Zinc in PDB 7wbp: Crystal Structure of the Receptor Binding Domain of Sars-Cov-2 Omicron Variant Spike Glycoprotein in Complex with Its Receptor Human ACE2

Enzymatic activity of Crystal Structure of the Receptor Binding Domain of Sars-Cov-2 Omicron Variant Spike Glycoprotein in Complex with Its Receptor Human ACE2

All present enzymatic activity of Crystal Structure of the Receptor Binding Domain of Sars-Cov-2 Omicron Variant Spike Glycoprotein in Complex with Its Receptor Human ACE2:
3.4.17.23;

Protein crystallography data

The structure of Crystal Structure of the Receptor Binding Domain of Sars-Cov-2 Omicron Variant Spike Glycoprotein in Complex with Its Receptor Human ACE2, PDB code: 7wbp was solved by J.Qi, P.Han, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.62 / 3.00
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 104.238, 104.238, 227.178, 90, 90, 90
R / Rfree (%) 18.1 / 20.4

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of the Receptor Binding Domain of Sars-Cov-2 Omicron Variant Spike Glycoprotein in Complex with Its Receptor Human ACE2 (pdb code 7wbp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Receptor Binding Domain of Sars-Cov-2 Omicron Variant Spike Glycoprotein in Complex with Its Receptor Human ACE2, PDB code: 7wbp:

Zinc binding site 1 out of 1 in 7wbp

Go back to Zinc Binding Sites List in 7wbp
Zinc binding site 1 out of 1 in the Crystal Structure of the Receptor Binding Domain of Sars-Cov-2 Omicron Variant Spike Glycoprotein in Complex with Its Receptor Human ACE2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Receptor Binding Domain of Sars-Cov-2 Omicron Variant Spike Glycoprotein in Complex with Its Receptor Human ACE2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn704

b:71.5
occ:1.00
 OE2 A:GLU402 2.1 55.0 1.0
NE2 A:HIS374 2.1 57.3 1.0
NE2 A:HIS378 2.1 45.4 1.0
CD2 A:HIS374 3.0 46.5 1.0
CD2 A:HIS378 3.0 46.8 1.0
CD A:GLU402 3.0 48.0 1.0
CE1 A:HIS378 3.1 41.6 1.0
CE1 A:HIS374 3.2 46.8 1.0
OE1 A:GLU402 3.3 43.1 1.0
OE2 A:GLU375 3.7 49.7 1.0
CG A:HIS374 4.2 41.6 1.0
CG A:HIS378 4.2 43.0 1.0
ND1 A:HIS378 4.2 37.3 1.0
ND1 A:HIS374 4.2 48.1 1.0
CG A:GLU402 4.3 44.8 1.0
CD A:GLU375 4.4 48.2 1.0
OE1 A:GLU375 4.4 44.7 1.0

Reference:

P.Han, L.Li, S.Liu, Q.Wang, D.Zhang, Z.Xu, P.Han, X.Li, Q.Peng, C.Su, B.Huang, D.Li, R.Zhang, M.Tian, L.Fu, Y.Gao, X.Zhao, K.Liu, J.Qi, G.F.Gao, P.Wang. Receptor Binding and Complex Structures of Human ACE2 to Spike Rbd From Omicron and Delta Sars-Cov-2. Cell V. 185 630 2022.
ISSN: ISSN 1097-4172
PubMed: 35093192
DOI: 10.1016/J.CELL.2022.01.001
Page generated: Wed Oct 30 14:20:51 2024

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