Zinc in PDB 7wtz: Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B2

The binding sites of Zinc atom in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B2 (pdb code 7wtz). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B2, PDB code: 7wtz:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B2 within 5.0Å range: probe atom residue distance (Å) B Occ f:Zn200 b:57.6 occ:1.00 N f:LYS143 2.2 32.9 1.0 N f:CYS145 2.2 36.2 1.0 N f:CYS144 2.2 33.1 1.0 C f:LYS143 2.5 32.9 1.0 O f:CYS141 2.7 41.2 1.0 CA f:LYS143 2.8 32.9 1.0 C f:GLY142 2.8 36.5 1.0 C f:CYS144 3.0 33.1 1.0 CA f:CYS144 3.1 33.1 1.0 CA f:CYS145 3.2 36.2 1.0 O f:LYS143 3.2 32.9 1.0 C f:CYS141 3.3 41.2 1.0 CA f:GLY142 3.3 36.5 1.0 N f:GLY142 3.5 36.5 1.0 O f:GLY142 3.6 36.5 1.0 SG f:CYS145 3.6 36.2 1.0 CB f:CYS145 3.9 36.2 1.0 SG f:CYS141 4.0 41.2 1.0 CB f:LYS143 4.1 32.9 1.0 O f:CYS144 4.2 33.1 1.0 OH f:TYR140 4.3 55.5 1.0 CB f:CYS141 4.4 41.2 1.0 CB f:CYS144 4.4 33.1 1.0 CA f:CYS141 4.4 41.2 1.0 C f:CYS145 4.5 36.2 1.0 CZ f:TYR140 4.6 55.5 1.0 N f:LEU146 4.7 41.0 1.0 SG f:CYS144 4.8 33.1 1.0 CE1 f:TYR140 4.9 55.5 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B2 within 5.0Å range: probe atom residue distance (Å) B Occ y:Zn500 b:42.3 occ:1.00 SG y:CYS273 2.3 6.2 1.0 SG y:CYS270 2.3 6.2 1.0 SG y:CYS288 2.3 6.2 1.0 SG y:CYS285 2.5 9.4 1.0 CB y:CYS270 3.3 6.2 1.0 CB y:CYS288 3.4 6.2 1.0 CB y:CYS273 3.5 6.2 1.0 N y:CYS288 3.8 6.2 1.0 CB y:CYS285 3.8 9.4 1.0 N y:CYS273 3.9 6.2 1.0 CA y:CYS288 4.1 6.2 1.0 CG2 y:THR292 4.2 7.4 1.0 CA y:CYS273 4.2 6.2 1.0 N y:GLY289 4.7 6.2 1.0 C y:CYS288 4.7 6.2 1.0 CB y:HIS287 4.7 6.2 1.0 CA y:CYS270 4.7 6.2 1.0 C y:GLY272 4.8 6.2 1.0 C y:HIS287 4.9 6.2 1.0 CA y:GLY272 5.0 6.2 1.0 N y:GLY272 5.0 6.2 1.0

J.Cheng, B.Lau, M.Thoms, M.Ameismeier, O.Berninghausen, E.Hurt, R.Beckmann. The Nucleoplasmic Phase of Pre-40S Formation Prior to Nuclear Export. Nucleic Acids Res. V. 50 11924 2022.
ISSN: ESSN 1362-4962
PubMed: 36321656
DOI: 10.1093/NAR/GKAC961