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Zinc in PDB 7skq: Btscov-RF1.2004 Papain-Like Protease Bound to the Non-Covalent Inhibitor Grl-0617Enzymatic activity of Btscov-RF1.2004 Papain-Like Protease Bound to the Non-Covalent Inhibitor Grl-0617
All present enzymatic activity of Btscov-RF1.2004 Papain-Like Protease Bound to the Non-Covalent Inhibitor Grl-0617:
3.4.19.12; 3.4.22.69; Protein crystallography data
The structure of Btscov-RF1.2004 Papain-Like Protease Bound to the Non-Covalent Inhibitor Grl-0617, PDB code: 7skq
was solved by
B.Freitas,
I.Durie,
J.Shepard,
B.O'boyle,
S.Enos,
S.D.Pegan,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Btscov-RF1.2004 Papain-Like Protease Bound to the Non-Covalent Inhibitor Grl-0617
(pdb code 7skq). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Btscov-RF1.2004 Papain-Like Protease Bound to the Non-Covalent Inhibitor Grl-0617, PDB code: 7skq: Jump to Zinc binding site number: 1; 2; 3; 4; Zinc binding site 1 out of 4 in 7skqGo back to Zinc Binding Sites List in 7skq
Zinc binding site 1 out
of 4 in the Btscov-RF1.2004 Papain-Like Protease Bound to the Non-Covalent Inhibitor Grl-0617
Mono view Stereo pair view
Zinc binding site 2 out of 4 in 7skqGo back to Zinc Binding Sites List in 7skq
Zinc binding site 2 out
of 4 in the Btscov-RF1.2004 Papain-Like Protease Bound to the Non-Covalent Inhibitor Grl-0617
Mono view Stereo pair view
Zinc binding site 3 out of 4 in 7skqGo back to Zinc Binding Sites List in 7skq
Zinc binding site 3 out
of 4 in the Btscov-RF1.2004 Papain-Like Protease Bound to the Non-Covalent Inhibitor Grl-0617
Mono view Stereo pair view
Zinc binding site 4 out of 4 in 7skqGo back to Zinc Binding Sites List in 7skq
Zinc binding site 4 out
of 4 in the Btscov-RF1.2004 Papain-Like Protease Bound to the Non-Covalent Inhibitor Grl-0617
Mono view Stereo pair view
Reference:
B.T.Freitas,
D.A.Ahiadorme,
R.S.Bagul,
I.A.Durie,
S.Ghosh,
J.Hill,
N.E.Kramer,
J.Murray,
B.M.O'boyle,
E.Onobun,
M.G.Pirrone,
J.D.Shepard,
S.Enos,
Y.P.Subedi,
K.Upadhyaya,
R.A.Tripp,
B.S.Cummings,
D.Crich,
S.D.Pegan.
Exploring Noncovalent Protease Inhibitors For the Treatment of Severe Acute Respiratory Syndrome and Severe Acute Respiratory Syndrome-Like Coronaviruses. Acs Infect Dis. V. 8 596 2022.
Page generated: Sat Apr 8 03:15:11 2023
ISSN: ESSN 2373-8227 PubMed: 35199517 DOI: 10.1021/ACSINFECDIS.1C00631 |
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