Zinc in PDB 7uhq: Time-Resolved Structure of Metallo Beta-Lactamase L1 in A Complex with Cleaved Moxalactam (4000 Ms Snapshot)

All present enzymatic activity of Time-Resolved Structure of Metallo Beta-Lactamase L1 in A Complex with Cleaved Moxalactam (4000 Ms Snapshot):
3.5.2.6;

The structure of Time-Resolved Structure of Metallo Beta-Lactamase L1 in A Complex with Cleaved Moxalactam (4000 Ms Snapshot), PDB code: 7uhq was solved by M.Wilamowski, Y.Kim, D.A.Sherrell, A.Lavens, R.Henning, N.Maltseva, M.Endres, G.Babnigg, V.Srajer, A.Joachimiak, Center For Structuralgenomics Of Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.65 / 2.20
Space group	P 64 2 2
Cell size a, b, c (Å), α, β, γ (°)	105.853, 105.853, 99.1, 90, 90, 120
R / Rfree (%)	23.3 / 26.4

The binding sites of Zinc atom in the Time-Resolved Structure of Metallo Beta-Lactamase L1 in A Complex with Cleaved Moxalactam (4000 Ms Snapshot) (pdb code 7uhq). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Time-Resolved Structure of Metallo Beta-Lactamase L1 in A Complex with Cleaved Moxalactam (4000 Ms Snapshot), PDB code: 7uhq:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Time-Resolved Structure of Metallo Beta-Lactamase L1 in A Complex with Cleaved Moxalactam (4000 Ms Snapshot)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Time-Resolved Structure of Metallo Beta-Lactamase L1 in A Complex with Cleaved Moxalactam (4000 Ms Snapshot) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:28.0 occ:0.61 O10 A:XQP303 2.1 28.6 0.8 ND1 A:HIS107 2.3 15.4 1.0 NE2 A:HIS105 2.3 13.0 1.0 NE2 A:HIS181 2.5 20.2 1.0 CD2 A:HIS181 3.1 19.9 1.0 CG A:HIS107 3.2 15.6 1.0 CD2 A:HIS105 3.3 12.8 1.0 CE1 A:HIS105 3.3 12.8 1.0 CB A:HIS107 3.3 15.9 1.0 CE1 A:HIS107 3.3 15.6 1.0 C1 A:XQP303 3.3 28.7 0.8 ZN A:ZN302 3.4 14.2 0.7 CE1 A:HIS181 3.6 20.3 1.0 O8 A:XQP303 3.6 28.1 0.8 OD1 A:ASP109 3.7 20.4 1.0 O3 A:XQP303 3.8 28.1 0.8 N1 A:XQP303 3.8 28.2 0.8 CD2 A:HIS110 3.8 16.4 1.0 NE2 A:HIS110 3.9 16.7 1.0 C7 A:XQP303 4.0 28.4 0.8 C6 A:XQP303 4.1 28.6 0.8 O1 A:XQP303 4.3 28.9 0.8 C20 A:XQP303 4.3 28.2 0.8 CD2 A:HIS107 4.3 15.7 1.0 ND1 A:HIS105 4.4 12.6 1.0 CG A:HIS181 4.4 19.7 1.0 CG A:HIS105 4.4 12.8 1.0 NE2 A:HIS107 4.4 15.6 1.0 C2 A:XQP303 4.5 28.4 0.8 OD2 A:ASP109 4.5 20.3 1.0 ND1 A:HIS181 4.6 20.1 1.0 CG A:ASP109 4.6 20.1 1.0 C5 A:XQP303 4.6 28.8 0.8 CA A:HIS107 4.8 16.2 1.0

Zinc binding site 2 out of 2 in the Time-Resolved Structure of Metallo Beta-Lactamase L1 in A Complex with Cleaved Moxalactam (4000 Ms Snapshot)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Time-Resolved Structure of Metallo Beta-Lactamase L1 in A Complex with Cleaved Moxalactam (4000 Ms Snapshot) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:14.2 occ:0.66 OD2 A:ASP109 2.1 20.3 1.0 NE2 A:HIS110 2.2 16.7 1.0 N1 A:XQP303 2.2 28.2 0.8 O8 A:XQP303 2.3 28.1 0.8 NE2 A:HIS246 2.3 23.4 1.0 C2 A:XQP303 3.0 28.4 0.8 CG A:ASP109 3.0 20.1 1.0 C20 A:XQP303 3.1 28.2 0.8 CE1 A:HIS110 3.1 16.8 1.0 CD2 A:HIS110 3.2 16.4 1.0 C5 A:XQP303 3.2 28.8 0.8 CE1 A:HIS246 3.3 23.7 1.0 OD1 A:ASP109 3.3 20.4 1.0 CD2 A:HIS246 3.3 23.8 1.0 ZN A:ZN301 3.4 28.0 0.6 O10 A:XQP303 3.6 28.6 0.8 O3 A:XQP303 3.8 28.1 0.8 C6 A:XQP303 4.0 28.6 0.8 C1 A:XQP303 4.2 28.7 0.8 ND1 A:HIS110 4.2 16.4 1.0 O9 A:XQP303 4.3 28.1 0.8 C3 A:XQP303 4.3 28.8 0.8 NE2 A:HIS105 4.3 13.0 1.0 CG A:HIS110 4.3 16.3 1.0 CE1 A:HIS105 4.4 12.8 1.0 ND1 A:HIS246 4.4 23.8 1.0 O2 A:XQP303 4.4 29.3 0.8 CB A:ASP109 4.4 19.5 1.0 CG A:HIS246 4.5 23.8 1.0 NE2 A:HIS181 4.8 20.2 1.0 CH2 A:TRP38 4.8 32.7 1.0 C4 A:XQP303 4.9 29.2 0.8 OG A:SER206 4.9 24.7 1.0 C7 A:XQP303 5.0 28.4 0.8

M.Wilamowski, Y.Kim, D.A.Sherrell, A.Lavens, R.Henning, N.Maltseva, M.Endres, G.Babnigg, V.Srajer, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid). Time-Resolved Structure of Metallo Beta-Lactamase L1 in A Complex with Cleaved Moxalactam (4000 Ms Snapshot) To Be Published.