Zinc in PDB 7uy8: Tetrahymena Polymerase Alpha-Primase

All present enzymatic activity of Tetrahymena Polymerase Alpha-Primase:
2.7.7.7;

The binding sites of Zinc atom in the Tetrahymena Polymerase Alpha-Primase (pdb code 7uy8). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Tetrahymena Polymerase Alpha-Primase, PDB code: 7uy8:

Zinc binding site 1 out of 1 in the Tetrahymena Polymerase Alpha-Primase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Tetrahymena Polymerase Alpha-Primase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1401 b:180.8 occ:1.00 SG A:CYS1251 2.3 107.9 1.0 SG A:CYS1273 2.3 116.4 1.0 SG A:CYS1248 2.3 104.8 1.0 SG A:CYS1275 2.3 130.4 1.0 CB A:CYS1248 3.3 104.8 1.0 CB A:CYS1273 3.4 116.4 1.0 CB A:CYS1275 3.5 130.4 1.0 O A:LYS1249 3.5 107.2 1.0 N A:CYS1275 4.0 130.4 1.0 CB A:CYS1251 4.1 107.9 1.0 CA A:CYS1275 4.4 130.4 1.0 N A:LYS1249 4.4 107.2 1.0 N A:LYS1274 4.6 114.2 1.0 CA A:CYS1248 4.6 104.8 1.0 C A:LYS1249 4.6 107.2 1.0 C A:CYS1248 4.7 104.8 1.0 CA A:CYS1273 4.8 116.4 1.0 O A:CYS1251 4.8 107.9 1.0 CA A:CYS1251 5.0 107.9 1.0

Y.He, H.Song, H.Chan, B.Liu, Y.Wang, L.Susac, Z.H.Zhou, J.Feigon. Structure of Tetrahymena Telomerase-Bound Cst with Polymerase Alpha-Primase. Nature V. 608 813 2022.
ISSN: ESSN 1476-4687
PubMed: 35831498
DOI: 10.1038/S41586-022-04931-7