Zinc in PDB 7uy6: Tetrahymena Telomerase at 2.9 Angstrom Resolution

All present enzymatic activity of Tetrahymena Telomerase at 2.9 Angstrom Resolution:
2.7.7.49;

The binding sites of Zinc atom in the Tetrahymena Telomerase at 2.9 Angstrom Resolution (pdb code 7uy6). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Tetrahymena Telomerase at 2.9 Angstrom Resolution, PDB code: 7uy6:

Zinc binding site 1 out of 1 in the Tetrahymena Telomerase at 2.9 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Tetrahymena Telomerase at 2.9 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn900 b:189.9 occ:1.00 SG D:CYS572 2.3 101.6 1.0 SG D:CYS557 2.3 107.4 1.0 SG D:CYS555 2.3 102.7 1.0 SG D:CYS575 2.3 108.2 1.0 CB D:CYS575 2.8 108.2 1.0 CB D:CYS572 2.9 101.6 1.0 CB D:CYS555 3.3 102.7 1.0 N D:CYS575 3.5 108.2 1.0 CA D:CYS575 3.7 108.2 1.0 CB D:CYS557 3.8 107.4 1.0 C D:SER574 4.2 104.9 1.0 N D:CYS557 4.3 107.4 1.0 CA D:CYS572 4.4 101.6 1.0 CA D:CYS557 4.5 107.4 1.0 CG2 D:ILE579 4.5 95.5 1.0 N D:SER574 4.6 104.9 1.0 CB D:SER574 4.6 104.9 1.0 CA D:SER574 4.7 104.9 1.0 CD1 D:ILE579 4.7 95.5 1.0 CA D:CYS555 4.7 102.7 1.0 C D:CYS575 4.7 108.2 1.0 CA D:GLY559 4.8 98.9 1.0 C D:CYS572 4.8 101.6 1.0 C D:CYS557 4.8 107.4 1.0 N D:GLN576 4.9 100.0 1.0 N D:GLY559 4.9 98.9 1.0 N D:THR556 4.9 103.3 1.0

Y.He, H.Song, H.Chan, B.Liu, Y.Wang, L.Susac, Z.H.Zhou, J.Feigon. Structure of Tetrahymena Telomerase-Bound Cst with Polymerase Alpha-Primase. Nature V. 608 813 2022.
ISSN: ESSN 1476-4687
PubMed: 35831498
DOI: 10.1038/S41586-022-04931-7