Zinc in PDB 7sus: Crystal Structure of Apelin Receptor in Complex with Small Molecule

The structure of Crystal Structure of Apelin Receptor in Complex with Small Molecule, PDB code: 7sus was solved by F.Xu, Y.Yue, L.E.Liu, G.W.Han, M.Hanson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.70
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	163.01, 44.56, 79.68, 90, 115.62, 90
R / Rfree (%)	25.2 / 27.4

The binding sites of Zinc atom in the Crystal Structure of Apelin Receptor in Complex with Small Molecule (pdb code 7sus). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Apelin Receptor in Complex with Small Molecule, PDB code: 7sus:

Zinc binding site 1 out of 1 in the Crystal Structure of Apelin Receptor in Complex with Small Molecule


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Apelin Receptor in Complex with Small Molecule within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1101 b:99.9 occ:1.00 SG A:CYS1042 2.2 94.4 1.0 SG A:CYS1039 2.3 97.4 1.0 SG A:CYS1006 2.4 95.3 1.0 SG A:CYS1009 2.5 97.9 1.0 CB A:CYS1039 3.2 93.3 1.0 CB A:CYS1006 3.3 91.3 1.0 CB A:CYS1009 3.6 94.4 1.0 CB A:CYS1042 3.6 91.0 1.0 CG2 A:VAL1044 3.9 93.1 1.0 N A:CYS1009 3.9 94.0 1.0 N A:CYS1042 4.0 91.2 1.0 CA A:CYS1009 4.3 94.2 1.0 CA A:CYS1042 4.4 90.8 1.0 CB A:TYR1011 4.4 96.5 1.0 N A:GLY1010 4.7 95.1 1.0 CA A:CYS1039 4.7 93.0 1.0 CA A:CYS1006 4.7 91.1 1.0 N A:TYR1011 4.8 95.6 1.0 CB A:VAL1008 4.8 96.7 1.0 CB A:LEU1041 4.8 92.2 1.0 CZ A:PHE1049 4.8 95.1 1.0 C A:LEU1041 4.9 95.4 1.0 C A:CYS1042 5.0 94.1 1.0 N A:GLY1043 5.0 90.2 1.0

Y.Yue, L.Liu, L.J.Wu, Y.Wu, L.Wang, F.Li, J.Liu, G.W.Han, B.Chen, X.Lin, R.L.Brouillette, E.Breault, J.M.Longpre, S.Shi, H.Lei, P.Sarret, R.C.Stevens, M.A.Hanson, F.Xu. Structural Insight Into Apelin Receptor-G Protein Stoichiometry. Nat.Struct.Mol.Biol. V. 29 688 2022.
ISSN: ESSN 1545-9985
PubMed: 35817871
DOI: 10.1038/S41594-022-00797-5