Zinc in PDB 7wjl: Crystal Structure of S. Cerevisiae HOS3

The structure of Crystal Structure of S. Cerevisiae HOS3, PDB code: 7wjl was solved by N.N.Pang, S.Y.Che, N.Yang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.38 / 2.40
Space group	P 2 3
Cell size a, b, c (Å), α, β, γ (°)	124.542, 124.542, 124.542, 90, 90, 90
R / Rfree (%)	16.1 / 21

The binding sites of Zinc atom in the Crystal Structure of S. Cerevisiae HOS3 (pdb code 7wjl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of S. Cerevisiae HOS3, PDB code: 7wjl:

Zinc binding site 1 out of 1 in the Crystal Structure of S. Cerevisiae HOS3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of S. Cerevisiae HOS3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn601 b:65.6 occ:1.00 OD2 A:ASP370 2.5 47.7 1.0 OD1 A:ASP233 2.6 30.6 1.0 ND1 A:HIS235 2.6 38.4 1.0 OD2 A:ASP233 3.1 32.0 1.0 CG A:ASP233 3.2 33.7 1.0 OH A:TYR418 3.3 52.6 1.0 CE1 A:HIS235 3.4 29.1 1.0 NE2 A:HIS195 3.4 36.8 1.0 CE1 A:HIS195 3.4 34.8 1.0 CG A:ASP370 3.6 38.1 1.0 CG A:HIS235 3.6 32.5 1.0 CA A:GLY416 3.8 28.9 1.0 NE2 A:HIS196 3.9 28.8 1.0 CB A:HIS235 3.9 26.4 1.0 CE2 A:TYR418 4.1 43.0 1.0 OD1 A:ASP370 4.1 36.8 1.0 CZ A:TYR418 4.1 43.9 1.0 N A:GLY416 4.5 28.8 1.0 NE2 A:HIS235 4.6 36.5 1.0 CB A:ASP233 4.6 27.1 1.0 CD2 A:HIS196 4.6 24.3 1.0 N A:HIS235 4.7 28.2 1.0 CD2 A:HIS235 4.7 35.1 1.0 ND1 A:HIS195 4.7 34.2 1.0 CB A:ASP370 4.8 28.6 1.0 CD2 A:HIS195 4.8 31.9 1.0 CE1 A:HIS196 4.8 27.3 1.0 C A:GLY416 4.8 36.2 1.0 N A:GLY417 4.9 44.2 1.0 CA A:HIS235 5.0 29.1 1.0

N.N.Pang, S.Y.Che, J.X.Sun, N.Yang. Structural Study of Fungal Specific Histone Deacetylase HOS3 and Insight Into Developing Selective Inhibitors with Antifungal Activity To Be Published.