Zinc in PDB 7wbl: Cryo-Em Structure of Human ACE2 Complexed with Sars-Cov-2 Omicron Rbd

All present enzymatic activity of Cryo-Em Structure of Human ACE2 Complexed with Sars-Cov-2 Omicron Rbd:
3.4.17.23;

The binding sites of Zinc atom in the Cryo-Em Structure of Human ACE2 Complexed with Sars-Cov-2 Omicron Rbd (pdb code 7wbl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Human ACE2 Complexed with Sars-Cov-2 Omicron Rbd, PDB code: 7wbl:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Human ACE2 Complexed with Sars-Cov-2 Omicron Rbd


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Human ACE2 Complexed with Sars-Cov-2 Omicron Rbd within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn805 b:46.1 occ:1.00 OE2 A:GLU402 2.2 21.6 1.0 NE2 A:HIS378 2.3 21.6 1.0 NE2 A:HIS374 2.3 21.6 1.0 CD A:GLU402 2.7 21.6 1.0 OE1 A:GLU402 2.9 21.6 1.0 CD2 A:HIS378 3.2 21.6 1.0 CD2 A:HIS374 3.2 21.6 1.0 CE1 A:HIS374 3.2 21.6 1.0 CE1 A:HIS378 3.3 21.6 1.0 CG A:GLU402 4.0 21.6 1.0 ND1 A:HIS374 4.3 21.6 1.0 CG A:HIS374 4.3 21.6 1.0 CG A:HIS378 4.4 21.6 1.0 ND1 A:HIS378 4.4 21.6 1.0 OE2 A:GLU375 4.6 21.6 1.0 CB A:GLU402 4.7 21.6 1.0 CA A:GLU402 4.9 21.6 1.0

P.Han, L.Li, S.Liu, Q.Wang, D.Zhang, Z.Xu, P.Han, X.Li, Q.Peng, C.Su, B.Huang, D.Li, R.Zhang, M.Tian, L.Fu, Y.Gao, X.Zhao, K.Liu, J.Qi, G.F.Gao, P.Wang. Receptor Binding and Complex Structures of Human ACE2 to Spike Rbd From Omicron and Delta Sars-Cov-2. Cell V. 185 630 2022.
ISSN: ISSN 1097-4172
PubMed: 35093192
DOI: 10.1016/J.CELL.2022.01.001