Zinc in PDB 7wtw: Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- A3

The binding sites of Zinc atom in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- A3 (pdb code 7wtw). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- A3, PDB code: 7wtw:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- A3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- A3 within 5.0Å range: probe atom residue distance (Å) B Occ f:Zn500 b:28.1 occ:1.00 O f:VAL130 2.3 25.8 1.0 N f:MET132 2.9 27.7 1.0 N f:CYS121 3.0 26.8 1.0 CB f:MET132 3.0 27.7 1.0 CA f:MET132 3.0 27.7 1.0 C f:PHE131 3.1 29.9 1.0 C f:VAL130 3.4 25.8 1.0 O f:ARG119 3.4 29.5 1.0 CB f:CYS121 3.5 26.8 1.0 O f:PHE131 3.6 29.9 1.0 C f:GLU120 3.6 28.1 1.0 CA f:CYS121 3.7 26.8 1.0 CA f:PHE131 3.7 29.9 1.0 CA f:GLU120 3.8 28.1 1.0 SD f:MET132 3.8 27.7 1.0 CG f:MET132 3.8 27.7 1.0 N f:PHE131 4.0 29.9 1.0 C f:ARG119 4.1 29.5 1.0 N f:GLU120 4.3 28.1 1.0 SG f:CYS141 4.4 27.3 1.0 C f:MET132 4.6 27.7 1.0 O f:GLU120 4.6 28.1 1.0 CA f:VAL130 4.6 25.8 1.0 CB f:VAL130 4.7 25.8 1.0 CG1 f:VAL130 4.9 25.8 1.0 SG f:CYS121 5.0 26.8 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- A3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- A3 within 5.0Å range: probe atom residue distance (Å) B Occ y:Zn500 b:31.2 occ:1.00 SG y:CYS270 2.3 23.0 1.0 SG y:CYS273 2.3 25.1 1.0 SG y:CYS285 2.3 23.4 1.0 SG y:CYS288 2.3 24.2 1.0 CB y:CYS270 3.1 23.0 1.0 CB y:CYS285 3.2 23.4 1.0 CB y:CYS288 3.4 24.2 1.0 CB y:CYS273 3.5 25.1 1.0 N y:CYS288 3.8 24.2 1.0 N y:CYS273 3.8 25.1 1.0 CG2 y:THR292 4.1 20.9 1.0 CA y:CYS273 4.1 25.1 1.0 CA y:CYS288 4.2 24.2 1.0 CA y:CYS270 4.6 23.0 1.0 CA y:CYS285 4.6 23.4 1.0 N y:GLY289 4.6 24.3 1.0 C y:CYS273 4.6 25.1 1.0 N y:HIS287 4.8 25.8 1.0 C y:GLY272 4.8 21.9 1.0 N y:PHE274 4.8 24.4 1.0 C y:HIS287 4.9 25.8 1.0 C y:CYS288 4.9 24.2 1.0 N y:SER286 4.9 24.7 1.0 N y:GLY272 5.0 21.9 1.0 CB y:HIS287 5.0 25.8 1.0

J.Cheng, B.Lau, M.Thoms, M.Ameismeier, O.Berninghausen, E.Hurt, R.Beckmann. The Nucleoplasmic Phase of Pre-40S Formation Prior to Nuclear Export. Nucleic Acids Res. V. 50 11924 2022.
ISSN: ESSN 1362-4962
PubMed: 36321656
DOI: 10.1093/NAR/GKAC961