Zinc in PDB 7w7h: S Suis Faka-FAKB2 Complex Structure

The structure of S Suis Faka-FAKB2 Complex Structure, PDB code: 7w7h was solved by Y.Shi, N.Zang, N.Lou, Y.Xu, J.Sun, M.Huang, H.Zhang, H.Lu, C.Zhou, Y.Feng, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.26 / 2.60
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	107.749, 107.749, 398.999, 90, 90, 90
R / Rfree (%)	18.2 / 22.1

The binding sites of Zinc atom in the S Suis Faka-FAKB2 Complex Structure (pdb code 7w7h). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the S Suis Faka-FAKB2 Complex Structure, PDB code: 7w7h:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the S Suis Faka-FAKB2 Complex Structure


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of S Suis Faka-FAKB2 Complex Structure within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn601 b:78.7 occ:1.00 NE2 A:HIS289 1.9 83.1 1.0 NE2 A:HIS226 1.9 84.5 1.0 NE2 A:HIS291 2.0 83.2 1.0 SG A:CYS244 2.4 75.5 1.0 CE1 A:HIS289 2.8 73.7 1.0 CD2 A:HIS291 2.8 75.5 1.0 CE1 A:HIS226 2.9 73.7 1.0 CD2 A:HIS226 3.0 75.9 1.0 CD2 A:HIS289 3.0 77.3 1.0 CE1 A:HIS291 3.0 73.5 1.0 CB A:CYS244 3.4 69.3 1.0 ND1 A:HIS289 3.9 76.6 1.0 ND1 A:HIS226 4.0 76.8 1.0 CG A:HIS291 4.0 78.0 1.0 CG A:HIS289 4.1 73.5 1.0 ND1 A:HIS291 4.1 74.1 1.0 CG A:HIS226 4.1 77.6 1.0 CA A:CYS244 4.2 68.9 1.0 CG2 A:ILE222 4.5 59.9 1.0 SD A:MET316 4.9 85.0 1.0 C A:CYS244 4.9 77.8 1.0

Zinc binding site 2 out of 2 in the S Suis Faka-FAKB2 Complex Structure


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of S Suis Faka-FAKB2 Complex Structure within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn601 b:72.7 occ:1.00 NE2 B:HIS291 1.9 76.8 1.0 NE2 B:HIS226 2.0 85.9 1.0 NE2 B:HIS289 2.0 79.5 1.0 SG B:CYS244 2.3 76.2 1.0 CD2 B:HIS291 2.9 72.7 1.0 CE1 B:HIS291 2.9 69.9 1.0 CE1 B:HIS226 2.9 78.5 1.0 CE1 B:HIS289 2.9 73.0 1.0 CD2 B:HIS226 3.0 77.4 1.0 CD2 B:HIS289 3.0 73.3 1.0 CB B:CYS244 3.4 69.4 1.0 ND1 B:HIS291 4.0 71.2 1.0 CG B:HIS291 4.0 72.2 1.0 ND1 B:HIS226 4.0 81.7 1.0 ND1 B:HIS289 4.1 72.5 1.0 CG B:HIS226 4.1 79.9 1.0 CA B:CYS244 4.1 70.7 1.0 CG B:HIS289 4.1 72.9 1.0 CG2 B:ILE222 4.5 61.7 1.0 C B:CYS244 4.9 73.0 1.0 SD B:MET316 5.0 78.0 1.0

Y.Shi, N.Zang, N.Lou, Y.Xu, J.Sun, M.Huang, H.Zhang, H.Lu, C.Zhou, Y.Feng. Structure and Mechanism For Streptococcal Fatty Acid Kinase (Fak) System Dedicated to Host Fatty Acid Scavenging. Sci Adv V. 8 Q3944 2022.
ISSN: ESSN 2375-2548
PubMed: 36054360
DOI: 10.1126/SCIADV.ABQ3944