Zinc in PDB 7upn: Maedi Visna Virus Vif in Complex with Cypa and E3 Ubiquitin Ligase

All present enzymatic activity of Maedi Visna Virus Vif in Complex with Cypa and E3 Ubiquitin Ligase:
5.2.1.8;

The binding sites of Zinc atom in the Maedi Visna Virus Vif in Complex with Cypa and E3 Ubiquitin Ligase (pdb code 7upn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Maedi Visna Virus Vif in Complex with Cypa and E3 Ubiquitin Ligase, PDB code: 7upn:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Maedi Visna Virus Vif in Complex with Cypa and E3 Ubiquitin Ligase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Maedi Visna Virus Vif in Complex with Cypa and E3 Ubiquitin Ligase within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn301 b:127.5 occ:1.00 SG C:CYS137 2.3 97.9 1.0 SG C:CYS135 2.3 94.8 1.0 SG C:CYS157 2.3 93.1 1.0 SG C:CYS160 2.3 84.5 1.0 CB C:CYS157 3.3 93.1 1.0 CB C:CYS135 3.5 94.8 1.0 CB C:CYS137 3.7 97.9 1.0 CB C:CYS160 3.9 84.5 1.0 N C:CYS157 4.0 93.1 1.0 CA C:CYS157 4.3 93.1 1.0 CA C:CYS135 4.7 94.8 1.0 O C:SER136 4.7 96.0 1.0 C C:CYS135 4.8 94.8 1.0 N C:SER136 4.9 96.0 1.0 C C:SER136 4.9 96.0 1.0 CA C:CYS137 4.9 97.9 1.0 N C:CYS137 4.9 97.9 1.0

Zinc binding site 2 out of 2 in the Maedi Visna Virus Vif in Complex with Cypa and E3 Ubiquitin Ligase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Maedi Visna Virus Vif in Complex with Cypa and E3 Ubiquitin Ligase within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn301 b:128.4 occ:1.00 SG F:CYS137 2.3 100.4 1.0 SG F:CYS135 2.3 94.3 1.0 SG F:CYS157 2.3 93.4 1.0 SG F:CYS160 2.3 84.6 1.0 CB F:CYS157 3.3 93.4 1.0 CB F:CYS135 3.5 94.3 1.0 CB F:CYS137 3.7 100.4 1.0 CB F:CYS160 3.9 84.6 1.0 N F:CYS157 4.0 93.4 1.0 CA F:CYS157 4.3 93.4 1.0 CA F:CYS135 4.7 94.3 1.0 O F:SER136 4.8 96.5 1.0 C F:CYS135 4.8 94.3 1.0 N F:SER136 4.9 96.5 1.0 C F:SER136 4.9 96.5 1.0 CA F:CYS137 4.9 100.4 1.0 N F:CYS137 4.9 100.4 1.0

Y.Hu, R.B.Gudnadottir, K.M.Knecht, F.Arizaga, S.R.Jonsson, Y.Xiong. Structural Basis For Recruitment of Host Cypa and E3 Ubiquitin Ligase By Maedi-Visna Virus Vif. Sci Adv V. 9 D3422 2023.
ISSN: ESSN 2375-2548
PubMed: 36638173
DOI: 10.1126/SCIADV.ADD3422