Zinc in PDB 7sgv: Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with PLP_SNYDER630 Inhibitor

Enzymatic activity of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with PLP_SNYDER630 Inhibitor

All present enzymatic activity of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with PLP_SNYDER630 Inhibitor:
3.4.19.12;

Protein crystallography data

The structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with PLP_SNYDER630 Inhibitor, PDB code: 7sgv was solved by J.Osipiuk, C.Tesar, M.Endres, V.Lisnyak, S.Maki, C.Taylor, Y.Zhang, Z.Zhou, S.A.Azizi, K.Jones, R.Kathayat, S.A.Snyder, B.C.Dickinson, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 44.71 / 2.00
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 82.982, 82.982, 134.021, 90, 90, 120
R / Rfree (%) 18.1 / 20.7

Other elements in 7sgv:

The structure of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with PLP_SNYDER630 Inhibitor also contains other interesting chemical elements:

Chlorine (Cl) 4 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with PLP_SNYDER630 Inhibitor (pdb code 7sgv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with PLP_SNYDER630 Inhibitor, PDB code: 7sgv:

Zinc binding site 1 out of 1 in 7sgv

Go back to Zinc Binding Sites List in 7sgv
Zinc binding site 1 out of 1 in the Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with PLP_SNYDER630 Inhibitor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with PLP_SNYDER630 Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn502

b:158.4
occ:1.00
SG A:CYS189 2.8 100.8 1.0
N A:GLY227 3.5 105.0 1.0
CB A:CYS189 4.2 113.3 1.0
CA A:GLY227 4.9 105.3 1.0

Reference:

J.Osipiuk, C.Tesar, M.Endres, V.Lisnyak, S.Maki, C.Taylor, Y.Zhang, Z.Zhou, S.A.Azizi, K.Jones, R.Kathayat, S.A.Snyder, B.C.Dickinson, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid). Papain-Like Protease of Sars Cov-2, C111S Mutant, in Complex with PLP_SNYDER630 Inhibitor To Be Published.
Page generated: Fri Nov 5 17:01:05 2021

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