Zinc in PDB 7wtx: Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B1

The binding sites of Zinc atom in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B1 (pdb code 7wtx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B1, PDB code: 7wtx:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B1 within 5.0Å range: probe atom residue distance (Å) B Occ f:Zn200 b:34.5 occ:1.00 O f:CYS141 2.4 26.2 1.0 SG f:CYS145 2.5 27.9 1.0 O2' 2:A1291 2.5 40.8 1.0 C f:CYS141 3.4 26.2 1.0 CB f:CYS145 3.6 27.9 1.0 CA f:GLY142 3.7 23.2 1.0 CA f:CYS145 3.8 27.9 1.0 N f:CYS145 3.9 27.9 1.0 N f:GLY142 3.9 23.2 1.0 C2' 2:A1291 3.9 40.8 1.0 C f:GLY142 4.0 23.2 1.0 N f:LYS143 4.2 26.4 1.0 CA f:CYS141 4.5 26.2 1.0 O f:GLY142 4.5 23.2 1.0 C1' 2:A1291 4.5 40.8 1.0 CD2 f:TYR140 4.6 31.6 1.0 CB f:CYS141 4.6 26.2 1.0 O3' 2:A1291 4.7 40.8 1.0 C3' 2:A1291 4.7 40.8 1.0 N f:CYS141 4.8 26.2 1.0 N f:CYS144 4.8 26.4 1.0 C4' 2:A1291 4.9 40.8 1.0 C f:LYS143 4.9 26.4 1.0 C f:CYS144 4.9 26.4 1.0 SG f:CYS141 4.9 26.2 1.0 CE2 f:TYR140 5.0 31.6 1.0 CA f:LYS143 5.0 26.4 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- B1 within 5.0Å range: probe atom residue distance (Å) B Occ y:Zn500 b:20.5 occ:1.00 SG y:CYS285 2.3 8.6 1.0 SG y:CYS270 2.3 8.1 1.0 SG y:CYS288 2.3 7.5 1.0 SG y:CYS273 2.5 7.5 1.0 CB y:CYS285 2.9 8.6 1.0 CB y:CYS270 3.0 8.1 1.0 CB y:CYS288 3.6 7.5 1.0 CB y:CYS273 3.8 7.5 1.0 N y:CYS288 4.0 7.5 1.0 N y:CYS273 4.1 7.5 1.0 CG2 y:THR292 4.3 4.4 1.0 CA y:CYS288 4.3 7.5 1.0 CA y:CYS285 4.4 8.6 1.0 CA y:CYS273 4.5 7.5 1.0 CA y:CYS270 4.5 8.1 1.0 CB y:HIS287 4.8 7.8 1.0 N y:GLY289 4.9 6.5 1.0 N y:HIS287 5.0 7.8 1.0

J.Cheng, B.Lau, M.Thoms, M.Ameismeier, O.Berninghausen, E.Hurt, R.Beckmann. The Nucleoplasmic Phase of Pre-40S Formation Prior to Nuclear Export. Nucleic Acids Res. V. 50 11924 2022.
ISSN: ESSN 1362-4962
PubMed: 36321656
DOI: 10.1093/NAR/GKAC961