Zinc in PDB 7wtt: Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- A1 (with CK1)

All present enzymatic activity of Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- A1 (with CK1):
2.7.11.1;

The binding sites of Zinc atom in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- A1 (with CK1) (pdb code 7wtt). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- A1 (with CK1), PDB code: 7wtt:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- A1 (with CK1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of A Human Pre-40S Ribosomal Subunit - State RRP12- A1 (with CK1) within 5.0Å range: probe atom residue distance (Å) B Occ f:Zn500 b:23.9 occ:1.00 SG f:CYS141 2.3 19.9 1.0 SG f:CYS144 2.3 18.4 1.0 SG f:CYS126 2.3 19.9 1.0 SG f:CYS121 2.3 17.5 1.0 CB f:CYS126 2.6 19.9 1.0 CB f:CYS144 3.4 18.4 1.0 CB f:CYS141 3.4 19.9 1.0 CB f:CYS121 3.6 17.5 1.0 N f:CYS144 3.8 18.4 1.0 CB f:SER123 3.9 19.2 1.0 CA f:CYS126 4.1 19.9 1.0 CA f:CYS144 4.2 18.4 1.0 CG1 f:VAL130 4.6 19.9 1.0 OG f:SER123 4.6 19.2 1.0 N f:CYS126 4.6 19.9 1.0 CA f:CYS141 4.8 19.9 1.0 CD1 f:LEU146 4.8 18.8 1.0 C f:CYS144 4.8 18.4 1.0 CB f:LYS143 4.9 20.8 1.0 C f:LYS143 4.9 20.8 1.0 C f:CYS126 4.9 19.9 1.0 N f:CYS145 4.9 19.0 1.0 CA f:CYS121 5.0 17.5 1.0

J.Cheng, B.Lau, M.Thoms, M.Ameismeier, O.Berninghausen, E.Hurt, R.Beckmann. The Nucleoplasmic Phase of Pre-40S Formation Prior to Nuclear Export. Nucleic Acids Res. V. 50 11924 2022.
ISSN: ESSN 1362-4962
PubMed: 36321656
DOI: 10.1093/NAR/GKAC961