 2.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	68.442, 107.523, 120.506, 90, 90, 90
R / Rfree (%)	18.2 / 24.2

The binding sites of Zinc atom in the Structure of An Isocytosine Specific Deaminase Vcz (pdb code 7ww2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of An Isocytosine Specific Deaminase Vcz, PDB code: 7ww2:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of An Isocytosine Specific Deaminase Vcz


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of An Isocytosine Specific Deaminase Vcz within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:21.5 occ:1.00 NE2 A:HIS95 2.2 19.6 1.0 NE2 A:HIS93 2.3 21.2 1.0 NE2 A:HIS259 2.3 21.3 1.0 OD1 A:ASP347 2.5 19.2 1.0 CD2 A:HIS95 2.9 18.8 1.0 CD2 A:HIS259 3.1 21.7 1.0 CD2 A:HIS93 3.2 19.9 1.0 CE1 A:HIS93 3.2 21.6 1.0 CG A:ASP347 3.2 17.4 1.0 CE1 A:HIS259 3.3 28.6 1.0 OD2 A:ASP347 3.3 18.1 1.0 CE1 A:HIS95 3.4 20.5 1.0 NE2 A:HIS296 3.8 22.1 1.0 CG A:HIS95 4.1 19.8 1.0 ND1 A:HIS93 4.3 22.4 1.0 ND1 A:HIS95 4.3 20.6 1.0 CG A:HIS93 4.3 23.2 1.0 CG A:HIS259 4.3 26.1 1.0 ND1 A:HIS259 4.4 25.5 1.0 CB A:ASP347 4.6 16.9 1.0 CE1 A:HIS296 4.7 20.9 1.0 CD2 A:HIS296 4.7 23.4 1.0 N A:GLY348 4.8 20.3 1.0 CA A:ASP347 5.0 17.7 1.0

Zinc binding site 2 out of 2 in the Structure of An Isocytosine Specific Deaminase Vcz


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of An Isocytosine Specific Deaminase Vcz within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn501 b:23.9 occ:1.00 O B:HOH603 2.1 22.3 1.0 NE2 B:HIS259 2.3 29.3 1.0 NE2 B:HIS93 2.3 18.9 1.0 NE2 B:HIS95 2.3 27.8 1.0 OD1 B:ASP347 2.3 21.5 1.0 CD2 B:HIS95 3.0 23.9 1.0 CE1 B:HIS259 3.1 30.1 1.0 CD2 B:HIS93 3.1 19.2 1.0 CE1 B:HIS95 3.1 23.8 1.0 CE1 B:HIS93 3.3 20.8 1.0 CG B:ASP347 3.3 23.6 1.0 CD2 B:HIS259 3.4 28.4 1.0 OD2 B:ASP347 3.5 25.6 1.0 NE2 B:HIS296 4.0 22.9 1.0 ND1 B:HIS95 4.0 24.5 1.0 CG B:HIS95 4.0 20.5 1.0 CG B:HIS93 4.2 20.0 1.0 ND1 B:HIS259 4.3 28.8 1.0 ND1 B:HIS93 4.3 21.0 1.0 CG B:HIS259 4.4 27.8 1.0 CB B:ASP347 4.6 22.1 1.0 CE1 B:HIS296 4.7 22.3 1.0 N B:GLY348 4.8 21.5 1.0 CD2 B:HIS296 4.9 25.0 1.0 ND1 B:HIS153 5.0 26.9 1.0

X.J.Li, B.X.Wu. Structure of An Isocytosine Specific Deaminase Vcz To Be Published.