Zinc in PDB 7u5v: Crystal Structure of the Mixed Lineage Leukaemia (MLL1) Set Domain with the Cofactor Product S-Adenosylhomocysteine and Borealin Peptide

The structure of Crystal Structure of the Mixed Lineage Leukaemia (MLL1) Set Domain with the Cofactor Product S-Adenosylhomocysteine and Borealin Peptide, PDB code: 7u5v was solved by S.An, U.S.Cho, H.Oh, L.Sha, J.Xu, S.Kim, W.Yang, W.An, Y.Dou, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.08 / 2.59
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	54.48, 54.48, 105.63, 90, 90, 120
R / Rfree (%)	24.8 / 30.4

The binding sites of Zinc atom in the Crystal Structure of the Mixed Lineage Leukaemia (MLL1) Set Domain with the Cofactor Product S-Adenosylhomocysteine and Borealin Peptide (pdb code 7u5v). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Mixed Lineage Leukaemia (MLL1) Set Domain with the Cofactor Product S-Adenosylhomocysteine and Borealin Peptide, PDB code: 7u5v:

Zinc binding site 1 out of 1 in the Crystal Structure of the Mixed Lineage Leukaemia (MLL1) Set Domain with the Cofactor Product S-Adenosylhomocysteine and Borealin Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Mixed Lineage Leukaemia (MLL1) Set Domain with the Cofactor Product S-Adenosylhomocysteine and Borealin Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn4001 b:142.9 occ:1.00 SG A:CYS3909 2.3 118.4 1.0 CB A:CYS3909 2.8 106.8 1.0 N A:CYS3909 3.0 94.4 1.0 CA A:CYS3909 3.5 99.7 1.0 C A:SER3908 4.1 78.3 1.0 CA A:SER3908 4.4 72.0 1.0 C A:CYS3909 4.4 96.5 1.0 NE2 A:HIS3907 4.5 82.8 1.0 N A:GLU3910 4.7 84.8 1.0 CD2 A:HIS3907 4.9 76.2 1.0 OG A:SER3908 4.9 70.7 1.0

S.An, U.S.Cho, H.Oh, L.Sha, J.Xu, S.Kim, W.Yang, W.An, Y.Dou. Crystal Structure of the Mixed Lineage Leukaemia (MLL1) Set Domain with the Cofactor Product S-Adenosylhomocysteine and Borealin Peptide. To Be Published.